Zobrazeno 1 - 10
of 422
pro vyhledávání: '"Martin E Schwab"'
Autor:
Michèle Hubli, Luca Regli, Anna-Sophie Hofer, Armin Curt, Martin Schubert, Thomas M Kessler, Christian R Baumann, Christian Meyer, Lennart H Stieglitz, Marc Bolliger, Markus F Oertel, Linard Filli, Romina Willi, Adrian Cathomen, Lukas Imbach, Iris Krüsi, Andrea Prusse, Martin E Schwab
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Introduction Spinal cord injury (SCI) is a devastating condition with immediate impact on the individual’s health and quality of life. Major functional recovery reaches a plateau 3–4 months after injury despite intensive rehabilitative training.
Externí odkaz:
https://doaj.org/article/8d69360b86b7471d8af0881cca7d3a7b
Autor:
Jörg H Stehle, Zhiyuan Sheng, Laura Hausmann, Philipp Bechstein, Oliver Weinmann, Juha Hernesniemi, Joseph S Neimat, Martin E Schwab, Ajmal Zemmar
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250743 (2021)
The adult, mature central nervous system (CNS) has limited plasticity. Physical exercising can counteract this limitation by inducing plasticity and fostering processes such as learning, memory consolidation and formation. Little is known about the m
Externí odkaz:
https://doaj.org/article/30b820d43428430092ca39325d1a50cc
Autor:
Pierfrancesco Pagella, Chai Foong Lai, Laurence Pirenne, Claudio Cantù, Martin E. Schwab, Thimios A. Mitsiadis
Publikováno v:
International Journal of Oral Science, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Neurite outgrowth inhibitor A (Nogo-A) is a major player in neural development and regeneration and the target of clinical trials aiming at promoting the regeneration of the central nervous system upon traumatic and ischemic injury. In this
Externí odkaz:
https://doaj.org/article/7a38e332226d460cab7be7e913df6316
Autor:
Stewart Berry, Oliver Weinmann, Ann-Kristina Fritz, Ruslan Rust, David Wolfer, Martin E Schwab, Urs Gerber, Jeanne Ster
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200896 (2018)
Recent investigations of Nogo-A, a well characterized protein inhibitor of neurite outgrowth in the brain, have revealed additional functions including a role in neuropsychiatric disorders such as schizophrenia. Here we examined Nogo-A functions in m
Externí odkaz:
https://doaj.org/article/d5dc40e5570b4ea19fe32fa070309203
Autor:
Linard Filli, Martin E Schwab
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 4, Pp 509-513 (2015)
Axonal regeneration and fiber regrowth is limited in the adult central nervous system, but research over the last decades has revealed a high intrinsic capacity of brain and spinal cord circuits to adapt and reorganize after smaller injuries or dener
Externí odkaz:
https://doaj.org/article/0b1005ba94aa401db6ba551352eba924
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161813 (2016)
Functional recovery from central neurotrauma, such as spinal cord injury, is limited by myelin-associated inhibitory proteins. The most prominent example, Nogo-A, imposes an inhibitory cue for nerve fibre growth via two independent domains: Nogo-A-Δ
Externí odkaz:
https://doaj.org/article/e8264f5d08d14181bc774893911e870c
Autor:
Tomas ePetrasek, Iva eProkopova, Martin eSladek, Kamila eWeissova, Iveta eVojtechova, Štěpán eBahník, Anna eZemanova, Kai eSchonig, Stefan eBerger, Bjorn eTews, Dusan eBartsch, Martin E Schwab, Alena eSumova, Ales eStuchlik
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Externí odkaz:
https://doaj.org/article/b601541b9eac492696e9505473d1fd49
Autor:
Anissa Kempf, Bjoern Tews, Michael E Arzt, Oliver Weinmann, Franz J Obermair, Vincent Pernet, Marta Zagrebelsky, Andrea Delekate, Cristina Iobbi, Ajmal Zemmar, Zorica Ristic, Miriam Gullo, Peter Spies, Dana Dodd, Daniel Gygax, Martin Korte, Martin E Schwab
Publikováno v:
PLoS Biology, Vol 12, Iss 1, p e1001763 (2014)
Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20. Receptors transducing Nogo-A-Δ20 signaling remained elusive so far. Here we i
Externí odkaz:
https://doaj.org/article/bf0435eb427c4707b9e3fffb96f095d4
Autor:
Richard Manns, Andre Schmandke, Antonio Schmandke, Prem Jareonsettasin, Geoffrey Cook, Martin E Schwab, Christine Holt, Roger Keynes
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86820 (2014)
The protein Nogo-A regulates axon growth in the developing and mature nervous system, and this is carried out by two distinct domains in the protein, Nogo-A-Δ20 and Nogo-66. The differences in the signalling pathways engaged in axon growth cones by
Externí odkaz:
https://doaj.org/article/b14b80fcda314c738cc6bc35495e3ef2
Autor:
Florence eHoogewoud, Adjia eHamadjida, Alexander Felix Wyss, Anis eMir, Martin E Schwab, Abderraouf eBelhaj-Saif, Eric M. Rouiller
Publikováno v:
Frontiers in Neurology, Vol 4 (2013)
In relation to mechanisms involved in functional recovery of manual dexterity from cervical cord injury or from motor cortical injury, our goal was to determine whether the movements that characterize post-lesion functional recovery are comparable to
Externí odkaz:
https://doaj.org/article/07bded44a8c443c48dddb85af0b3dcd9