Zobrazeno 1 - 10
of 707
pro vyhledávání: '"Martin C Michel"'
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Drug development faces the double challenge of increasing costs and increasing pressure on pricing. To avoid that lack of perceived commercial perspective will leave existing medical needs unmet, pharmaceutical companies and many other stakeholders a
Externí odkaz:
https://doaj.org/article/5d2de98168f8441e8d7e545493ad08fb
Publikováno v:
Frontiers in Medicine, Vol 3 (2016)
Aim: To explore the relationship between pathophysiological factors and premature lung ageing in a cohort of community-dwelling subjects in a health-screening setting. Methods: 16,107 pharmacy customers in Germany (5954 males, 10153 females; mean age
Externí odkaz:
https://doaj.org/article/9e762c4d2e344fd1aa61573065dbc8c7
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
The bioengineered tissue plasminogen activator tenecteplase is an important treatment modality of acute myocardial infarction recommended by international guidelines. Following introduction of originator tenecteplase (brand names Metalyse® and TNKas
Externí odkaz:
https://doaj.org/article/e839c7b3476b42c9b4edc2702e35818e
Autor:
Betul R. Erdogan, Zeynep E. Yesilyurt-Dirican, Irem Karaomerlioglu, Ayhanim Elif Muderrisoglu, Kadir Sevim, Martin C. Michel, Ebru Arioglu-Inan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10617 (2024)
Cardiovascular complications are the major cause of diabetes mellitus-related morbidity and mortality. Increased renin–angiotensin–aldosterone system activity and decreased β-adrenergic receptor (β-AR) responsiveness contribute to diabetic card
Externí odkaz:
https://doaj.org/article/c68254bc8c7548b69d2496740688c8f0
Publikováno v:
Frontiers in Pharmacology, Vol 3 (2012)
Racecadotril, via its active metabolite thiorphan, is an inhibitor of the enzyme neutral endopeptidase (NEP, EC 3.4.24.11), thereby increasing exposure to NEP including enkephalins and atrial natriuretic peptide. Upon oral administration racecadotril
Externí odkaz:
https://doaj.org/article/63fd908290dd4ef9b7b04f32d1663e45
Publikováno v:
Frontiers in Pharmacology, Vol 2 (2011)
The present study was primarily designed to explore various methodological aspects related to organ bath experiments evaluating human detrusor relaxation by the β-adrenoceptor agonist isoprenaline. Data are based upon a series of 30 consecutive pati
Externí odkaz:
https://doaj.org/article/44afd138d1bc42b0a43720ffc8af89e9
Autor:
Carla Sens-Albert, Sabrina Weisenburger, Beatrix C. König, Silas F. Melcher, Ulrike A. M. Scheyhing, Karin Rollet, Philippe Lluel, Egon Koch, Martin D. Lehner, Martin C. Michel
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Phytotherapeutics, particularly extracts from Sabal serrulata (saw palmetto) fruit or Urtica dioica (stinging nettle) root, are popular for the treatment of male lower urinary symptoms in many countries, but their mechanism of action is
Externí odkaz:
https://doaj.org/article/f65ae83f53f8473f891ec9ba2c6b715b
This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinica
Publikováno v:
Frontiers in Urology, Vol 3 (2023)
Externí odkaz:
https://doaj.org/article/0ee068923c144aac9efa932d5e6002cb
Autor:
A. Elif Müderrisoglu, Ayse A. Sakul, Sandra Murgas, Jean J. M. C. H. de la Rosette, Martin C. Michel
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Pelvic hypoperfusion caused by atherosclerosis has been proposed as a cause of lower urinary tract dysfunction including overactive bladder syndrome (OAB). Limited data indicate that OAB patients with concomitant diabetes or hypertensio
Externí odkaz:
https://doaj.org/article/ce18b18f2595418fa7fee7a0179f06cb