Výsledky vyhledávání - "Martin Bernheiden"

The novel HLA-DQB1*06 null allele, HLA-DQB1*06:423N, identified in a volunteer blood donor

Autor: Evelyn Loeser, Michael Hallensleben, Martin Bernheiden, Mirzokhid Rakhmanov, Florian Emmerich

Publikováno v: HLAREFERENCES. 100(2)

A single nucleotide exchange in exon 2 at position 370 (C -T) generates a preterminal STOP encoding a C-terminally truncated protein.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66af252a72c45a6b580ee4e29adaa84c
https://pubmed.ncbi.nlm.nih.gov/35439352

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Implications for a general role of LPS-binding proteins (CD14, LBP) in combating bacterial infections

Autor: Felix Stelter, René Menzel, Xiaolong Fan, Hans-Peter Müller, Robert Smail Jack, Martin Bernheiden, U. Grunwald, Christine Schütt

Publikováno v: Journal of Endotoxin Research. 5:75-80

An invading pathogen must be held in check by the innate immune system until a specific immune response can be mounted. In the case of Gram-negative bacteria, the principal stimulator is LPS, a component of the outer membrane of the bacteria. In vitr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efd7bef207d0c70d8ed632a57c4f75d2
https://doi.org/10.1177/09680519990050010601

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Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection

Autor: Monika Ehlers, Renate Mentel, Christine Schütt, Martin Bernheiden, Albert Weber, Felix Stelter, Birgit Fürll, Marina A. Freudenberg, Robert Smail Jack, Gerhard Kirsch, Gerd Schmitz, Xiaolong Fan, Gabriele M. Rune

Publikováno v: Nature. 389:742-745

An invading pathogen must be held in check by the innate immune system until a specific immune response can be mounted. In the case of Gram-negative bacteria, the principal stimulator of the innate immune system is lipopolysaccharide (LPS), a compone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e5ddef2f227783b76890bc0a8fadf5
https://doi.org/10.1038/39622

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Mutation of Amino Acids 39-44 of Human CD14 Abrogates Binding of Lipopolysaccharide and Escherichia coli

Autor: Sabine Witt, Martin Pfister, Robert Smail Jack, Martin Bernheiden, René Menzel, Felix Stelter, Christine Schütt, Xiaolong Fan

Publikováno v: European Journal of Biochemistry. 243:100-109

As a key receptor for lipopolysaccharide (LPS) on the surface of monocytes and macrophages, the CD14 molecule is primarily involved in non-specific host defense mechanisms against gram-negative bacteria. To delineate the structural basis of LPS bindi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e6c0e3ab3d5c865be5c092c8a5e72d
https://doi.org/10.1111/j.1432-1033.1997.00100.x

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LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection

Autor: Jan-Michael Heinrich, Felix Stelter, Martin Bernheiden, Mason W. Freeman, Robert Smail Jack, Gabriela Minigo, Christine Schütt, Douglas T. Golenbock

Publikováno v: Charles Darwin University

In mice, defense against an intraperitoneal Salmonella infection depends on a vigorous innate immune response. Mutations which lead to an inadequate early response to the pathogen thus identify genes involved in innate immunity. The best studied host

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dced026a20f5f3740f3338505ffb38d4
https://pubmed.ncbi.nlm.nih.gov/11753215

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