Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Martin C. Heiss"'
Autor:
Simone Pelizzari, Martin C. Heiss, Monica L. Fernández-Quintero, Yousra El Ghaleb, Klaus R. Liedl, Petronel Tuluc, Marta Campiglio, Bernhard E. Flucher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Skeletal muscle contractions are initiated by action potentials, which are sensed by the voltage-gated calcium channel (CaV1.1) and are conformationally coupled to calcium release from intracellular stores. Notably, CaV1.1 contains four sepa
Externí odkaz:
https://doaj.org/article/4b3622b2fdfd47c48bbf270c78f4c6df
Autor:
Monica L. Fernández-Quintero, Katharina B. Kroell, Martin C. Heiss, Johannes R. Loeffler, Patrick K. Quoika, Franz Waibl, Alexander Bujotzek, Ekkehard Moessner, Guy Georges, Klaus R. Liedl
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Fab consist of a heavy and light chain and can be subdivided into a variable (VH and VL) and a constant region (CH1 and CL). The variable region contains the complementarity-determining region (CDR), which is formed by six hypervariable loops, shapin
Externí odkaz:
https://doaj.org/article/17bd5b59030048158efa6156e20c1d2f
Autor:
Monica L. Fernández-Quintero, Martin C. Heiss, Nancy D. Pomarici, Barbara A. Math, Klaus R. Liedl
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
In the past decade, the relevance of antibodies as therapeutics has increased substantially. Therefore, structural and functional characterization, in particular of the complementarity-determining regions (CDRs), is crucial to the design and engineer
Externí odkaz:
https://doaj.org/article/1a79298688a04a2b88d16168dab16c49
Autor:
Martin C. Heiss, Monica L. Fernandez-Quintero, Simone Pelizzari, Yousra El Ghaleb, Marta Campiglio, Petronel Tuluc, Klaus R. Liedl, Bernhard E. Flucher
Publikováno v:
Biophysical Journal. 122:106a-107a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d56077da9fad3628a04bd086d99d97a
https://doi.org/10.1016/j.bpj.2022.11.759
https://doi.org/10.1016/j.bpj.2022.11.759
Autor:
Simone Pelizzari, Monica L. Fernandez-Quintero, Marta Campiglio, Petronel Tuluc, Yousra El Ghaleb, Martin C. Heiss, Bernhard E. Flucher
Publikováno v:
Biophysical Journal. 122:376a-377a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e10b6785c2126ecceebcf7ef6bddba0
https://doi.org/10.1016/j.bpj.2022.11.2071
https://doi.org/10.1016/j.bpj.2022.11.2071
Autor:
Monica L. Fernández-Quintero, Simone Pelizzari, Yousra El Ghaleb, Martin C. Heiss, Klaus R. Liedl, Bernhard E. Flucher
Publikováno v:
Biophysical Journal. 122:106a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::070896804d37c29c16ce820508f80a70
https://doi.org/10.1016/j.bpj.2022.11.758
https://doi.org/10.1016/j.bpj.2022.11.758
Autor:
Simone Pelizzari, Yousra El Ghaleb, Martin C. Heiss, Monica L. Fernández-Quintero, Petronel Tuluc, Marta Campiglio, Bernhard E. Flucher
Publikováno v:
Biophysical Journal. 121:88a-89a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59998634b0f53f39fd63e3718bb9e46a
https://doi.org/10.1016/j.bpj.2021.11.2260
https://doi.org/10.1016/j.bpj.2021.11.2260
Publikováno v:
Protein Engineering, Design and Selection
Antibody engineering of non-human antibodies has focused on reducing immunogenicity by humanization, being a major limitation in developing monoclonal antibodies. We analyzed four series of antibody binding fragments (Fabs) and a variable fragment (F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0c808111de946b84d639e1f88f9826
https://doi.org/10.1093/protein/gzaa004
https://doi.org/10.1093/protein/gzaa004
Autor:
Martin C. Heiss, Monica L. Fernandez-Quintero, Yousra El Ghaleb, Simone Pelizzari, Petronel Tuluc, Marta Campiglio, Klaus R. Liedl, Bernhard E. Flucher
Publikováno v:
Biophysical Journal. 121:90a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a6d4d33e07b38bd5fc376c87c4d568a
https://doi.org/10.1016/j.bpj.2021.11.2268
https://doi.org/10.1016/j.bpj.2021.11.2268