Absolute and Relative Psoriasis Area and Severity Indices (PASI) for Comparison of the Efficacy of Ixekizumab to Etanercept and Placebo in Patients with Moderate-to-severe Plaque Psoriasis: An Integrated Analysis of UNCOVER-2 and UNCOVER-3 Outcomes

Autor: Luís Puig, Martin Dossenbach, Lovisa Berggren, Anders Ljungberg, Claus Zachariae

Publikováno v: Acta Dermato-Venereologica, Vol 99, Iss 11, Pp 971-977 (2019)

Treatment goals defined by the absolute Psoriasis Area and Severity Index (PASI) scores offer certain advantages in the clinical setting. In order to investigate potential treatment targets, this study evaluated absolute PASI outcomes relative to oth

Externí odkaz: https://doaj.org/article/a1b77587a01346cd87a844f421c5cb4c

Network meta‐analysis of biologic treatments for psoriasis using absolute Psoriasis Area and Severity Index values ≤1, 2, 3 or 5 derived from a statistical conversion method

Autor: S Hartz, Kristian Reich, Ulrich Mrowietz, Craig L. Leonardi, Martin Dossenbach, Helmut Petto, Richard B. Warren, Daniel Saure

Publikováno v: Journal of the European Academy of Dermatology and Venereology

Background In practice, the goal of treatment for patients with psoriasis is to achieve almost clear or clear skin and maintain disease control, regardless of baseline disease severity. However, identifying absolute Psoriasis Area and Severity Index

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb11085e1d9fad49d1d88160ac2b9eb
https://doi.org/10.1111/jdv.17130

Absolute and Relative Psoriasis Area and Severity Indices (PASI) for Comparison of the Efficacy of Ixekizumab to Etanercept and Placebo in Patients with Moderate-to-severe Plaque Psoriasis: An Integrated Analysis of UNCOVER-2 and UNCOVER-3 Outcomes

Autor: Lovisa Berggren, Anders Ljungberg, Martin Dossenbach, Claus Zachariae, Luis Puig

Publikováno v: Acta Dermato-Venereologica, Vol 99, Iss 11, Pp 971-977 (2019)
Puig, L, Dossenbach, M, Berggren, L, Ljungberg, A & Zachariae, C 2019, ' Absolute and Relative Psoriasis Area and Severity Indices (PASI) for Comparison of the Efficacy of Ixekizumab to Etanercept and Placebo in Patients with Moderate-to-severe Plaque Psoriasis : An Integrated Analysis of UNCOVER-2 and UNCOVER-3 Outcomes ', Acta Dermato-Venereologica, vol. 99, no. 11, pp. 971-977 . https://doi.org/10.2340/00015555-3245
ACTA DERMATO-VENEREOLOGICA
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Treatment goals defined by the absolute Psoriasis Area and Severity Index (PASI) scores offer certain advantages in the clinical setting. In order to investigate potential treatment targets, this study evaluated absolute PASI outcomes relative to oth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ceee149a19f2336f0075aa7f36aea3
https://doaj.org/article/a1b77587a01346cd87a844f421c5cb4c

Indirect comparisons of ixekizumab versus three interleukin-23 p19 inhibitors in patients with moderate-to-severe plaque psoriasis - efficacy findings up to week 12

Autor: Diamant Thaçi, Stefan Wilhelm, Alice B. Gottlieb, Yuval Ramot, Martin Dossenbach, Saxon D Smith, Christopher Schuster, Daniel Saure

Publikováno v: The Journal of dermatological treatment. 33(1)

It is challenging to select the most appropriate biologic treatment for patients with moderate-to-severe plaque psoriasis. To compare speed of onset and level of skin improvement between the interleukin (IL)-17A antagonist ixekizumab and the IL-23 p1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855ca9c4fbde4da10d8656a37e1f4eb6
https://pubmed.ncbi.nlm.nih.gov/32299269

Impact of Ixekizumab Treatment on Itch and Psoriasis Area and Severity Index in Patients with Moderate-to-Severe Plaque Psoriasis: An Integrated Analysis of Two Phase III Randomized Studies

Autor: Thomas A. Luger, Anke Beselin, Adam Reich, Carsten Henneges, Lovisa Berggren, Gil Yosipovitch, Toby C. Kent, Martin Dossenbach, Martin Steinhoff

Publikováno v: Dermatology and Therapy, Vol 8, Iss 4, Pp 621-637 (2018)
Dermatology and Therapy

Introduction We evaluated baseline itch and its impact on the efficacy of ixekizumab (IXE) in clearing psoriasis and improving quality-of-life measures, and we explored the relationship between itch and psoriatic skin improvement. Methods Data were a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f467bda0ec0fc155108db101f31e0d0
http://link.springer.com/article/10.1007/s13555-018-0267-9