Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial

Autor: Sora Ludwig, Melissa Deans, Stacey Lacerte, Catherine Young, Kellie E. Murphy, J. Johanna Sanchez, Peter Subrt, David Thompson, Kayla Schutt, George Carson, Bernard Zinman, Thomas Ransom, Melanie Robinson, Minnie Parsons, Shirley Beauchamp, Darlene Baxendale, Afshan Zahedi, Richard Phillips, Natasha Garfield, Paul Karanicolas, Jason Kong, Adriana Breen, Agnieszka Barts, Vincent Wong, Elizabeth Asztalos, Jon Barrett, Heather Belanger, Bonnie Stone-Hope, Josee Champagne, Julie Lambert, Myriam Bouchard, Michele Mahone, Sharon Thompson, Carolyn Oldford, David McIntyre, Dynika St Omer, Raquel Dias, Martin D'Amours, Josephine Laurie, Leila MacBean, Nashwah Taha, Veronica Gale, Wayne Andrews, Heidi Virtanen, Judy Brandt, Heidi Hirsimaki, Mauricio Marin, Gail Klein, Heather Clark, Bernadette Rowe, Joel Ray, Julie Lee, Mark McLean, Siobhan Tobin, Anne-Marie Powell, Janine Malcolm, Paul J. Karanicolas, Claire Gougeon, Leanne De Souza, Elaine O'Shea, Cathy Robb, Marci Turner, Jill Newstead-Angel, Sharon Young, Joan Crane, Leslie Berndl, Simona Meier, Valérie-Ève Julien, Maureen Mattick, Lorraine L. Lipscombe, Simon Tian, Lisa Vizza, Karen Coles, Ken Lim, Razita Singh, Abhay Lodha, George Tomlinson, Shari Segal, Marie-Christine Dubé, Barbara Cleave, Colette Favreau, Howard Berger, Florence Weber, Shital Gandhi, Carol Fergusson, Anthony Armson, Sarah Kwong, Margaret Watson, Michele Strom, George I Fantus, Steve Chalifoux, Ilana Halperin, Anne E. Cook, J Johanna Sanchez, Jillian Coolen, Marnie Nerdal-Bussell, Cheryl Verhesen, Debbie Fong, Marie-Josee Bedard, Susan Hendon, Allison Sigmund, Sara Meltzer, Madalena Neculau, Renee Kludas, Annie Castonguay, Jennifer M. Yamamoto, Bekki Cavallaro, Rshmi Khurana, Effie Viguiliouk, Camille Lambert, Helen R. Murphy, Cora Fanning, Grace Lee, Robyn L. Houlden, Laurie Slater, Eileen K. Hutton, Lorraine Cauchi, Janet Slaunwhite, Prem Lata, Lois E. Donovan, Debbie McGuire, Carolyn Bergan, Aarthi Kamath, Louise Bastien, Sarah Capes, Kathryn Mangoff, Rohit Rajagopal, Anne Tremellen, David Miller, Sophie Perreault, Louise Rheaume, Sherri Pockett, Sophie Leblanc, Christyne Allen, Wenjun Nie, Amira El-Messidi, Edmond A. Ryan, Denice S Feig, Christine Orr, Vinolia ArthurHayward, H. David McIntyre, Ariane Godbout, Denice S. Feig, Jennifer Sloan, Heather Rylance, Simon Yu Tian, Hamish Russell, Sylvie Daigle, Suzanne Williams, Diane Donat, Krista Rideout, Vivian Zhou, Carol Joyce, Krystyna Szwiega, Allan Karovitch, Marie-Claude Bourbonniere, Helen Barrett, Amir Hanna, Tina Kader, Claudia Bishop, I. George Fantus, Ruth McManus, Stephanie Cooper, Jennifer Klinke, Bi Lan Wo, Keitha McMurray, Brenda Galway, S. John Weisnagel, Erin Keely, Jodie Nema, Joyce Mitchell, Hélène Long, Frances Maguire, Alice Cheng, Munira Sultana, Melin Peng, Jane Fox, Evelyne Rey, Francina Carr, Galina Smushkin, Tammy McNab, Maria Wolfs, Helen G. Liley, David Simmons

Publikováno v: The lancet. Diabetesendocrinology. 8(10)

Summary Background Although metformin is increasingly being used in women with type 2 diabetes during pregnancy, little data exist on the benefits and harms of metformin use on pregnancy outcomes in these women. We aimed to investigate the effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948529904de7be95ce75d903d1fc85b9
https://pubmed.ncbi.nlm.nih.gov/33065062

Beyond glycaemic control: A cross-over, double-blinded, 24-week intervention with liraglutide in type 1 diabetes

Autor: Marie-Christine Dubé, S. John Weisnagel, Martin D'Amours

Publikováno v: Diabetes, obesitymetabolism. 20(1)

Aims To investigate the effects of 24 weeks of treatment with liraglutide added to basal/bolus insulin on anthropometric and metabolic parameters in overweight participants with type 1 diabetes. Methods In a double-blinded cross-over fashion, 15 part

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcbb9a4a124e02ca7a9706921d18bb7
https://pubmed.ncbi.nlm.nih.gov/28722271

Blood pressure-independent effect of angiotensin AT1 receptor blockade on renal endothelin-1 production in hypertensive uremic rats

Autor: Marcel Lebel, Yannick Dumont, Martin D'Amours, Richard Larivière

Publikováno v: Journal of Hypertension. 19:1479-1487

OBJECTIVE We recently reported that treatment of uremic rats with reduced renal mass with the angiotensin II (Ang II) subtype 1 receptor (AT1) antagonist losartan reduces endothelin-1 (ET-1) levels in blood vessels and in glomeruli. Although this sug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef477cd9e2663c3949862792a0bef69
https://doi.org/10.1097/00004872-200108000-00017

Increased Immunoreactive Endothelin-1 Levels in Blood Vessels and Glomeruli of Rats with Reduced Renal Mass

Autor: John H. Grose, Martin D'Amours, Iris Kingma, Luc Caron, Marcel Lebel, Richard Larivière

Publikováno v: Kidney and Blood Pressure Research. 20:372-380

Elevated plasma and urinary endothelin-1 (ET-1) levels have been reported in patients with renal failure as well as in remnant kidney models of chronic renal failure. We investigated whether these changes are related to increased ET-1 production in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca8abdf7566ad9431d865433129958a
https://doi.org/10.1159/000174251

Effect of Liraglutide on Fat Distribution in Type 1 Diabetes

Autor: S. John Weisnagel, Marie-Christine Dubé, Martin D'Amours

Publikováno v: Canadian Journal of Diabetes. 40:S14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b74c09acafe5b24e7a7e19efbba2c8c1
https://doi.org/10.1016/j.jcjd.2016.08.042