Zobrazeno 1 - 10
of 556
pro vyhledávání: '"Martin Dugas"'
Autor:
T. Elise Potthoff, Carolin Walter, Daniela Jeising, Daniel Münter, Archana Verma, Eric Suero Molina, Walter Stummer, Martin Dugas, Wolfgang Hartmann, Matthias Dottermusch, Lea Altendorf, Ulrich Schüller, Sophia Scheuermann, Christian Seitz, Thomas K. Albert, Kornelius Kerl
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Pituitary neuroendocrine tumors (PitNET) are among the most common intracranial tumors. Despite a frequent benign course, aggressive behavior can occur. Tumor behavior is known to be under the influence of the tumor microenvironme
Externí odkaz:
https://doaj.org/article/9d87dc91d88548038291cde05a5e76b8
Autor:
Anja Fischer, Thomas K. Albert, Natalia Moreno, Marta Interlandi, Jana Mormann, Selina Glaser, Paurnima Patil, Flavia W. de Faria, Mathis Richter, Archana Verma, Sebastian T. Balbach, Rabea Wagener, Susanne Bens, Sonja Dahlum, Carolin Göbel, Daniel Münter, Clara Inserte, Monika Graf, Eva Kremer, Viktoria Melcher, Gioia Di Stefano, Raffaella Santi, Alexander Chan, Ahmet Dogan, Jonathan Bush, Martin Hasselblatt, Sylvia Cheng, Signe Spetalen, Alexander Fosså, Wolfgang Hartmann, Heidi Herbrüggen, Stella Robert, Florian Oyen, Martin Dugas, Carolin Walter, Sarah Sandmann, Julian Varghese, Claudia Rossig, Ulrich Schüller, Alexandar Tzankov, Martin B. Pedersen, Francesco A. d’Amore, Karin Mellgren, Udo Kontny, Venkatesh Kancherla, Luis Veloza, Edoardo Missiaglia, Virginie Fataccioli, Philippe Gaulard, Birgit Burkhardt, Oliver Soehnlein, Wolfram Klapper, Laurence de Leval, Reiner Siebert, Kornelius Kerl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous group of malignancies with poor outcome. Here, we identify a subgroup, PTCL-NOS SMARCB1- , which is characterized by the lack of the SMARCB1 protein and occurs
Externí odkaz:
https://doaj.org/article/f9838f5a5f15480799585f8fa2420a7e
Autor:
Martin Dugas, Max Blumenstock, Tobias Dittrich, Urs Eisenmann, Stephan Christoph Feder, Fleur Fritz-Kebede, Lucy J. Kessler, Maximilian Klass, Petra Knaup, Christoph U. Lehmann, Angela Merzweiler, Christian Niklas, Thomas M. Pausch, Nelly Zental, Matthias Ganzinger
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Structured patient data play a key role in all types of clinical research. They are often collected in study databases for research purposes. In order to describe characteristics of a next-generation study database and assess the feasibility
Externí odkaz:
https://doaj.org/article/ff4941fceba6475197fa4d0d176acfa2
Autor:
Johannes Benedict Oehm, Sarah Luise Riepenhausen, Michael Storck, Martin Dugas, Rüdiger Pryss, Julian Varghese
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e47846 (2024)
BackgroundThe Network University Medicine projects are an important part of the German COVID-19 research infrastructure. They comprise 2 subprojects: COVID-19 Data Exchange (CODEX) and Coordination on Mobile Pandemic Apps Best Practice and Solution S
Externí odkaz:
https://doaj.org/article/34bb06ab34f54c77ae46895be52a6768
Autor:
Lisa Zipper, Rabea Wagener, Ute Fischer, Anna Hoffmann, Layal Yasin, Danielle Brandes, Stavrieta Soura, Ammarah Anwar, Carolin Walter, Julian Varghese, Julia Hauer, Franziska Auer, Sanil Bhatia, Martin Dugas, Stefanie V. Junk, Martin Stanulla, Oskar A. Haas, Arndt Borkhardt, Tobias Reiff, Triantafyllia Brozou
Publikováno v:
