Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Martin Engelstädter"'
Autor:
Martin Engelstädter, Heike Merget-Millitzer, RA Willemsen, Stefanie Steidl, Maria Bobkova, Klaus Cichutek, Christian J. Buchholz, Jörn Stitz
Publikováno v:
Gene Therapy. 8:1202-1206
In contrast to murine leukaemia virus (MLV)-derived vector systems, vector particles derived from the avian spleen necrosis virus (SNV) have been successfully targeted to subsets of human cells by envelope modification with antibody fragments (scFv).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131a9a2c6714d6f18c76fc6694acc559
https://doi.org/10.1038/sj.gt.3301500
https://doi.org/10.1038/sj.gt.3301500
Autor:
Klaus Cichutek, Roger J. Pomerantz, Zahida Parveen, Anna Krupetsky, Ralph Dornburg, Martin Engelstädter
Publikováno v:
Nature Biotechnology. 18:623-629
Gene therapy applications of retroviral vectors derived from C-type retroviruses have been limited to introducing genes into dividing target cells. Here, we report genetically engineered C-type retroviral vectors derived from spleen necrosis virus (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a165aa9fb7430955bea313412e607456
https://doi.org/10.1038/76458
https://doi.org/10.1038/76458
Autor:
Martin Engelstädter, Renate König, Frank Nocken, Maria Bobkova, Christian J. Buchholz, Jörn Stitz, Peter Müller, Isabel Schmitt, Stefanie Steidl, Heike Merget-Millitzer, Klaus Cichutek, Reinhard Kurth
Publikováno v:
Virology. 267:229-236
Retroviral vectors derived from amphotropic murine leukemia viruses (MLV) mediate gene transfer into almost all human cells and are thus not suitable for in vivo applications in gene therapy in which cell-specific gene delivery is required. We and ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bacfa34e45652ee4a7772d5dd91e956
https://doi.org/10.1006/viro.1999.0121
https://doi.org/10.1006/viro.1999.0121
Autor:
Te-Hua Tearina Chu, Klaus Cichutek, Reinhard Kurth, Martin Engelstädter, Maria Bobkova, Ralph Dornburg, Michael Baier, Christian J. Buchholz, Nicola Holtkamp, Jörn Stitz
Publikováno v:
Human Gene Therapy. 11:293-303
To generate T cell-specific retroviral vectors an scFv phage display library derived from immunized mice was selected for binding to the human T cell line Molt-4/8. The scFv cDNAs recovered from the selected phages were transiently expressed as an N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36eefc8d0adfca5be08202d98845df7
https://doi.org/10.1089/10430340050016030
https://doi.org/10.1089/10430340050016030
Autor:
Frank Nocken, Martin Engelstädter, Reinhard Kurth, Jörn Stitz, Klaus Cichutek, Heike Merget-Millitzer, Barbara S. Schnierle, Valerie Bosch, Bernd Groner
Publikováno v:
Proceedings of the National Academy of Sciences. 94:8640-8645
CD4-expressing T cells in lymphoid organs are infected by the primary strains of HIV and represent one of the main sources of virus replication. Gene therapy strategies are being developed that allow the transfer of exogenous genes into CD4 + T lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced81d44ad46b23447a7a13f47717ce7
https://doi.org/10.1073/pnas.94.16.8640
https://doi.org/10.1073/pnas.94.16.8640
Autor:
Jens Braner, Schlomo Staszewski, Peter Müller, Martin Engelstädter, Reinhard Kurth, Hans-Wilhelm Doerr, Veronica Miller, Klaus Cichutek, Albrecht Werner
Publikováno v:
Intervirology. 40:263-270
The serum levels of the beta-chemokine RANTES and, albeit less, MIP-1 beta were found to be increased in 37 HIV-1 infected compared to seronegative individuals. In contrast the serum levels of IL-16 were only sporadically elevated in seropositives as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc92ebfbb1c30f084a93d1ae6465de94
https://doi.org/10.1159/000150556
https://doi.org/10.1159/000150556
Autor:
Wolfgang Uckert, Jörn Stitz, Isabel Schmitt, Christian J. Buchholz, Klaus Cichutek, U. Bloemer, Martin Engelstädter
Publikováno v:
Virology. (1):16-20
Lentiviral vectors pseudotyped with the envelope glycoproteins (Env) of amphotropic murine leukemia virus (MLV) and the G protein of vesicular stomatitis virus (VSV-G) have been successfully used in recent preclinical gene therapy studies. We report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b175f2de370381e2c154bd6be34c113
Publikováno v:
Scopus-Elsevier
Activation of the murine leukaemia virus (MLV) envelope protein (Env) requires proteolytic cleavage of the R-peptide, a 16 amino acid C-terminal part of the cytoplasmic tail (C-tail) of Env. This paper demonstrates the presence of R-peptides in Env p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fd0212fe32925e6279f82aeace3d0f
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036711683&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036711683&partnerID=MN8TOARS
