Phasevarions mediate random switching of gene expression in pathogenic Neisseria.

Autor: Yogitha N Srikhanta, Stefanie J Dowideit, Jennifer L Edwards, Megan L Falsetta, Hsing-Ju Wu, Odile B Harrison, Kate L Fox, Kate L Seib, Tina L Maguire, Andrew H-J Wang, Martin C Maiden, Sean M Grimmond, Michael A Apicella, Michael P Jennings

Publikováno v: PLoS Pathogens, Vol 5, Iss 4, p e1000400 (2009)

Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae, the random switching of the mod

Externí odkaz: https://doaj.org/article/08072cebc5074ae19882428ccdcc5b0b

Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents: evidence for herd protection from the UK MenACWY programme

Autor: Jeremy P. Carr, Jenny M. MacLennan, Emma Plested, Holly B. Bratcher, Odile B. Harrison, Parvinder K. Aley, James E. Bray, Susana Camara, Charlene M.C. Rodrigues, Kimberly Davis, Angela Bartolf, David Baxter, J. Claire Cameron, Richard Cunningham, Saul N. Faust, Katy Fidler, Rohit Gowda, Paul T. Heath, Stephen Hughes, Sujata Khajuria, David Orr, Mala Raman, Andrew Smith, David P.J. Turner, Elizabeth Whittaker, Christopher J. Williams, Christos S. Zipitis, Andrew J. Pollard, Jennifer Oliver, Begonia Morales-Aza, Aiswarya Lekshmi, Stephen A. Clark, Ray Borrow, Hannah Christensen, Caroline Trotter, Adam Finn, Martin C. Maiden, Matthew D. Snape, Keith A. Jolley, Karen Ford, Hannah Roberts, Karen Palmer, Debbie Suggitt, Nicola Pemberton, Samantha Ray, Mandy Wootton, Shamez N. Ladhani, Daniel Owens, Katrina Cathie, Simon Royal, Neil Oldfield, Roisin Ure, Jennifer Richards, Rebecca Ramsay, Samantha Thomson Hill, Kaltun Duale

Publikováno v: Carr, J P, MacLennan, J M, Plested, E, Bratcher, H B, Harrison, O B, Aley, P K, Oliver, J, Morales-Aza, B, Christensen, H & Maiden, M C & et, A 2022, ' Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents : evidence for herd protection from the UK MenACWY programme ', Clinical Microbiology and Infection, vol. 28, no. 12, pp. 1649.e1-1649.e8 . https://doi.org/10.1016/j.cmi.2022.07.004

Objective:Serogroup W and Y invasive meningococcal disease increased globally from 2000 onwards. Responding to a rapid increase in serogroup W clonal complex 11 (W:cc11) invasive meningococcal disease, the UK replaced an adolescent booster dose of me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bce77ca6a0e717154645cbc98f89339
https://researchonline.lshtm.ac.uk/id/eprint/4667094/1/Carr_etal_2022_Impact-of-meningococcal-acwy-conjugate.pdf

Partial Failure of Milk Pasteurization as a Risk for the Transmission of Campylobacter From Cattle to Humans

Autor: Anand M, Fernandes, Sooria, Balasegaram, Caroline, Willis, Helen M L, Wimalarathna, Martin C, Maiden, Noel D, McCarthy

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 61(6)

Cattle are the second most common source of human campylobacteriosis. However, routes to account for this scale of transmission have not been identified. In contrast to chicken, red meat is not heavily contaminated at point of sale. Although effectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3444e8a9bcc59a2b720b4702b27b17b6
https://pubmed.ncbi.nlm.nih.gov/26063713

Household transmission of Neisseria meningitidis in the African meningitis belt: a longitudinal cohort study

Autor: Kadidja Gamougam, Doumagoum Moto Dauglaz, Ibrahim Habiboulaye, Awa Traore, Sani Ousmane, Jean Pierre Gami, Thomas A. Clark, Leonard W. Mayer, Uma Onwuchekwa, Mahamadou Keita, Jacques Toralta, Aldiouma Diallo, Peter Wontuo, Eleanor R. Watkins, Arouna Woukeu, Martin C. J. Maiden, Boubou Tamboura, Daniel Chandramohan, Jean-Marc Collard, Kanny Diallo, Alemayehu Worku, Musa Hassan-King, Lawrence Yamuah, Ibrahim Dan Dano, Yenenesh K. Tekletsion, Abraham Hodgson, Isaac Osei, Rahamatou Moustapha Boukary, Bassira Issaka, Dorothea M. C. Hill, Lodoum Mbainadji, Abudulai Adams Forgor, Jules F. Gomis, Tesfaye Moti Demissie, Ahmed Bedru Omer, Galadima Gadzama, Xilian Bai, Assane Ndiaye, Abdoulaye Berthe, Stephen Laryea Quaye, Hubert Bassene, Akalifa Bugri, Maria Claudia Nascimento, Olivier Manigart, Jean-François Trape, Aliou Toure, Samba O. Sow, Omeiza Beida, Marietou Dieng, James M. Stuart, Nicole E. Basta, Thomas Irving, Odile B. Harrison, Sambo Zailani, Maxime Narbé, Babatunji A. Omotara, Brian Greenwood, Ray Borrow, Issoufa Rabe, Andromachi Karachaliou, Adama Coulibaly, Haimanot Guebre Xabher, Souleymane Doucoure, Cheikh Sokhna, Serge Alavo, Helen Findlow, Julia S. Bennett, Tsehaynesh Lema, Caroline Trotter, Abraham Aseffa, Shuaibu Yahya, Lisa S. Rebbetts, John W Williams, Jean-François Jusot, Oumer Ali, Mary Amodu, Nathan Naibei

Publikováno v: The Lancet global health
The Lancet global health, Elsevier, 2016, 4 (12), pp.e989-e995. ⟨10.1016/S2214-109X(16)30244-3⟩

Summary Background Information on transmission of meningococcal infection in the African meningitis belt is scarce. We aimed to describe transmission patterns of Neisseria meningitidis (meningococcus) in households in the African meningitis belt. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ad1ad9766cd5a2825bf1768b599cfe