HemaSphere, Vol 8, Iss 1, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/bf1493960537425bbd60e7eed04ac8bb
Autor:
Fabio Efficace, Karin Koinig, Francesco Cottone, David Bowen, Moshe Mittelman, Kathrin Sommer, Saskia Langemeijer, Dominic Culligan, Kalman Filanovsky, Michael Storck, Alexandra Smith, Corine van Marrewijk, Martin Dugas, Igor Stojkov, Uwe Siebert, Theo de Witte, Reinhard Stauder
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 7529-7539 (2023)
Abstract Background Clinical decision‐making for patients with myelodysplastic syndromes (MDS) is challenging, and both disease and treatment effects heavily impact health‐related quality of life (HRQoL) of these patients. Therefore, disease‐sp
Externí odkaz:
https://doaj.org/article/9588dc2ae971409c99ea1d55ddd9ae0c
Autor:
Annika Bürger, Martin Dugas
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Genetic and epigenetic biological studies often combine different types of experiments and multiple conditions. While the corresponding raw and processed data are made available through specialized public databases, the processed
Externí odkaz:
https://doaj.org/article/e14e18fceebc43a4a451b7daeb5f136c
Autor:
Birgit Burkhardt, Ulf Michgehl, Jonas Rohde, Tabea Erdmann, Philipp Berning, Katrin Reutter, Marius Rohde, Arndt Borkhardt, Thomas Burmeister, Sandeep Dave, Alexandar Tzankov, Martin Dugas, Sarah Sandmann, Falko Fend, Jasmin Finger, Stephanie Mueller, Nicola Gökbuget, Torsten Haferlach, Wolfgang Kern, Wolfgang Hartmann, Wolfram Klapper, Ilske Oschlies, Julia Richter, Udo Kontny, Mathias Lutz, Britta Maecker-Kolhoff, German Ott, Andreas Rosenwald, Reiner Siebert, Arend von Stackelberg, Brigitte Strahm, Wilhelm Woessmann, Martin Zimmermann, Myroslav Zapukhlyak, Michael Grau, Georg Lenz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Survival outcomes in Burkitt lymphoma differ between adult and paediatric patients. Here, the authors show differences in mutational frequencies between age groups, and a transition between mutational profiles which occurs between 25 and 40 years.
Externí odkaz:
https://doaj.org/article/23e93bbbffce48e295f023de9062df49
Autor:
Ahmed Rafee, Sarah Riepenhausen, Philipp Neuhaus, Alexandra Meidt, Martin Dugas, Julian Varghese
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Screening for eligible patients continues to pose a great challenge for many clinical trials. This has led to a rapidly growing interest in standardizing computable representations of eligibility criteria (EC) in order to develop
Externí odkaz:
https://doaj.org/article/902e01a724db4dc681cb573b6943501d
Autor:
Monika Graf, Marta Interlandi, Natalia Moreno, Dörthe Holdhof, Carolin Göbel, Viktoria Melcher, Julius Mertins, Thomas K. Albert, Dennis Kastrati, Amelie Alfert, Till Holsten, Flavia de Faria, Michael Meisterernst, Claudia Rossig, Monika Warmuth-Metz, Johannes Nowak, Gerd Meyer zu Hörste, Chloe Mayère, Serge Nef, Pascal Johann, Michael C. Frühwald, Martin Dugas, Ulrich Schüller, Kornelius Kerl
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Rhabdoid tumors (RT) are aggressive paediatric cancers with yet unknown cells of origin. Here, the authors establish genetically engineered mouse models of RT and, using single-cell RNA-seq and epigenomics, identify potential cells of origin for the
Externí odkaz:
https://doaj.org/article/124e1a551f524ef8bfe6f35ccde842d8