Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Martin Bruun Madsen"'
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Objectives Application of hyperbaric oxygen (HBO2) treatment in the multidisciplinary setting of necrotising soft-tissue infection (NSTI) is debated as a considerable number of studies are of low quality with marked prognostication bias due to inadeq
Externí odkaz:
https://doaj.org/article/24bce2a0ecaa40699977a084b3ef59cc
Publikováno v:
Journal of Innate Immunity, Pp 1-11 (2021)
The hyperinflammatory burden is immense in necrotizing soft-tissue infection (NSTI). The complement system is a key during the innate immune response and may be a promising target to reduce the inflammatory response, potentially improving the clinica
Externí odkaz:
https://doaj.org/article/c6c6a22908c849f5bb910249a1d54395
Autor:
Morten Hedetoft, Marco Bo Hansen, Martin Bruun Madsen, Julia Sidenius Johansen, Ole Hyldegaard
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Necrotizing soft-tissue infection (NSTI) is a severe and fast-progressing bacterial infection. Prognostic biomarkers may provide valuable information in treatment guidance and decision-making, but none have provided sufficient rob
Externí odkaz:
https://doaj.org/article/6be3608ddaf4482eb802f127a3a402e8
Autor:
Gustav Torisson, MD, PhD, Martin Bruun Madsen, MD, PhD, Agnes Schmidt Davidsen, MD, Anders Perner, MD, PhD, Jeffrey Lipman, MD, Joel Dulhunty, PhD, Fredrik Sjövall, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 5, p e0383 (2021)
Objectives:. To explore the association between antibiotic combination therapy and in-hospital mortality in patients with septic shock in two tertiary ICUs in different countries. Design:. Retrospective observational study. Setting:. ICUs of two tert
Externí odkaz:
https://doaj.org/article/045fb87614894c2eb63e0454a8ebf1e9
Autor:
Robert Thänert, Andreas Itzek, Jörn Hoßmann, Domenica Hamisch, Martin Bruun Madsen, Ole Hyldegaard, Steinar Skrede, Trond Bruun, Anna Norrby-Teglund, INFECT study group, Eva Medina, Dietmar H. Pieper
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Necrotizing soft tissue infections (NSTIs) are caused by a single pathogen such as Streptococcus pyogenes or by multiple bacterial species. Here, the authors integrate microbial community profiling with host and pathogen transcriptional analysis in p
Externí odkaz:
https://doaj.org/article/a71db1a3f33741e88b0fff82cb740d6b
Publikováno v:
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Background The pathophysiological understanding of the inflammatory response in necrotizing soft‐tissue infection (NSTI) and its impact on clinical progression and outcomes are not resolved. Hyperbaric oxygen (HBO2) treatment serves as an
Externí odkaz:
https://doaj.org/article/1a453dde7e7f4b6c86ca59ceec906a46
Publikováno v:
BMJ Open, Vol 10, Iss 10 (2020)
Objective To assess the incidence, comorbidities, treatment modalities and mortality in patients with necrotising soft-tissue infections (NSTIs) in Denmark.Design Nationwide population-based registry study.Setting Denmark.Participants Danish resident
Externí odkaz:
https://doaj.org/article/acfbcd46f5734196b548753279e91d34
Autor:
Markus Korsholm Kristensen, Marco Bo Hansen, Martin Bruun Madsen, Cecilie Bo Hansen, Katrine Pilely, Ole Hyldegaard, Peter Garred
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Aim: We assessed whether different complement factors and complement activation products were associated with poor outcome in patients with necrotizing soft-tissue infection (NSTI).Methods: We conducted a prospective, observational study in an intens
Externí odkaz:
https://doaj.org/article/22b7fbeabbfc452584e309b2744b001f
Autor:
Johannes Westman, Bhavya Chakrakodi, Johanna Snäll, Matthias Mörgelin, Martin Bruun Madsen, Ole Hyldegaard, Ariane Neumann, Inga-Maria Frick, Anna Norrby-Teglund, Lars Björck, Heiko Herwald
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Innate immunity relies on an effective recognition of the pathogenic microorganism as well as on endogenous danger signals. While bacteria in concert with their secreted virulence factors can cause a number of inflammatory reactions, danger signals r
Externí odkaz:
https://doaj.org/article/a3bd1c01143c4bdf858a00c49c66daec
Autor:
Maj‐Brit Nørregaard Kjær, Martin Bruun Madsen, Nick Meier, Anders Granholm, Morten Hylander Møller, Ingrid Egerod, Anders Perner
Publikováno v:
Acta Anaesthesiologica Scandinavica.