Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Martin Cente"'
Publikováno v:
Cells, Vol 12, Iss 9, p 1235 (2023)
Rickettsial infections of the central nervous system (CNS) are manifested by severe neurological symptoms and represent a serious life-threatening condition. Despite the considerable health danger, only a few studies have been conducted focusing on t
Externí odkaz:
https://doaj.org/article/f60ca842d6af474bb41e358ff1a9cfb5
Autor:
Branislav Kovacech, Lubica Fialova, Peter Filipcik, Rostislav Skrabana, Monika Zilkova, Natalia Paulenka-Ivanovova, Andrej Kovac, Denisa Palova, Gabriela Paulikova Rolkova, Katarina Tomkova, Natalia Turic Csokova, Karina Markova, Michaela Skrabanova, Kristina Sinska, Neha Basheer, Petra Majerova, Jozef Hanes, Vojtech Parrak, Michal Prcina, Ondrej Cehlar, Martin Cente, Juraj Piestansky, Michal Fresser, Michal Novak, Monika Slavikova, Kristina Borsova, Viktoria Cabanova, Bronislava Brejova, Tomas Vinař, Jozef Nosek, Boris Klempa, Ludek Eyer, Vaclav Hönig, Martin Palus, Daniel Ruzek, Tereza Vyhlidalova, Petra Strakova, Blanka Mrazkova, Dagmar Zudova, Gizela Koubkova, Vendula Novosadova, Jan Prochazka, Radislav Sedlacek, Norbert Zilka, Eva Kontsekova
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103818- (2022)
Summary: Background: The emergence of new SARS-CoV-2 variants of concern B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma) and B.1.617.2 (Delta) that harbor mutations in the viral S protein raised concern about activity of current vaccines and therapeutic
Externí odkaz:
https://doaj.org/article/d503988bb92a4f8ca2f39b041da95550
Autor:
Petra Majerova, Alena Michalicova, Martin Cente, Jozef Hanes, Jozef Vegh, Agnes Kittel, Nina Kosikova, Viera Cigankova, Sandra Mihaljevic, Santosh Jadhav, Andrej Kovac
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217216 (2019)
Tauopathies represent a heterogeneous group of neurodegenerative disorders characterized by abnormal deposition of the hyperphosphorylated microtubule-associated protein tau. Chronic neuroinflammation in tauopathies is driven by glial cells that pote
Externí odkaz:
https://doaj.org/article/55efaa1e07344466b30c669a16f2e0c5
Autor:
Martin Cente, Janka Perackova, Pavol Peracek, Marek Majdan, Igor Toth, Martin Mikulic, Jozef Hanes, Sara Porubska, Marian Spajdel, Barbora Kazickova, Igor Jurisica, Peter Filipcik
IMPORTANCEHead impacts resulting in traumatic brain injury (TBI) lead to elevation of phosphorylated tau protein in plasma, the biomarkers for patients with acute and chronic TBI. Dynamics of phosphorylated tau protein level (pTau) and ratio of pTau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca08ccfe612e93661626e0f18919556f
https://doi.org/10.1101/2022.10.13.22281039
https://doi.org/10.1101/2022.10.13.22281039
Autor:
Martin Cente, Janka Perackova, Pavol Peracek, Marek Majdan, Igor Toth, Martin Mikulic, Jozef Hanes, Sara Porubska, Marian Spajdel, Barbora Kazickova, Igor Jurisica, Peter Filipcik
Publikováno v:
JAMA Network Open. 6:e236101
ImportanceHead impacts resulting in traumatic brain injury (TBI) lead to the elevation of phosphorylated tau protein (p-tau181) in plasma. To our knowledge, this study is the first to investigate dynamics of p-tau181 levels and the ratio of p-tau181
Publikováno v:
General physiology and biophysics. 40:523-539
Discovering novel diagnostic biomarkers and signatures for traumatic brain injury (TBI) represents a major challenge in the brain trauma research. Detailed analysis of post-concussive molecular pathways based on experimental data could provide a new
Autor:
Marek Majdan, Igor Tóth, Janka Peráčková, Silvio Parničan, Peter Filipcik, Martin Cente, Patrik Barila, Pavol Peráček
Publikováno v:
General physiology and biophysics. 40:569-576
Traumatic brain injury in contact sports can lead to serious health consequences either immediately or later in the life of injured subjects. The objective of this study was to estimate the incidence of head impacts in the Under 18 (U18) and Under 20
Autor:
Martin, Cente, Tomas, Smolek, Stefan, Zorad, Lubica, Fialova, Natalia, Paulenka Ivanovova, Katarina, Krskova, Lucia, Balazova, Rostislav, Skrabana, Peter, Filipcik
Publikováno v:
General physiology and biophysics. 40:577-584
Neurodegeneration is associated with hypertension and disturbance in fat metabolism. The complex interaction of neurodegenerative processes with both metabolic changes and blood pressure is still not fully elucidated. Here we demonstrate that the exp
Autor:
Katarina Matyasova, Nikoleta Csicsatkova, Norbert Zilka, Santosh Jadhav, Tomas Smolek, Lucie Kawecka, Martin Cente, Veronika Mate, Veronika Brezovakova, Peter Szalay
Publikováno v:
General physiology and biophysics. 40:541-549
Spreading of tau pathology to anatomical distinct regions in Alzheimer's disease (AD) is associated with progression of the disease. Studies in recent decade have strived to understand the processes involved in this characteristic spread. We recently
Autor:
Lucia Balazova, Rostislav Skrabana, Peter Filipcik, Katarina Krskova, Tomas Smolek, Natalia Ivanovova, Lubica Fialova, Stefan Zorad, Martin Cente
Publikováno v:
Cellular and Molecular Neurobiology. 42:125-136
The close relationship between Alzheimer's disease (AD) and obesity was recognized many years ago. However, complete understanding of the pathological mechanisms underlying the interactions between degeneration of CNS and fat metabolism is still miss