Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Martin F, Schneider"'
Autor:
Travis J. Morgenstern, Neha Nirwan, Erick O. Hernández-Ochoa, Hugo Bibollet, Papiya Choudhury, Yianni D. Laloudakis, Manu Ben Johny, Roger A. Bannister, Martin F. Schneider, Daniel L. Minor, Henry M. Colecraft
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Auxiliary subunit molecular diversity is an unexploited target for developing ion channel inhibitors. Here, the authors develop a general approach to inhibit ion channels based on the resident auxiliary subunit isoform to elucidate unique functions o
Externí odkaz:
https://doaj.org/article/6afcd6383eb345e8b49429eb383e8ae1
Autor:
Hugo Bibollet, Elton L. Nguyen, Daniel R. Miranda, Christopher W. Ward, Andrew A. Voss, Martin F. Schneider, Erick O. Hernández‐Ochoa
Publikováno v:
Physiological Reports, Vol 11, Iss 9, Pp n/a-n/a (2023)
Abstract In skeletal muscle, CaV1.1 serves as the voltage sensor for both excitation‐contraction coupling (ECC) and L‐type Ca2+ channel activation. We have recently adapted the technique of action potential (AP) voltage clamp (APVC) to monitor th
Externí odkaz:
https://doaj.org/article/936e352654cf477daee58c2bc9bd9210
Autor:
Qinchuan Wang, Erick O. Hernández-Ochoa, Meera C. Viswanathan, Ian D. Blum, Danh C. Do, Jonathan M. Granger, Kevin R. Murphy, An-Chi Wei, Susan Aja, Naili Liu, Corina M. Antonescu, Liliana D. Florea, C. Conover Talbot, David Mohr, Kathryn R. Wagner, Sergi Regot, Richard M. Lovering, Peisong Gao, Mario A. Bianchet, Mark N. Wu, Anthony Cammarato, Martin F. Schneider, Gabriel S. Bever, Mark E. Anderson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Natural selection may favor traits underlying aging-related diseases if they benefit the young. Wang et al. find that oxidative activation of CaMKII provides physiological benefits critical to the initial and continued success of vertebrates but at t
Externí odkaz:
https://doaj.org/article/6c13420d75db4c89a9f1e7180f0d0576
Autor:
Fernanda Carrizo Velasquez, Barbara Roman, Erick O. Hernández-Ochoa, Michelle K. Leppo, Sharon K. Truong, Charles Steenbergen, Martin F. Schneider, Robert G. Weiss, Samarjit Das
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H598-H609
Heart failure is associated with systemic insulin resistance and abnormalities in glucose metabolism but the underlying mechanisms are poorly understood. In the skeletal muscle, the major peripheral site of glucose utilization, we observe an increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff5bc608e956d6320b72f3d0668808d0
https://doi.org/10.1152/ajpheart.00250.2022
https://doi.org/10.1152/ajpheart.00250.2022
Autor:
Henrietta Cserne Szappanos, János Vincze, Dóra Bodnár, Beatrix Dienes, Martin F. Schneider, László Csernoch, Péter Szentesi
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
In amphibian skeletal muscle calcium (Ca2+) sparks occur both as voltage-dependent and voltage-independent ligand-activated release events. However, whether their properties and their origin show similarities are still in debate. Elevated K+, constan
Externí odkaz:
https://doaj.org/article/ff6e5e6b8cb841cd8fd95f9b3d1e5747
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-20 (2018)
Abstract The process by which muscle fiber electrical depolarization is linked to activation of muscle contraction is known as excitation-contraction coupling (ECC). Our understanding of ECC has increased enormously since the early scientific descrip
Externí odkaz:
https://doaj.org/article/d62cc58b2553405aab58ec7e329310cb
Publikováno v:
Calcium Signals ISBN: 9780750320092
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9e73cdc07f5ffdf18f9ec1a00f0204c
https://doi.org/10.1088/978-0-7503-2009-2ch8
https://doi.org/10.1088/978-0-7503-2009-2ch8
Autor:
Erick O. Hernández‐Ochoa, Zephan Melville, Camilo Vanegas, Kristen M. Varney, Paul T. Wilder, Werner Melzer, David J. Weber, Martin F. Schneider
Publikováno v:
Physiological Reports, Vol 6, Iss 15, Pp n/a-n/a (2018)
Abstract Calmodulin (CaM) and S100A1 fine‐tune skeletal muscle Ca2+ release via opposite modulation of the ryanodine receptor type 1 (RyR1). Binding to and modulation of RyR1 by CaM and S100A1 occurs predominantly at the region ranging from amino a
Externí odkaz:
https://doaj.org/article/8231af2f14e64b69a8b603a1214e2fbd
Publikováno v:
Visc Med
Background: Recurrence after resection of pancreatic cancer occurs in up to 80% of patients in the first 2 years after complete resection. While most patients are not eligible for surgical treatment due to disseminated disease, a certain group of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103331a30807b10965bf623092be155b
https://doi.org/10.1159/000519754
https://doi.org/10.1159/000519754
Publikováno v:
Journal of Diabetes Research, Vol 2017 (2017)
A common comorbidity of diabetes is skeletal muscle dysfunction, which leads to compromised physical function. Previous studies of diabetes in skeletal muscle have shown alterations in excitation-contraction coupling (ECC)—the sequential link betwe
Externí odkaz:
https://doaj.org/article/30ce00a4b8924e95a3951d483edf622d