Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Martin Breitkreuz"'
Autor:
Martina Krüger, Sebastian Kötter, Alexander Dietl, Andreas Unger, Alexander Nickel, Belal A. Mohamed, Lars I. Leichert, Christoph Maack, Christine M Loescher, Martin Breitkreuz, Andreas J. Schmidt, Yong Li, Karl Toischer, Nazha Hamdani, Wolfgang A. Linke, Joachim P. Schmitt, Marcus Krüger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Titin oxidation alters titin stiffness, which greatly contributes to overall myocardial stiffness. This stiffness is frequently increased in heart disease, such as diastolic heart failure. We have quantified the degree of oxidative titin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0e48180cfb10b0b82478e2218a4128
https://doi.org/10.1073/pnas.2004900117
https://doi.org/10.1073/pnas.2004900117
Autor:
Nazha Hamdani, Martin Breitkreuz
Publikováno v:
Biophysical Reviews. 7:321-341
Redox/cysteine modification of proteins that regulate calcium cycling can affect contraction in striated muscles. Understanding the nature of these modifications would present the possibility of enhancing cardiac function through reversible cysteine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fda0a1ba7934e6ccb48e67ebd801d44
https://doi.org/10.1007/s12551-015-0175-5
https://doi.org/10.1007/s12551-015-0175-5
Autor:
Jorge Alegre-Cebollada, Julio M. Fernandez, Martin Breitkreuz, Nazha Hamdani, Lars I. Leichert, Wolfgang A. Linke
Publikováno v:
Biophysical Journal. 108:444a
Background: The elasticity of titin is regulated through several mechanisms, including isoform switching and phosphorylation of unique spring elements (N2-Bus, PEVK). However, the titin springs consist mainly of immunoglobulin-like (Ig) domains, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5f4b4ccc8c8743c233e8527e40546b
https://doi.org/10.1016/j.bpj.2014.11.2427
https://doi.org/10.1016/j.bpj.2014.11.2427