Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Martin Empting"'
Autor:
Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infection in infants, older adults and the immunocompromised. Effective directly acting antivirals are not yet available for clinical use. To address this,
Externí odkaz:
https://doaj.org/article/66d08a2bbc3740f4a9e811166d229bd4
Autor:
Shilpee Chanda, Konstantin Lepikhov, Charlotte Dahlem, Hanna S. Schymik, Jessica Hoppstädter, An-Kristin Geber, Konrad Wagner, Sonja M. Kessler, Martin Empting, Alexandra K. Kiemer
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 41 (2024)
Background: The RNA-binding protein IGF2BP2/IMP2/VICKZ2/p62 is an oncofetal protein that is overexpressed in several cancer entities. Employing IMP2 knockout colorectal cancer cells, we could show the important role of IMP2 in several hallmarks of ca
Externí odkaz:
https://doaj.org/article/89d6e122b66b49bd99ed274709c6606a
Autor:
Christian Schütz, Duy‐Khiet Ho, Mostafa Mohamed Hamed, Ahmed Saad Abdelsamie, Teresa Röhrig, Christian Herr, Andreas Martin Kany, Katharina Rox, Stefan Schmelz, Lorenz Siebenbürger, Marius Wirth, Carsten Börger, Samir Yahiaoui, Robert Bals, Andrea Scrima, Wulf Blankenfeldt, Justus Constantin Horstmann, Rebekka Christmann, Xabier Murgia, Marcus Koch, Aylin Berwanger, Brigitta Loretz, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Claus‐Michael Lehr, Martin Empting
Publikováno v:
Advanced Science, Vol 8, Iss 12, Pp n/a-n/a (2021)
Abstract Pseudomonas aeruginosa (PA) infections can be notoriously difficult to treat and are often accompanied by the development of antimicrobial resistance (AMR). Quorum sensing inhibitors (QSI) acting on PqsR (MvfR) – a crucial transcriptional
Externí odkaz:
https://doaj.org/article/e48e16d2f7b2409bac151ac65a104396
Autor:
Martin Empting, Volkmar Braun, Dieter Jahn, Mathias Hornef, Daniela Kruck, Jürgen Lassak, Johannes Sander, Anett Schallmey, Daniel B. Eckl
Publikováno v:
BIOspektrum. 29:166-171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24660c12c708992d736c88945596d65f
https://doi.org/10.1007/s12268-023-1915-x
https://doi.org/10.1007/s12268-023-1915-x
Autor:
Christian Schütz, Martin Empting
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2627-2645 (2018)
The Gram-negative opportunistic pathogen Pseudomonas aeruginosa causes severe nosocomial infections. It uses quorum sensing (QS) to regulate and coordinate population-wide group behaviours in the infection process like concerted secretion of virulenc
Externí odkaz:
https://doaj.org/article/6871c7daea9843ccbffb3aa1244818f7
Autor:
Giuseppe Allegretta, Christine K. Maurer, Jens Eberhard, Damien Maura, Rolf W. Hartmann, Laurence Rahme, Martin Empting
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Pseudomonas aeruginosa is a Gram-negative bacterium, which causes opportunistic infections in immuno-compromised individuals. Due to its multiple resistances toward antibiotics, the development of new drugs is required. Interfering with Quorum Sensin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889c055998baaafeddfda59200ee919a
Autor:
Justus C. Horstmann, Annabelle Laric, Annette Boese, Daniela Yildiz, Teresa Röhrig, Martin Empting, Nicolas Frank, Daniel Krug, Rolf Müller, Nicole Schneider-Daum, Cristiane de Souza Carvalho-Wodarz, Claus-Michael Lehr
Publikováno v:
ACS Infectious Diseases. 8:137-149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c7745a1756ec5e0a6043b0eb657334e
https://doi.org/10.1021/acsinfecdis.1c00444
https://doi.org/10.1021/acsinfecdis.1c00444
Autor:
Valentin Jakob, Ben G.E. Zoller, Julia Rinkes, Yingwen Wu, Alexander F. Kiefer, Michael Hust, Saskia Polten, Andrew M. White, Peta J. Harvey, Thomas Durek, David J. Craik, Andreas Siebert, Uli Kazmaier, Martin Empting
Small macrocyclic peptides are promising candidates for new anti-infective drugs. To date, such peptides have been poorly studied in the context of anti-virulence targets. Using phage display and a self-designed peptide library, we identified a cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e738afb2fdc11b9e7e791db3ccd0a1b
Autor:
Svenja M. Sake, Christina Kosch, Sebastian Blockus, Sibylle Haid, Antonia P. Gunesch, Xiaoyu Zhang, Martina Friesland, Sofie B. Trummer, Christina Grethe, Anne Kühnel, Jessica Rückert, W. Paul Duprex, Jiabin Huang, Marie-Anne Rameix-Welti, Martin Empting, Nicole Fischer, Anna K. H. Hirsch, Thomas F. Schulz, Thomas Pietschmann
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 2022, 66 (12), ⟨10.1128/aac.01032-22⟩
Antimicrobial Agents and Chemotherapy, 2022, 66 (12), ⟨10.1128/aac.01032-22⟩
International audience; Human respiratory syncytial virus (hRSV) infection is a leading cause of severe respiratory tract infections. Effective, directly acting antivirals against hRSV are not available. We aimed to discover new and chemically divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17793939e21856df2d248a24962e93a5
https://pubmed.ncbi.nlm.nih.gov/36346232
https://pubmed.ncbi.nlm.nih.gov/36346232
Autor:
Carla F. Sousa, Mohamed A.M. Kamal, Robert Richter, Kalanika Elamaldeniya, Rolf W. Hartmann, Martin Empting, Claus-Michael Lehr, Olga V. Kalinina
Publikováno v:
Journal of chemical information and modeling. 62(20)
Passive diffusion across biomembranes is an important mechanism of permeation for multiple drugs, including antibiotics. However, this process is frequently neglected while studying drug uptake and, in our view, warrants further investigation. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6d3d6869117b96ca92190c0b39ed5e
https://pubmed.ncbi.nlm.nih.gov/36214845
https://pubmed.ncbi.nlm.nih.gov/36214845