Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Martin D Knolle"'
Autor:
Darrel P Francis, Michael Brown, Nicholas J Matheson, Grant D Stewart, Jane Greenaway, Nick G Cunniffe, Simon J Gunter, Sarah W Burge, Tom Dymond, Hanif Esmail, Jacqui Galloway, Effrossyni Gkrania-Klotsas, George Katritsis, Martin D Knolle, Kelly Leonard, Zoe C McIntyre, Ben Prudon, Tommy Rampling, Mili Estee Torok, Ben Warne, Mark Yates, Sofia Villar
Publikováno v:
BMJ Open, Vol 10, Iss 10 (2020)
Objectives To analyse enrolment to interventional trials during the first wave of the COVID-19 pandemic in England and describe the barriers to successful recruitment in the circumstance of a further wave or future pandemics.Design We analysed regist
Externí odkaz:
https://doaj.org/article/9aa77797e2424303a05fbcb0e47a38f3
Autor:
Aydan C. H. Szeto, Ana C. F. Ferreira, Jonathan Mannion, Paula A. Clark, Meera Sivasubramaniam, Morgan W. D. Heycock, Alastair Crisp, Helen E. Jolin, Patrycja Kozik, Martin D. Knolle, Andrew N. J. McKenzie
Publikováno v:
Nature Immunology. 24:123-135
Naive CD4+ T lymphocytes initially undergo antigen-specific activation to promote a broad-spectrum response before adopting bespoke cytokine expression profiles shaped by intercellular microenvironmental cues, resulting in pathogen-focused modular cy
Autor:
Martin D. Knolle, Shau Bing Chin, Batika M. J. Rana, Alexandros Englezakis, Rinako Nakagawa, Padraic G. Fallon, Anna Git, Andrew N. J. McKenzie
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Group-2 innate lymphoid cells (ILC2) play critical roles in the initiation and maintenance of type-2 immune responses, predominantly through their production of the type-2 cytokines IL-5, IL-9, and IL-13. ILC2 are essential for the efficient eliminat
Externí odkaz:
https://doaj.org/article/e75d7c8cf6e14c20bf252f07e4d13696
Autor:
Sumit Karia, Stefan J. Marciniak, Maria Ta Wetscherek, Allanah Barker, Simon Holden, Martin D. Knolle, Judith Babar, Eamonn R. Maher, Hannah Lee Grimes, Jurgen Herre
Publikováno v:
Thorax
Familial spontaneous pneumothorax (FSP) accounts for 10% of primary spontaneous pneumothoraces. Appropriate investigation of FSP enables early diagnosis of serious monogenic diseases and the practice of precision medicine. Here, we show that a pneumo
Publikováno v:
Interventional pulmonology.
Autor:
Aydan C H, Szeto, Ana C F, Ferreira, Jonathan, Mannion, Paula A, Clark, Meera, Sivasubramaniam, Morgan W D, Heycock, Alastair, Crisp, Helen E, Jolin, Patrycja, Kozik, Martin D, Knolle, Andrew N J, McKenzie
Publikováno v:
Nature immunology. 24(1)
Naive CD4
Autor:
Li Su, Simon J Gunter, Effrossyni Gkrania-Klotsas, Kelly Leonard, Nicholas J Matheson, Darrel P. Francis, Mark Yates, Jane Greenaway, Anthony De Soyza, M. E. Török, Mark Toshner, Prapa Kanagaratnam, Ben Prudon, Ben Warne, George Katritsis, Grant D. Stewart, Michael Brown, Nick G Cunniffe, Zoe McIntyre, James Galloway, Sarah W. Burge, Tommy Rampling, Sofia S. Villar, Hanif Esmail, Clare Coyle, Jacqui Galloway, Tom Dymond, Martin D Knolle
Publikováno v:
BMJ Open
BMJ Open, Vol 10, Iss 10 (2020)
BMJ Open, Vol 10, Iss 10 (2020)
ObjectivesTo analyse enrolment to interventional trials during the first wave of the COVID-19 pandemic in England and describe the barriers to successful recruitment in the circumstance of a further wave or future pandemics.DesignWe analysed register
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45007b4b18c700210a2aca2efe10ec0
https://www.repository.cam.ac.uk/handle/1810/311169
https://www.repository.cam.ac.uk/handle/1810/311169
Autor:
Huw Steven Jenkins, Tom McLellan, Muhunthan Thillai, Chinmay Patvardhan, Martin D. Knolle, Doris Rassl
Publikováno v:
Thorax. 76(7)
A man in his 30s, with a history of mild childhood asthma only, went to his local hospital with difficulty in breathing. His presentation was preceded by 6 days of worsening breathlessness, wheeze and cough. He had been using his mother’s salbutamo
Publikováno v:
Malignant pleural disease.
Background Medical thoracoscopy (MT) is the gold standard investigation for exudative pleural effusions of cryptic origin. A diagnosis of non-specific pleuritis (NSP) however has unclear long-term outcomes, with some NSP patients harbouring occult me
Autor:
Sumit Karia, D Brown, Martin D. Knolle, Stefan J. Marciniak, Judith Babar, Hannah Lee Grimes, Eamonn R. Maher, Simon Holden, Jurgen Herre
Publikováno v:
Pleural disease: not so benign.
Background Spontaneous pneumothorax can be the presenting feature of several genetic disorders including Birt-Hogg-Dube, Marfan, and vascular Ehlers-Danlos syndromes. Diagnosing these conditions enables personalised management that can prolong life f