Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Martin C Garnett"'
Autor:
Delyan P Ivanov, Terry L Parker, David A Walker, Cameron Alexander, Marianne B Ashford, Paul R Gellert, Martin C Garnett
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103817 (2014)
Three-dimensional cell culture has many advantages over monolayer cultures, and spheroids have been hailed as the best current representation of small avascular tumours in vitro. However their adoption in regular screening programs has been hindered
Externí odkaz:
https://doaj.org/article/226027e9245b4a4a9d0e97ed2e742059
Autor:
Sally Gittings, Jong Bong Lee, Alessandro Iachelini, Clive J. Roberts, Joanne Bennett, Joseph Ali, Pavel Gershkovich, Martin C. Garnett, Anne Cram
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 160:125-133
Drug release within the oral cavity can be of paramount importance for formulations that are designed for specific purposes such as taste-masking, faster onset of therapeutic action, localization of treatment or avoidance of first-pass metabolism. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81379b368712e4641aebfe0686d2fd79
https://doi.org/10.1016/j.ejpb.2021.01.017
https://doi.org/10.1016/j.ejpb.2021.01.017
Publikováno v:
Polymers, Vol 11, Iss 10, p 1561 (2019)
The enzymatically synthesized poly (glycerol adipate) (PGA) has demonstrated all the desirable key properties required from a performing biomaterial to be considered a versatile “polymeric-tool” in the broad field of drug delivery. The step-growt
Externí odkaz:
https://doaj.org/article/35ee0c3f02594f669724770e5e8faa8f
Autor:
Kanokporn Damrongrak, Kiattiphant Kloysawat, Somnuk Bunsupa, Krisada Sakchasri, Amaraporn Wongrakpanich, Vincenzo Taresco, Valentina Cuzzucoli Crucitti, Martin C. Garnett, Jiraphong Suksiriworapong
Publikováno v:
International journal of pharmaceutics. 618
The study demonstrated the fabrication of new poly(glycerol adipate) (PGA) nanoparticles decorated with folic acid (FOL-PGA) and triphenylphosphonium (TPP-PGA) and the potential on the delivery of acetogenin-enriched Annona muricata Linn leaf extract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504b65b2cbcffc21b85df2ad1202e297
https://pubmed.ncbi.nlm.nih.gov/35259439
https://pubmed.ncbi.nlm.nih.gov/35259439
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08125-(2021)
Heliyon
Heliyon
Plant derived cysteine proteinases (CPs) have long been known to possess anthelmintic properties but have attracted renewed attention recently because of the acute need to discover novel methods for controlling helminth infections as a result of incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0812c618a1d51469a5b85bf62aeb7e3
http://www.sciencedirect.com/science/article/pii/S2405844021022283
http://www.sciencedirect.com/science/article/pii/S2405844021022283
Autor:
Lucie H. Clapp, Barry Ager, Mark McAllister, Vincenzo Taresco, Martin C. Garnett, Sadie M.E. Swainson, Amanda K. Pearce, Cynthia Bosquillon
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 142:377-386
Poly(glycerol adipate) (PGA) is a biodegradable, biocompatible, polymer with a great deal of potential in the field of drug delivery. Active drug molecules can be conjugated to the polymer backbone or encapsulated in self-assembled nanoparticles for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebca8de790848a57bb06e6b6faf3b43d
https://doi.org/10.1016/j.ejpb.2019.07.015
https://doi.org/10.1016/j.ejpb.2019.07.015
Autor:
Anna M. Grabowska, Martin C. Garnett, Aleksandra Tchoryk, Marianne Ashford, Richard H. Argent, Snow Stolnik, Vincenzo Taresco, Paul Gellert
Publikováno v:
Bioconjugate Chemistry. 30:1371-1384
Animal models are effective for assessing tumor localization of nanosystems but difficult to use for studying penetration beyond the vasculature. Here, we have used well-characterized HCT116 colorectal cancer spheroids to study the effect of nanopart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9a2089a6bde1a8124a17ef547d0b65
https://doi.org/10.1021/acs.bioconjchem.9b00136
https://doi.org/10.1021/acs.bioconjchem.9b00136
Autor:
Martin C. Garnett, Sadie M.E. Swainson, Vincenzo Taresco, David Walker, Rashidat K. Animasawun, Jiraphong Suksiriworapong
Publikováno v:
Molecular pharmaceutics. 17(6)
Key challenges hindering the clinical translation of the use of nanoparticles (NP) for delivery of drugs to tumors are inadequate drug loading and premature drug release. This study focused on understanding the conditions required to produce nanopart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84191af95faa3d117b77ab96ad0bdfa
https://pubmed.ncbi.nlm.nih.gov/32348676
https://pubmed.ncbi.nlm.nih.gov/32348676
Autor:
Vincenzo Taresco, Ioanna Danai Styliari, Andrew Lewis Theophilus, Charles A. Laughton, Cameron Alexander, Martin C. Garnett
Publikováno v:
RSC advances. 10(33)
The formulation of drug compounds into nanoparticles has many potential advantages in enhancing bioavailability and improving therapeutic efficacy. However, few drug molecules will assemble into stable, well-defined nanoparticulate structures. Amphip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c00085dd7b1d26874bdec994046707
https://pubmed.ncbi.nlm.nih.gov/35515456
https://pubmed.ncbi.nlm.nih.gov/35515456
Publikováno v:
Journal of Drug Delivery Science and Technology. 46:354-364
Nucleoside analogues are active therapeutic agents for different types of diseases e.g. Cancer and virus infections. However, they are associated with several side effects due to off-target accumulation. Particulate delivery systems such as nanoparti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a4ea6fa500acc195bc3695ca475c0a8
https://doi.org/10.1016/j.jddst.2018.05.027
https://doi.org/10.1016/j.jddst.2018.05.027