Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Martin D. Burkhalter"'
Autor:
Martin D. Burkhalter, Tom Stiff, Lars D. Maerz, Teresa Casar Tena, Heike Wiese, Julian Gerhards, Steffen A. Sailer, Linh Anna Trúc Vu, Max Duong Phu, Cornelia Donow, Marius Alupei, Sebastian Iben, Marco Groth, Sebastian Wiese, Joseph A. Church, Penelope A. Jeggo, Melanie Philipp
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-14 (2024)
Abstract The WD repeat-containing protein 4 (WDR4) has repeatedly been associated with primary microcephaly, a condition of impaired brain and skull growth. Often, faulty centrosomes cause microcephaly, yet aberrant cilia may also be involved. Here,
Externí odkaz:
https://doaj.org/article/c7c8e616bb0a44d686f248d5e16d846c
Autor:
Swagata Halder, Ignacio Torrecilla, Martin D. Burkhalter, Marta Popović, John Fielden, Bruno Vaz, Judith Oehler, Domenic Pilger, Davor Lessel, Katherine Wiseman, Abhay Narayan Singh, Iolanda Vendrell, Roman Fischer, Melanie Philipp, Kristijan Ramadan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Cells deficient in SPRTN protease activity exhibit severe DNA-protein crosslink induced replication stress and genome instability. Here the author reveal a functional link between the SPRTN protease and the CHK1 kinase during physiological DNA replic
Externí odkaz:
https://doaj.org/article/21ed31bb8358406db2dcfaaf5eadcf04
Publikováno v:
Cell Reports, Vol 4, Iss 4, Pp 625-632 (2013)
The correct asymmetric placement of inner organs is termed situs solitus and is determined early during development. Failure in symmetry breaking results in conditions ranging from randomized organ arrangement to a complete mirror image, often accomp
Externí odkaz:
https://doaj.org/article/cff886e2f38e4af3b07154f01d6938ba
Autor:
Ilaria Dutto, Julian Gerhards, Antonio Herrera, Olga Souckova, Václava Škopová, Jordann A Smak, Alexandra Junza, Oscar Yanes, Cedric Boeckx, Martin D Burkhalter, Marie Zikánová, Sebastian Pons, Melanie Philipp, Jens Lüders, Travis H Stracker
Publikováno v:
eLife, Vol 11 (2022)
Adenylosuccinate lyase (ADSL) functions in de novo purine synthesis (DNPS) and the purine nucleotide cycle. ADSL deficiency (ADSLD) causes numerous neurodevelopmental pathologies, including microcephaly and autism spectrum disorder. ADSLD patients ha
Externí odkaz:
https://doaj.org/article/5ef7d8baa9df4de681a7f4e9f3e46c1a
Autor:
Julian Gerhards, Lars D. Maerz, Edda S. F. Matthees, Cornelia Donow, Barbara Moepps, Richard T. Premont, Martin D. Burkhalter, Carsten Hoffmann, Melanie Philipp
Publikováno v:
Journal of the American Society of Nephrology. 34:590-606
Publikováno v:
Biology of the Cell. 114:143-159
Improper expansion of neural stem and progenitor cells during brain development manifests in primary microcephaly. This disease is characterized by a reduced head circumference, which correlates with a reduction in brain size. This often corresponds
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031215469
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0b35412786d87bcc9ad59aeb14d8f6b
https://doi.org/10.1007/978-3-031-21547-6_4
https://doi.org/10.1007/978-3-031-21547-6_4
Autor:
Julian Gerhards, Ilaria Dutto, Antonio Herrera, Olga Souckova, Václava Škopová, Jordann A Smak, Alexandra Junza, Oscar Yanes, Cedric Boeckx, Martin D Burkhalter, Marie Zikánová, Sebastian Pons, Melanie Philipp, Jens Lüders, Travis H Stracker
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Adenylosuccinate lyase (ADSL) functions in de novo purine synthesis (DNPS) and the purine nucleotide cycle. ADSL deficiency (ADSLD) causes numerous neurodevelopmental pathologies, including microcephaly and autism spectrum disorder. ADSLD patients ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e3b1e33aefea47060e8952e6a4c97e
http://hdl.handle.net/10261/281196
http://hdl.handle.net/10261/281196
Autor:
Martin D. Burkhalter, Marco Groth, Friedrich Becker, Yohei Morita, Hans A. Kestler, Sarah E. von Löhneysen, Ali H. Baig, Alush I. Avila, Melanie Philipp, Annika Scheffold, Johann M. Kraus, Stephan Stilgenbauer, André Lechel, Florian Schmid, Zhiyang Chen
Publikováno v:
Leukemia
Accumulation of DNA damage and myeloid-skewed differentiation characterize aging of the hematopoietic system, yet underlying mechanisms remain incompletely understood. Here, we show that aging hematopoietic progenitor cells particularly of the myeloi
Autor:
Julian Gerhards, Ilaria Dutto, Antonio Herrera, Olga Souckova, Václava Škopová, Jordann A Smak, Alexandra Junza, Oscar Yanes, Cedric Boeckx, Martin D Burkhalter, Marie Zikánová, Sebastian Pons, Melanie Philipp, Jens Lüders, Travis H Stracker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::666ccb4f65769523f493da8a18681b83
https://doi.org/10.7554/elife.70518.sa2
https://doi.org/10.7554/elife.70518.sa2