Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Martin Boland"'
Publikováno v:
Journal of Applied Pharmaceutical Science. :177-183
Publikováno v:
Drug and Alcohol Review. 35:206-211
Introduction and Aims Anecdotes of nicotine replacement therapy patch misuse associated with the introduction of smoke-free prisons have been reported by media internationally, including Canada in 2006, New Zealand in 2011 and Australia in 2014. This
Autor:
Amrita Sran, Rosemary L. Sparrow, Esther Bandala-Sanchez, Kasey Sze-Kei Chan, Diana Mittag, Olivier Huet, William Xu, Martin Boland
Publikováno v:
Transfusion. 55:2197-2206
BACKGROUND Biochemical changes induced in red blood cells (RBCs) during storage may impair their function upon transfusion. Transfusion-associated stresses may further amplify storage lesion effects including increased phosphatidylserine (PS) exposur
Autor:
Simon C. Drew, Cathryn L. Haigh, Anton P. Le Brun, Michael James, Martin Boland, Steven J. Collins
Publikováno v:
Biophysical Journal. 107:2313-2324
The prion protein (PrP), widely recognized to misfold into the causative agent of the transmissible spongiform encephalopathies, has previously been shown to bind to lipid membranes with binding influenced by both membrane composition and pH. Aside f
Publikováno v:
The British journal of educational psychology. 87(1)
Background and aims Lecturers often present entertaining videos, or organize a variety of amusing demonstrations, to foster student engagement or to encourage critical analysis. Magic tricks, in particular, have been shown to activate neural circuits
Autor:
Andrew F. Hill, Martin Boland, John A. Karas, Denis B. Scanlon, Vanessa A Johanssen, Kevin J. Barnham, Steven J. Collins, Cathryn L. Haigh
Publikováno v:
International Journal of Peptide Research and Therapeutics. 18:21-29
Misfolded conformers of the prion protein are aetiologically implicated in neurodegenerative conditions termed prion diseases (also known as transmissible spongiform encephalopathies). Two constitutively expressed N-terminal peptides corresponding to
Autor:
Andrew F. Hill, Deborah J. Tew, Frances Separovic, Martin Boland, Kevin J. Barnham, Steven J. Collins, Cathryn L. Haigh, Michael James, Claire R. Hatty, Colin L. Masters
Publikováno v:
Journal of Biological Chemistry. 285:32282-32292
Although the N terminus of the prion protein (PrP(C)) has been shown to directly associate with lipid membranes, the precise determinants, biophysical basis, and functional implications of such binding, particularly in relation to endogenously occurr
Autor:
Victoria A. Lawson, Cathryn L. Haigh, Colin L. Masters, Kevin J. Barnham, Steven J. Collins, Simon C. Drew, Martin Boland
Publikováno v:
Journal of Cell Science. 122:1518-1528
Beta-cleavage of the neurodegenerative disease-associated prion protein (PrP) protects cells from death induced by oxidative insults. The beta-cleavage event produces two fragments, designated N2 and C2. We investigated the role of the N2 fragment (r
Autor:
David A. Middleton, Martin Boland
Publikováno v:
Phys. Chem. Chem. Phys.. 10:178-185
Methods for determining how a drug interacts with cellular membranes at the molecular level can give valuable insight into the mode of action of the drug and its absorption, distribution and metabolism profile. A procedure is described here to determ
Autor:
John H. Bowie, Frances Separovic, Tara L. Pukala, Lucia Kuhn-Nentwig, Martin Boland, John D. Gehman
Publikováno v:
Biochemistry. 46:3576-3585
The solution structure of cupiennin 1a, a 35 residue, basic antibacterial peptide isolated from the venom of the spider Cupiennius salei, has been determined by nuclear magnetic resonance (NMR) spectroscopy. The peptide was found to adopt a helix−h