Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Martin C. Whittle"'
Autor:
Christine A. Iacobuzio-Donahue, Sunil R. Hingorani, Steven D. Leach, Leslie Cope, Breanna M. Javier, Brian T. Herbst, Justin Poling, Zachary A. Kohutek, Alvin Makohon-Moore, Martin C. Whittle, Tyler Saunders, Anne Macgregor-Das, Yi Zhong
Col6A1 and Lcn2 promote the migration of PDA cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20dd748ce781a49a11aaf9743d9e265
https://doi.org/10.1158/1078-0432.22456503
https://doi.org/10.1158/1078-0432.22456503
Autor:
Norman E. Sharpless, Charles M. Perou, Gary L. Johnson, William C. Zamboni, Jian Jin, Austin J. Combest, Soren M. Johnson, James S. Duncan, Martin C. Whittle, Adam D. Pfefferle, Patrick M. Dillon, David B. Darr, Jerry E. Usary, Patrick J. Roberts
PDF file, 53K, MP1U Dosing Regimens.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06aab9f024e8516676b9d1a778432315
https://doi.org/10.1158/1078-0432.22455326.v1
https://doi.org/10.1158/1078-0432.22455326.v1
Autor:
Christine A. Iacobuzio-Donahue, Sunil R. Hingorani, Steven D. Leach, Leslie Cope, Breanna M. Javier, Brian T. Herbst, Justin Poling, Zachary A. Kohutek, Alvin Makohon-Moore, Martin C. Whittle, Tyler Saunders, Anne Macgregor-Das, Yi Zhong
KPC and KPTC Secretomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b897a48f2444f52027d50dcbce67b512
https://doi.org/10.1158/1078-0432.22456494.v1
https://doi.org/10.1158/1078-0432.22456494.v1
Autor:
Christine A. Iacobuzio-Donahue, Sunil R. Hingorani, Steven D. Leach, Leslie Cope, Breanna M. Javier, Brian T. Herbst, Justin Poling, Zachary A. Kohutek, Alvin Makohon-Moore, Martin C. Whittle, Tyler Saunders, Anne Macgregor-Das, Yi Zhong
Histologic features of liver metastases in KPTC, KPC, KTC and KC mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e499e60547670b6fe4ffd452386824
https://doi.org/10.1158/1078-0432.22456506.v1
https://doi.org/10.1158/1078-0432.22456506.v1
Autor:
Christine A. Iacobuzio-Donahue, Sunil R. Hingorani, Steven D. Leach, Leslie Cope, Breanna M. Javier, Brian T. Herbst, Justin Poling, Zachary A. Kohutek, Alvin Makohon-Moore, Martin C. Whittle, Tyler Saunders, Anne Macgregor-Das, Yi Zhong
Purpose: TP53 and the TGFβ pathway are major mediators of pancreatic cancer metastasis. The mechanisms by which they cause hematogenous metastasis have not been fully explored.Experimental Design: KPC (LSL-KRASG12D/+;LSL-Trp53R172H/+; Ptf1aCre/+) mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b040774e46cbef445bed4778a865831
https://doi.org/10.1158/1078-0432.c.6523332.v1
https://doi.org/10.1158/1078-0432.c.6523332.v1
Autor:
Christine A. Iacobuzio-Donahue, Sunil R. Hingorani, Steven D. Leach, Leslie Cope, Breanna M. Javier, Brian T. Herbst, Justin Poling, Zachary A. Kohutek, Alvin Makohon-Moore, Martin C. Whittle, Tyler Saunders, Anne Macgregor-Das, Yi Zhong
Patterns of Metastatic Spread by Genotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565df8f55a76383fcf8cbe0240351b12
https://doi.org/10.1158/1078-0432.22456500.v1
https://doi.org/10.1158/1078-0432.22456500.v1
Autor:
Norman E. Sharpless, Charles M. Perou, Gary L. Johnson, William C. Zamboni, Jian Jin, Austin J. Combest, Soren M. Johnson, James S. Duncan, Martin C. Whittle, Adam D. Pfefferle, Patrick M. Dillon, David B. Darr, Jerry E. Usary, Patrick J. Roberts
Purpose: Anticancer drug development is inefficient, but genetically engineered murine models (GEMM) and orthotopic, syngeneic transplants (OST) of cancer may offer advantages to in vitro and xenograft systems.Experimental Design: We assessed the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12662f1438dbf6c4e5e9ee67c13703ba
https://doi.org/10.1158/1078-0432.c.6522992
https://doi.org/10.1158/1078-0432.c.6522992
Autor:
Christine A. Iacobuzio-Donahue, Sunil R. Hingorani, Steven D. Leach, Leslie Cope, Breanna M. Javier, Brian T. Herbst, Justin Poling, Zachary A. Kohutek, Alvin Makohon-Moore, Martin C. Whittle, Tyler Saunders, Anne Macgregor-Das, Yi Zhong
Genotyping of Mice and Features of PanINs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996ccf47351b9beeced2c9e928e1da57
https://doi.org/10.1158/1078-0432.22456512.v1
https://doi.org/10.1158/1078-0432.22456512.v1
Autor:
Bo Tu, Heather Wright T. Wright, Christopher C. Dufort, Martin C. Whittle, Libing Feng, Shelley M. Thorsen, Sunil R. Hingorani
Publikováno v:
Cancer Research. 82:A056-A056
A defining characteristic of pancreatic ductal adenocarcinoma (PDA) is its robust desmoplastic reaction that promotes tumor progression and protects PDA from treatment. As a major component of the extreme microenvironment, hyaluronan (HA) is synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2ec26e5f80be0924bb72a747ee113ca
https://doi.org/10.1158/1538-7445.panca22-a056
https://doi.org/10.1158/1538-7445.panca22-a056
Autor:
Matthew J Cooper, Nathan J Cox, Eric I Zimmerman, Brian J Dewar, James S Duncan, Martin C Whittle, Thien A Nguyen, Lauren S Jones, Sreerupa Ghose Roy, David M Smalley, Pei Fen Kuan, Kristy L Richards, Richard I Christopherson, Jian Jin, Stephen V Frye, Gary L Johnson, Albert S Baldwin, Lee M Graves
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66755 (2013)
Protein kinases play key roles in oncogenic signaling and are a major focus in the development of targeted cancer therapies. Imatinib, a BCR-Abl tyrosine kinase inhibitor, is a successful front-line treatment for chronic myelogenous leukemia (CML). H
Externí odkaz:
https://doaj.org/article/5e341c4d37844eceabaaf81238a3ae18