Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Martin C. Abba"'
Autor:
Mariana Cooke, Gabriel Kreider-Letterman, Martin J. Baker, Suli Zhang, Neil T. Sullivan, Evgeniy Eruslanov, Martin C. Abba, Silvia M. Goicoechea, Rafael García-Mata, Marcelo G. Kazanietz
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109905- (2021)
Summary: Despite the undisputable role of the small GTPase Rac1 in the regulation of actin cytoskeleton reorganization, the Rac guanine-nucleotide exchange factors (Rac-GEFs) involved in Rac1-mediated motility and invasion in human lung adenocarcinom
Externí odkaz:
https://doaj.org/article/224c07e16fe044f2b5b738435738af84
Autor:
Martin C. Abba, María Laura Fabre, Jaeho Lee, Pradeep Tatineni, Hyunsuk Kil, C. Marcelo Aldaz
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The long-non-coding HOX transcript antisense intergenic RNA (HOTAIR) was identified as significantly upregulated in breast ductal carcinoma in situ (DCIS). The aim of this study was to characterize the phenotypic effects and signaling pathways modula
Externí odkaz:
https://doaj.org/article/5594fe79e39c4b5ba772736ca4a05dd7
Autor:
Soledad Iseas, Mariano Golubicki, Juan Robbio, Gonzalo Ruiz, Florencia Guerra, Javier Mariani, Ruben Salanova, Ana Cabanne, Martin Eleta, Joaquin V. Gonzalez, Jorge Basiletti, María Alejandra Picconi, Guillermo Masciangioli, Marcela Carballido, Enrique Roca, Guillermo Mendez, Mariana Coraglio, Martin C. Abba
Publikováno v:
Translational Oncology, Vol 14, Iss 6, Pp 101084- (2021)
Anal squamous cell carcinoma (ASCC) is a rare gastrointestinal malignancy associated with high-risk Human papillomavirus (HPV) infection. Despite improved outcomes in non-metastatic ASCC, definitive chemoradiotherapy constitutes the standard treatmen
Externí odkaz:
https://doaj.org/article/65161e8c619f4d85990bdd8aaec32720
Autor:
Tabish Hussain, Hyunsuk Kil, Bharathi Hattiangady, Jaeho Lee, Maheedhar Kodali, Bing Shuai, Sahithi Attaluri, Yoko Takata, Jianjun Shen, Martin C. Abba, Ashok K. Shetty, C. Marcelo Aldaz
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 163-176 (2019)
The association of WW domain-containing oxidoreductase WWOX gene loss of function with central nervous system (CNS) related pathologies is well documented. These include spinocerebellar ataxia, epilepsy and mental retardation (SCAR12, OMIM: 614322) a
Externí odkaz:
https://doaj.org/article/b2b23f03ce6f4a2397a5ee27171f943e
Publikováno v:
Stem Cells International, Vol 2020 (2020)
Mesenchymal stem/stromal cells (MSCs) exhibit multidifferentiation potential, paralleled with immunomodulatory and trophic properties that make them viable alternative tools for the treatment of degenerative disorders, allograft rejection, autoimmune
Externí odkaz:
https://doaj.org/article/732f0bf4f43242aca1c7a07eb40f24ff
Autor:
Rachana Garg, Jorge M. Blando, Carlos J. Perez, Martin C. Abba, Fernando Benavides, Marcelo G. Kazanietz
Publikováno v:
Cell Reports, Vol 19, Iss 2, Pp 375-388 (2017)
Summary: PKCε, an oncogenic member of the PKC family, is aberrantly overexpressed in epithelial cancers. To date, little is known about functional interactions of PKCε with other genetic alterations, as well as the effectors contributing to its tum
Externí odkaz:
https://doaj.org/article/4816a2556646420e8ca42d9414d70505
Autor:
María Candelaria Llorens, Fabiana Alejandra Rossi, Iris Alejandra García, Mariana Cooke, Martin C. Abba, Cynthia Lopez-Haber, Laura Barrio-Real, María Victoria Vaglienti, Mario Rossi, José Luis Bocco, Marcelo G. Kazanietz, Gastón Soria
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
ZEB1 is a master regulator of the Epithelial-to-Mesenchymal Transition (EMT) program. While extensive evidence confirmed the importance of ZEB1 as an EMT transcription factor that promotes tumor invasiveness and metastasis, little is known about its
Externí odkaz:
https://doaj.org/article/ea4079824ca24cf1999973aeca05bf3b
Autor:
Kevin M. McBride, Hyunsuk Kil, Yunxiang Mu, Joshua B. Plummer, Jaeho Lee, Maciej J. Zelazowski, Manu Sebastian, Martin C. Abba, C. Marcelo Aldaz
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
WWOX (WW domain containing oxidoreductase) expression loss is common in various cancers and characteristic of poor prognosis. Deletions, translocations, and loss of expression affecting the WWOX gene are a common feature of various B cell neoplasms s
Externí odkaz:
https://doaj.org/article/e5fe1f8308c34c35a6c5898c7b8a631f
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
It has become clear from multiple studies that WWOX (WW domain-containing oxidoreductase) operates as a “non-classical” tumor suppressor of significant relevance in cancer progression. Additionally, WWOX has been recognized for its role in a much
Externí odkaz:
https://doaj.org/article/7c389174fe834a4d9937718a223d2de6
Autor:
Martin C. Abba, Romina Canzoneri, Agustina Gurruchaga, Jaeho Lee, Pradeep Tatineni, Hyunsuk Kil, Ezequiel Lacunza, C. Marcelo Aldaz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7407 (2020)
Long intergenic non-protein coding RNA 885 (LINC00885) was identified as significantly upregulated in breast ductal carcinoma in situ (DCIS). The aim of this study was to characterize the phenotypic effects and signaling pathways modulated by LINC008
Externí odkaz:
https://doaj.org/article/173dff629d22479ebba42a9d98d74b08