Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Martin Berke"'
Autor:
Tosson Elalaily, Martin Berke, Ilari Lilja, Alexander Savin, Gergő Fülöp, Lőrinc Kupás, Thomas Kanne, Jesper Nygård, Péter Makk, Pertti Hakonen, Szabolcs Csonka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract The observation of the gate-controlled supercurrent (GCS) effect in superconducting nanostructures increased the hopes for realizing a superconducting equivalent of semiconductor field-effect transistors. However, recent works attribute this
Externí odkaz:
https://doaj.org/article/007d26b3ecd8418a85092d55424e8911
Autor:
Shishan Wang, Marie-Laure Fogeron, Maarten Schledorn, Marie Dujardin, Susanne Penzel, Dara Burdette, Jan Martin Berke, Michael Nassal, Lauriane Lecoq, Beat H. Meier, Anja Böckmann
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Modulation of capsid assembly by small molecules has become a central concept in the fight against viral infection. Proper capsid assembly is crucial to form the high molecular weight structures that protect the viral genome and that, often in concer
Externí odkaz:
https://doaj.org/article/f3ba5dd1450b4b619e4a96f9091e6647
Autor:
Olivér Kürtössy, Péter Makk, Kenji Watanabe, Thomas Kanne, István Endre Lukács, Gergő Fülöp, Takashi Taniguchi, Tosson Elalaily, Martin Berke, Szabolcs Csonka, Zoltán Scherübl, Jesper Nygård
Publikováno v:
Nano Letters
Nano Letters, 2021, 21 (22), pp.9684-9690. ⟨10.1021/acs.nanolett.1c03493⟩
Elalaily, T, Kurtossy, O, Scherubl, Z, Berke, M, Fulop, G, Lukacs, I E, Kanne, T, Nygard, J, Watanabe, K, Taniguchi, T, Makk, P & Csonka, S 2021, ' Gate-Controlled Supercurrent in Epitaxial Al/InAs Nanowires ', Nano Letters, vol. 21, no. 22, pp. 9684-9690 . https://doi.org/10.1021/acs.nanolett.1c03493
Nano Letters, 2021, 21 (22), pp.9684-9690. ⟨10.1021/acs.nanolett.1c03493⟩
Elalaily, T, Kurtossy, O, Scherubl, Z, Berke, M, Fulop, G, Lukacs, I E, Kanne, T, Nygard, J, Watanabe, K, Taniguchi, T, Makk, P & Csonka, S 2021, ' Gate-Controlled Supercurrent in Epitaxial Al/InAs Nanowires ', Nano Letters, vol. 21, no. 22, pp. 9684-9690 . https://doi.org/10.1021/acs.nanolett.1c03493
Gate-controlled supercurrent (GCS) in superconducting nanobridges has recently attracted attention as a means to create superconducting switches. Despite the clear advantages for applications, the microscopic mechanism of this effect is still under d
Autor:
Lauriane Lecoq, Louis Brigandat, Rebecca Huber, Marie-Laure Fogeron, Shishan Wang, Marie Dujardin, Mathilde Briday, Thomas Wiegand, Morgane Callon, Alexander Malär, David Durantel, Dara Burdette, Jan Martin Berke, Beat H. Meier, Michael Nassal, Anja Böckmann
Publikováno v:
Nature Communications, 14 (1)
Hepatitis B virus (HBV) capsid assembly modulators (CAMs) represent a recent class of anti-HBV antivirals. CAMs disturb proper nucleocapsid assembly, by inducing formation of either aberrant assemblies (CAM-A) or of apparently normal but genome-less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbd116831a9401bf67b6009921d9fca
https://doi.org/10.1101/2022.09.14.507909
https://doi.org/10.1101/2022.09.14.507909
Autor:
Jean-Marc Neefs, Pascale Dehertogh, Oliver Lenz, Jan Martin Berke, Karen Vergauwen, Ying Tan, Gengyan Wang, Thierry Verbinnen, Edgar Jacoby
Publikováno v:
Journal of Antimicrobial Chemotherapy. 75:2526-2534
Objectives To characterize antiviral activity of the capsid assembly modulator (CAM-N) JNJ-56136379 against HBV genotypes and variants carrying amino acid substitutions in the core protein. Methods Anti-HBV activity of JNJ-56136379 was investigated a
Autor:
Jan Martin Berke, Loeckie de Zwart, Willem Talloen, Maarten van den Boer, Jan Snoeys, Joris Vandenbossche, Jeysen Yogaratnam, W. Jessner, Jeike Biewenga
Publikováno v:
Advances in Therapy. 36:2450-2462
Hepatitis B viral capsid assembly is an attractive target for new antiviral treatments. JNJ-56136379 (JNJ-6379) is a potent capsid assembly modulator in vitro with a dual mode of action. In Part 1 of this first-in-human study in healthy adults, the p
Autor:
Pierre Jean-Marie Bernard Raboisson, Jan Martin Berke, Wendy Mostmans, Karen Vergauwen, Pascale Dehertogh, Frederik Pauwels, Koen Vandyck
Publikováno v:
Antimicrob Agents Chemother
Capsid assembly is a critical step in the hepatitis B virus (HBV) life cycle, mediated by the core protein. Core is a potential target for new antiviral therapies, the capsid assembly modulators (CAMs). JNJ-56136379 (JNJ-6379) is a novel and potent C
Autor:
Moana Hodari, David Blue, Jan Martin Berke, Joris Vandenbossche, Sandra De Meyer, Jeysen Yogaratnam, Thierry Verbinnen, Oliver Lenz, Umesh Shukla, Willem Talloen
Publikováno v:
Journal of viral hepatitisREFERENCES. 27(11)
Four weeks of once-daily oral JNJ-56136379 (JNJ-6379; 25, 75, 150 or 250 mg), a class-N capsid assembly modulator (CAM-N), was well tolerated with potent antiviral activity in treatment-naive, chronic hepatitis B e antigen-positive and hepatitis B e
Autor:
Danielle Peeters, Sarah Sauviller, Emmanuel Gustin, Peter Vermeulen, Jan Martin Berke, Dirk Wuyts, Frederik Pauwels, Koen Vandyck, Steffen Jaensch, Karen Vergauwen
Publikováno v:
Journal of Virological Methods. 293:114150
Hepatitis B Virus (HBV) core protein has multiple functions in the viral life cycle and is an attractive target for new anti-viral therapies. Capsid assembly modulators (CAMs) target the core protein and induce the formation of either morphologically
Autor:
Leen Vijgen, Lotke Tambuyzer, Bart Stoops, Sophie Lachau-Durand, Abdellah Tahri, Laurent Leclercq, Tse-I Lin, Jan Snoeys, Kenny Simmen, Jan Martin Berke, Tim H. M. Jonckers, Pierre Jean-Marie Bernard Raboisson
Publikováno v:
Journal of Medicinal Chemistry. 59:5790-5798
JNJ-54257099 (9) is a novel cyclic phosphate ester derivative that belongs to the class of 2′-deoxy-2′-spirooxetane uridine nucleotide prodrugs which are known as inhibitors of the HCV NS5B RNA-dependent RNA polymerase (RdRp). In the Huh-7 HCV ge