Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Martin D. Altschuler"'
Publikováno v:
Physics in Medicine and Biology. 53:4107-4121
The three-dimensional (3D) heterogeneous distributions of optical properties in a patient prostate can now be measured in vivo. Such data can be used to obtain a more accurate light-fluence kernel. (For specified sources and points, the kernel gives
Publikováno v:
Proceedings of SPIE--the International Society for Optical Engineering. 5689
To deliver uniform photodynamic dose to the prostate gland, it is necessary to develop algorithms that optimize the location and strength (emitted power × illumination time) of each light source. Since tissue optical properties may change with time,
Autor:
Stephen M. Hahn, Keith A. Cengel, Martin D. Altschuler, Jarod C. Finlay, Yida Hu, Timothy C. Zhu, Ken Wang, Andreea Dimofte
Publikováno v:
Proceedings of SPIE--the International Society for Optical Engineering. 7551
Singlet oxygen (1O2) is the major cytotoxic agent for type II photodynamic therapy (PDT). The production of 1O2 involves the complex reactions among light, oxygen molecule, and photosensitizer. From universal macroscopic kinetic equations which descr
Publikováno v:
Medical Physics. 32:3524-3536
The primary aim of this study was to determine whether optimized photodynamic therapy(PDT) treatment planning (seeking optimized positions, lengths, and strengths of the light sources to satisfy a given dose prescription) can improve dose coverage to
Autor:
Rex Cheung, Richard Whittington, Martin D. Altschuler, Anthony V. D'Amico, S. Bruce Malkowicz, Alan J. Wein
Publikováno v:
Urology. 57:286-290
Objectives. Rational treatment decision requires accurate projection of the clinical course of a patient. Current methods in clinical outcome analysis mostly focus on population data. We investigated the applicability and optimization of the widely u
A quality assurance device for the accuracy of the isocentres of teletherapy and simulation machines
Autor:
Bijan Arjomandy, Martin D. Altschuler
Publikováno v:
Physics in Medicine and Biology. 45:2207-2217
A new quality assurance device has been designed to measure the location and wobble of the radiation isocentre of linacs and simulation machines as a function of gantry rotation. The radiation isocentre is the intersection in space of the central x r
Autor:
Alireza Kassaee, Martin D. Altschuler
Publikováno v:
Medical Physics. 21:643-650
A difficult, error-prone, and time consuming problem in brachytherapy is the determination of the three-dimensional (3-D) positions of implanted seeds. To triangulate 3-D seed positions, the corresponding seed images in radiographs taken at different
Publikováno v:
Radiation Oncology Investigations. 1:235-248
For clinical cases with difficult combinations of patient parameter values, treatment selection may be complex or controversial and require considerable time. Treatment selection may be affected by a clinician's experience with a disease and expertis
Publikováno v:
Physics in Medicine and Biology. 37:391-411
A new method has been implemented to calculate rapidly and accurately the three-dimensional dose distribution induced in a heterogeneous volume by one or more electron and/or photon beams. The algorithm is based on the pre-calculation by Monte Carlo
Autor:
Jarod C. Finlay, Timothy C. Zhu, Martin D. Altschuler, Andreea Dimofte, Stephen M. Hahn, Yida Hu, Keith A. Cengel, Jun Li, Ken Wang, S. B. Malkowicz
Publikováno v:
SPIE Proceedings.
The object of this study is to develop optimization procedures that account for both the optical heterogeneity as well as photosensitizer (PS) drug distribution of the patient prostate and thereby enable delivery of uniform photodynamic dose to that