Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Martin Empting"'
Autor:
Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infection in infants, older adults and the immunocompromised. Effective directly acting antivirals are not yet available for clinical use. To address this,
Externí odkaz:
https://doaj.org/article/66d08a2bbc3740f4a9e811166d229bd4
Autor:
Shilpee Chanda, Konstantin Lepikhov, Charlotte Dahlem, Hanna S. Schymik, Jessica Hoppstädter, An-Kristin Geber, Konrad Wagner, Sonja M. Kessler, Martin Empting, Alexandra K. Kiemer
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 41 (2024)
Background: The RNA-binding protein IGF2BP2/IMP2/VICKZ2/p62 is an oncofetal protein that is overexpressed in several cancer entities. Employing IMP2 knockout colorectal cancer cells, we could show the important role of IMP2 in several hallmarks of ca
Externí odkaz:
https://doaj.org/article/89d6e122b66b49bd99ed274709c6606a
Autor:
Christian Schütz, Duy‐Khiet Ho, Mostafa Mohamed Hamed, Ahmed Saad Abdelsamie, Teresa Röhrig, Christian Herr, Andreas Martin Kany, Katharina Rox, Stefan Schmelz, Lorenz Siebenbürger, Marius Wirth, Carsten Börger, Samir Yahiaoui, Robert Bals, Andrea Scrima, Wulf Blankenfeldt, Justus Constantin Horstmann, Rebekka Christmann, Xabier Murgia, Marcus Koch, Aylin Berwanger, Brigitta Loretz, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Claus‐Michael Lehr, Martin Empting
Publikováno v:
Advanced Science, Vol 8, Iss 12, Pp n/a-n/a (2021)
Abstract Pseudomonas aeruginosa (PA) infections can be notoriously difficult to treat and are often accompanied by the development of antimicrobial resistance (AMR). Quorum sensing inhibitors (QSI) acting on PqsR (MvfR) – a crucial transcriptional
Externí odkaz:
https://doaj.org/article/e48e16d2f7b2409bac151ac65a104396
Autor:
Christian Schütz, Martin Empting
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2627-2645 (2018)
The Gram-negative opportunistic pathogen Pseudomonas aeruginosa causes severe nosocomial infections. It uses quorum sensing (QS) to regulate and coordinate population-wide group behaviours in the infection process like concerted secretion of virulenc
Externí odkaz:
https://doaj.org/article/6871c7daea9843ccbffb3aa1244818f7
Autor:
Giuseppe Allegretta, Christine K. Maurer, Jens Eberhard, Damien Maura, Rolf W. Hartmann, Laurence Rahme, Martin Empting
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Pseudomonas aeruginosa is a Gram-negative bacterium, which causes opportunistic infections in immuno-compromised individuals. Due to its multiple resistances toward antibiotics, the development of new drugs is required. Interfering with Quorum Sensin
Externí odkaz:
https://doaj.org/article/9c7fffecdf724a0497e57d75b984355f
Autor:
Christian Schmitt, Dagmar Kail, Marica Mariano, Martin Empting, Nadja Weber, Tamara Paul, Rolf W Hartmann, Matthias Engel
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e87851 (2014)
The Dyrk family of protein kinases is implicated in the pathogenesis of several diseases, including cancer and neurodegeneration. Pharmacological inhibitors were mainly described for Dyrk1A so far, but in fewer cases for Dyrk1B, Dyrk2 or other isofor
Externí odkaz:
https://doaj.org/article/1f56fdf395384a9ab380c4b85fedbd56
Autor:
Martin Empting, Volkmar Braun, Dieter Jahn, Mathias Hornef, Daniela Kruck, Jürgen Lassak, Johannes Sander, Anett Schallmey, Daniel B. Eckl
Publikováno v:
BIOspektrum. 29:166-171
Autor:
Giuseppe Allegretta, Christine K. Maurer, Jens Eberhard, Damien Maura, Rolf W. Hartmann, Laurence Rahme, Martin Empting
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Pseudomonas aeruginosa is a Gram-negative bacterium, which causes opportunistic infections in immuno-compromised individuals. Due to its multiple resistances toward antibiotics, the development of new drugs is required. Interfering with Quorum Sensin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889c055998baaafeddfda59200ee919a
Autor:
Justus C. Horstmann, Annabelle Laric, Annette Boese, Daniela Yildiz, Teresa Röhrig, Martin Empting, Nicolas Frank, Daniel Krug, Rolf Müller, Nicole Schneider-Daum, Cristiane de Souza Carvalho-Wodarz, Claus-Michael Lehr
Publikováno v:
ACS Infectious Diseases. 8:137-149
Autor:
Valentin Jakob, Ben G.E. Zoller, Julia Rinkes, Yingwen Wu, Alexander F. Kiefer, Michael Hust, Saskia Polten, Andrew M. White, Peta J. Harvey, Thomas Durek, David J. Craik, Andreas Siebert, Uli Kazmaier, Martin Empting
Small macrocyclic peptides are promising candidates for new anti-infective drugs. To date, such peptides have been poorly studied in the context of anti-virulence targets. Using phage display and a self-designed peptide library, we identified a cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e738afb2fdc11b9e7e791db3ccd0a1b