Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Martin Crockard"'
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Molecular testing for familial hypercholesterolaemia-associated mutations in a UK-based cohort: development of an NGS-based method and comparison with multiplex polymerase chain reaction and oligonucleotide arrays
Autor: Mike Khan, Tracey L Watson, Ian A Cree, Dimitris K. Grammatopoulos, Sarojini Pandey, Martin Crockard, Mark J Latten, Nigel P. Dyer, Kate L Lloyd, Anne Reiman
Publikováno v: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 53:654-662
Background Detection of disease-associated mutations in patients with familial hypercholesterolaemia is crucial for early interventions to reduce risk of cardiovascular disease. Screening for these mutations represents a methodological challenge sinc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d8e50f9dfd70183ae0a6567be16ad2
https://doi.org/10.1177/0004563216629170
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3
Hedgehog pathway overexpression in pancreatic cancer is abrogated by new-generation taxoid SB-T-1216
Autor: J. E. Doherty, Beatrice Mohelnikova-Duchonova, Beatrice Mohelnikova Duchonova, Zdeněk Kala, Helena Murray, Veronika Brynychova, Jan Mazanec, Martin Oliverius, David J. Hughes, Eva Honsova, Pavel Soucek, Radmila Lemstrová, Iwao Ojima, Jan Hlavsa, Matej Kocik, Martin Crockard
Publikováno v: The Pharmacogenomics Journal. 17:452-460
The Hedgehog pathway is one of the major driver pathways in pancreatic ductal adenocarcinoma. This study investigated prognostic importance of Hedgehog signaling pathway in pancreatic cancer patients who underwent a radical resection. Tumors and adja
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aea94b9bf985ebbb74645321330374d
https://doi.org/10.1038/tpj.2016.55
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4
Criteria required for an acceptable point-of-care test for UTI detection: Obtaining consensus using the Delphi technique
Autor: Gerard Gormley, S. Pattison, Michael M. Tunney, Deirdre Gilpin, Nichola-Jane M. Weir, Carmel Hughes, Martin Crockard, Paddy Kearney, Bob Stafford
Publikováno v: PLoS ONE
Weir, N-J M, Pattison, S H, Kearney, P, Stafford, B, Gormley, G J, Crockard, M A, Gilpin, D F, Tunney, M M & Hughes, C M 2018, ' Criteria required for an acceptable point-of-care test for UTI detection: Obtaining consensus using the Delphi technique ', PLoS ONE, vol. 13, no. 6, e0198595 . https://doi.org/10.1371/journal.pone.0198595
PLoS ONE, Vol 13, Iss 6, p e0198595 (2018)
BackgroundUrinary Tract Infections (UTIs) are common bacterial infections, second only to respiratory tract infections and particularly prevalent within primary care. Conventional detection of UTIs is culture, however, return of results can take betw
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720e7a01354ebaa6b33c645365a983f4
http://europepmc.org/articles/PMC5991694
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7
Genetic diagnosis of familial hypercholesterolaemia using a rapid biochip array assay for 40 common LDLR, APOB and PCSK9 mutations
Autor: Helena Murray, Peter Fitzgerald, Rosalind Martin, Mark J Latten, Padraig Hart, Martin Crockard, Colin A. Graham, John Victor Lamont, Deborah Bailie
Publikováno v: Atherosclerosis. 254
Background and aims Familial hypercholesterolaemia (FH) leads to a lifelong increase in plasma LDL levels with subsequent increase in premature vascular disease. Early diagnosis and treatment is the key to effective management of this condition. This
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc52ede7b3a997df91ac58c0583219b6
https://pubmed.ncbi.nlm.nih.gov/27680772
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8
Diagnostic accuracy of heart-type fatty acid–binding protein for the early diagnosis of acute myocardial infarction
Autor: Elizabeth Curtin, S. Peter FitzGerald, Mary Jo Kurth, John Victor Lamont, R. Ivan McConnell, C. Geraldine McMahon, Martin Crockard, Peter Crean
Publikováno v: The American Journal of Emergency Medicine. 30:267-274
Objective The aim of this study was to evaluate the diagnostic efficacy of multiple tests—heart-type fatty acid–binding protein (H-FABP), cardiac troponin I (cTnI), creatine kinase-MB, and myoglobin—for the early detection of acute myocardial i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b75504a34e85d08e55a38b995640e2
https://doi.org/10.1016/j.ajem.2010.11.022
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