Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Martin Enge"'
Autor:
Thale K. Olsen, Jörg Otte, Shenglin Mei, Bethel Tesfai Embaie, Polina Kameneva, Huaitao Cheng, Teng Gao, Vasilios Zachariadis, Ioanna Tsea, Åsa Björklund, Emil Kryukov, Ziyi Hou, Anna Johansson, Erik Sundström, Tommy Martinsson, Susanne Fransson, Jakob Stenman, Shahrzad Shirazi Fard, John Inge Johnsen, Per Kogner, Igor Adameyko, Martin Enge, Peter V. Kharchenko, Ninib Baryawno
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Neuroblastoma (NB) is a heterogeneous embryonal malignancy and the deadliest tumor of infancy. It is a complex disease that can result in diverse clinical outcomes. In some children, tumors regress spontaneously. Others respond we
Externí odkaz:
https://doaj.org/article/1d5da37f62bb4e9c8494a94bf33d81b4
Autor:
Caroline Lindblad, Susanne Neumann, Sólrún Kolbeinsdóttir, Vasilios Zachariadis, Eric P. Thelin, Martin Enge, Sebastian Thams, Lou Brundin, Mikael Svensson
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background Astrocytes respond to injury and disease through a process known as reactive astrogliosis, of which inflammatory signaling is one subset. This inflammatory response is heterogeneous with respect to the inductive stimuli and the af
Externí odkaz:
https://doaj.org/article/8b39860ab2eb440491d850d45468a07a
Autor:
Antonio Lentini, Huaitao Cheng, J. C. Noble, Natali Papanicolaou, Christos Coucoravas, Nathanael Andrews, Qiaolin Deng, Martin Enge, Björn Reinius
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The concerted dynamics of X-chromosome upregulation and X-chromosome inactivation, which collectively balance X-chromosome expression, are not well understood. Using allelic single-cell genomics, the authors characterize the dynamics of X-chromosome
Externí odkaz:
https://doaj.org/article/949ff02b1814415dbfce7936d7db6c4c
Autor:
Kai Zhou, Jinming Han, Harald Lund, Nageswara Rao Boggavarapu, Volker M Lauschke, Shinobu Goto, Huaitao Cheng, Yuyu Wang, Asuka Tachi, Cuicui Xie, Keying Zhu, Ying Sun, Ahmed M. Osman, Dong Liang, Wei Han, Kristina Gemzell-Danielsson, Christer Betsholtz, Xing-Mei Zhang, Changlian Zhu, Martin Enge, Bertrand Joseph, Robert A. Harris, Klas Blomgren
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Fluorescent reporter labeling and promoter-driven Cre-recombinant technologies have facilitated cellular investigations of physiological and pathological processes, including the widespread use of the Cx3cr1 CreER-Eyfp/wt mouse st
Externí odkaz:
https://doaj.org/article/add60eceb8c54a998f2ff155de0cb934
Autor:
Inderpreet Sur, Wenshuo Zhao, Jilin Zhang, Margareta Kling Pilström, Björn Rozell, Anna T. Webb, Huaitao Cheng, Ari Ristimäki, Pekka Katajisto, Martin Enge, Helena Rannikmae, Marc de la Roche, Jussi Taipale
Cancer has been characterized as a wound that does not heal. Malignant cells are morphologically distinct from normal proliferating cells, but have extensive similarities to tissues undergoing wound healing and/or regeneration. The mechanistic basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27b7fa1c9e98fcccc2b4ae3fa730d543
https://doi.org/10.1101/2022.11.04.515076
https://doi.org/10.1101/2022.11.04.515076
Autor:
Rosan Heijboer, Jason T. Serviss, Martin Enge, Agneta Andersson, Marco Gerling, Iva Šutevski, Ewa Dzwonkowska, Nathanael Andrews, Natalie Geyer, Ninib Baryawno
Publikováno v:
Nature Methods. 18:912-920
Cellular identity in complex multicellular organisms is determined in part by the physical organization of cells. However, large-scale investigation of the cellular interactome remains technically challenging. Here we develop cell interaction by mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::233ad5e8e8c4575fced1cf9957789d8d
https://doi.org/10.1038/s41592-021-01196-2
https://doi.org/10.1038/s41592-021-01196-2
Autor:
Eliza Duvall, Cecil M. Benitez, Krissie Tellez, Martin Enge, Philip T. Pauerstein, Lingyu Li, Songjoon Baek, Stephen R. Quake, Jason P. Smith, Nathan C. Sheffield, Seung K. Kim, H. Efsun Arda
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 26
Delineating gene regulatory networks that orchestrate cell-type specification is an ongoing challenge for developmental biology studies. Single-cell analyses offer opportunities to address these challenges and accelerate discovery of rare cell lineag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790573a1091c25bc1d5268d9b15f4cec
https://doi.org/10.1073/pnas.2201267119
https://doi.org/10.1073/pnas.2201267119
Autor:
Tamasha Malepathirana, Damith Senanayake, Vini Gautam, Martin Engel, Rachelle Balez, Michael D. Lovelace, Gayathri Sundaram, Benjamin Heng, Sharron Chow, Christopher Marquis, Gilles J. Guillemin, Bruce Brew, Chennupati Jagadish, Lezanne Ooi, Saman Halgamuge
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Longitudinal studies that continuously generate data enable the capture of temporal variations in experimentally observed parameters, facilitating the interpretation of results in a time-aware manner. We propose IL-VIS (incrementally learned
Externí odkaz:
https://doaj.org/article/aa2a103c819e4d3bb068dba74abcfa87
Autor:
Simon Maksour, Rocio K. Finol-Urdaneta, Amy J. Hulme, Mauricio e Castro Cabral-da-Silva, Helena Targa Dias Anastacio, Rachelle Balez, Tracey Berg, Calista Turner, Sonia Sanz Muñoz, Martin Engel, Predrag Kalajdzic, Leszek Lisowski, Kuldip Sidhu, Perminder S. Sachdev, Mirella Dottori, Lezanne Ooi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Alzheimer’s disease (AD) is a devastating neurodegenerative condition that affects memory and cognition, characterized by neuronal loss and currently lacking a cure. Mutations in PSEN1 (Presenilin 1) are among the most common causes of early-onset
Externí odkaz:
https://doaj.org/article/05ddb18cdd304f6b868ce5b095ddf6d6
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103234- (2024)
Summary: To improve human hepatotoxicity prediction, in vitro liver cell models replicating hepatocyte function, drug metabolism, and toxicity are required. Here, we present a protocol for creating 3D primary human hepatocyte (PHH) cell models using
Externí odkaz:
https://doaj.org/article/f4b054c43be74ff989bf3d1b7c2999b8