Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Martin Elmlinger"'
Autor:
Stefan Röpcke, Olaf Holz, Gereon Lauer, Meike Müller, Susanne Rittinghausen, Peter Ernst, Gezim Lahu, Martin Elmlinger, Norbert Krug, Jens M Hohlfeld
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46207 (2012)
Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory disease, primarily affecting the airways. Stable biomarkers characterizing the inflammatory phenotype of the disease, relevant for disease activity and suited to predict disease p
Externí odkaz:
https://doaj.org/article/08ee681f45314d08b95fa3da8fa61590
Publikováno v:
Journal of Cellular and Molecular Medicine
This study aimed to investigate whether Actovegin, which is a deproteinized ultrafiltrate derived from calf blood, demonstrates neuroprotective effects in a rat model of transient global cerebral ischaemia. Forty Sprague Dawley rats were subjected to
Publikováno v:
Neuromolecular Medicine
The recently described therapeutic benefits of the hemodialysate actovegin on neuropathic symptoms in diabetic patients with symptomatic polyneuropathy suggest a neuroprotective activity of the drug. To elucidate the possible cellular mechanism of th
Autor:
Florian Buchmayer, Gereon Lauer, Gerfried Nell, Martin Elmlinger, Harald H. Sitte, Johannes Pleiner
Publikováno v:
Wiener Medizinische Wochenschrift. 161:80-88
Actovegin(®) is a biological drug manufactured from a natural source: it is a calf blood hemodialysate. Its therapeutic benefits stem from a variety of pharmacodynamic actions that can be summarized to a common goal, i.e. the enhancement of cellular
Autor:
Martin Elmlinger, Edgar Diletti, Karl Zech, Gezim Lahu, Axel Facius, Andreas Hünnemeyer, Nigel McCracken, Peter Ruth
Publikováno v:
Clinical Pharmacokinetics. 49:589-606
Roflumilast is an oral, selective phosphodiesterase (PDE)-4 inhibitor in development for the treatment of chronic obstructive pulmonary disease (COPD). Both roflumilast and its metabolite roflumilast N-oxide have anti-inflammatory properties that con
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 120(3)
Diabetic neuropathy is one of the most severe complications of diabetes, affecting approximately one-third of diabetic patients. We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an
Autor:
Carla Winkler, Veit J. Erpenbeck, Michael F. Beers, Jens M. Hohlfeld, Elena N. Atochina-Vasserman, Gereon Lauer, Norbert Krug, Martin Elmlinger, Olaf Holz, Stefan Roepcke
Publikováno v:
Respiratory Research
Respiratory Research, Vol 12, Iss 1, p 29 (2011)
Respiratory Research, Vol 12, Iss 1, p 29 (2011)
Background Pulmonary surfactant protein D (SP-D) is considered as a candidate biomarker for the functional integrity of the lung and for disease progression, which can be detected in serum. The origin of SP-D in serum and how serum concentrations are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5769fa3b41e4d72baa715f42e470fb3
https://publica.fraunhofer.de/handle/publica/224564
https://publica.fraunhofer.de/handle/publica/224564
Autor:
Martin Elmlinger, Markus Hinder, Gezim Lahu, Nassr Nassr, Peter Ruth, Andreas Huennemeyer, Rolf Herzog
Publikováno v:
Journal of clinical pharmacology. 51(4)
Roflumilast is an oral phosphodiesterase 4 (PDE4) inhibitor for the treatment of chronic obstructive pulmonary disease (COPD). It is metabolized by CYP1A2 and CYP3A4 to its primary metabolite, roflumilast N-oxide, through which >90% total PDE4 inhibi
Autor:
Stefan, Hiendleder, Michaela, Wirtz, Cora, Mund, Martina, Klempt, Horst-Dieter, Reichenbach, Miodrag, Stojkovic, Myriam, Weppert, Hendrik, Wenigerkind, Martin, Elmlinger, Frank, Lyko, Oliver J, Schmitz, Eckhard, Wolf
Publikováno v:
Biology of reproduction. 75(1)
Epigenetic perturbations are assumed to be responsible for phenotypic abnormalities of fetuses and offspring originating from in vitro embryo techniques. We studied 29 viable Day-80 bovine fetuses to assess the effects of two in vitro fertilization p
Autor:
Gezim Lahu, Meike Müller, Olaf Holz, Peter B. Ernst, Stefan Röpcke, Norbert Krug, Martin Elmlinger, Gereon Lauer, Jens M. Hohlfeld, Susanne Rittinghausen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e46207 (2012)
PLoS ONE, Vol 7, Iss 10, p e46207 (2012)
Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory disease, primarily affecting the airways. Stable biomarkers characterizing the inflammatory phenotype of the disease, relevant for disease activity and suited to predict disease p