Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Martin Bens"'
Autor:
Tsima Abou Kors, Matthias Meier, Lena Mühlenbruch, Annika C. Betzler, Franziska Oliveri, Martin Bens, Jaya Thomas, Johann M. Kraus, Johannes Doescher, Adrian von Witzleben, Linda Hofmann, Jasmin Ezic, Diana Huber, Julian Benckendorff, Thomas F. E. Barth, Jens Greve, Patrick J. Schuler, Cornelia Brunner, Jonathan M. Blackburn, Thomas K. Hoffmann, Christian Ottensmeier, Hans A. Kestler, Hans-Georg Rammensee, Juliane S. Walz, Simon Laban
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe human leukocyte antigen complex (HLA) is essential for inducing specific immune responses to cancer by presenting tumor-associated peptides (TAP) to T cells. Overexpressed tumor associated antigens, mainly cancer-testis antigens (CTA)
Externí odkaz:
https://doaj.org/article/395296b0c62b42a7af04bb14da175331
Autor:
Aishwarya Iyer-Bierhoff, Martin Wieczorek, Sina Marielle Peter, Dima Ward, Martin Bens, Sabine Vettorazzi, Karl-Heinz Guehrs, Jan P. Tuckermann, Thorsten Heinzel
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108943- (2024)
Summary: Glucocorticoid (GC) signaling is essential for mounting a stress response, however, chronic stress or prolonged GC therapy downregulates the GC receptor (GR), leading to GC resistance. Regulatory mechanisms that refine this equilibrium are n
Externí odkaz:
https://doaj.org/article/cf90c7c5d2ad4e608db75592fcbbf55b
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
In comparison to bulk sequencing or single cell sequencing, spatial transcriptomics preserves the spatial information in tissue slices and can even be mapped to immunofluorescent stainings, allowing translation of gene expression information into the
Externí odkaz:
https://doaj.org/article/395f6758eb2a4ccb846aa023f1755585
Autor:
Arne Sahm, Pedro Almaida-Pagán, Martin Bens, Mirko Mutalipassi, Alejandro Lucas-Sánchez, Jorge de Costa Ruiz, Matthias Görlach, Alessandro Cellerino
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Standard evolutionary theories of aging postulate that reduced extrinsic mortality leads to evolution of longevity. Clownfishes of the genus Amphiprion live in a symbiotic relationship with sea anemones that provide protection fro
Externí odkaz:
https://doaj.org/article/b5d77bba784e4384afc9f1d57f6ceb6d
Autor:
Arne Sahm, Matthias Platzer, Philipp Koch, Yoshiyuki Henning, Martin Bens, Marco Groth, Hynek Burda, Sabine Begall, Saskia Ting, Moritz Goetz, Paul Van Daele, Magdalena Staniszewska, Jasmin Mona Klose, Pedro Fragoso Costa, Steve Hoffmann, Karol Szafranski, Philip Dammann
Publikováno v:
eLife, Vol 10 (2021)
Sexual activity and/or reproduction are associated with a doubling of life expectancy in the long-lived rodent genus Fukomys. To investigate the molecular mechanisms underlying this phenomenon, we analyzed 636 RNA-seq samples across 15 tissues. This
Externí odkaz:
https://doaj.org/article/7604cc028b8242158c4940e90b47e895
Autor:
Ivonne Heinze, Martin Bens, Enrico Calzia, Susanne Holtze, Oleksandr Dakhovnik, Arne Sahm, Joanna M. Kirkpatrick, Karol Szafranski, Natalie Romanov, Sai Nagender Sama, Kerstin Holzer, Stephan Singer, Maria Ermolaeva, Matthias Platzer, Thomas Hildebrandt, Alessandro Ori
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-18 (2018)
Abstract Background Mammals display a wide range of variation in their lifespan. Investigating the molecular networks that distinguish long- from short-lived species has proven useful to identify determinants of longevity. Here, we compared the liver
Externí odkaz:
https://doaj.org/article/7d3091f112564f8b9a82f9ad024e5abe
Autor:
Martin Bens, Karol Szafranski, Susanne Holtze, Arne Sahm, Marco Groth, Hans A. Kestler, Thomas B. Hildebrandt, Matthias Platzer
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Naked mole-rats (NMRs) are eusocially organized in colonies. Although breeders carry the additional metabolic load of reproduction, they are extremely long-lived and remain fertile throughout their lifespan. This phenomenon contra
Externí odkaz:
https://doaj.org/article/4f7552ae407d4d5792b9d2629f6fa6e2
Autor:
Arne Sahm, Martin Bens, Karol Szafranski, Susanne Holtze, Marco Groth, Matthias Görlach, Cornelis Calkhoven, Christine Müller, Matthias Schwab, Johann Kraus, Hans A Kestler, Alessandro Cellerino, Hynek Burda, Thomas Hildebrandt, Philip Dammann, Matthias Platzer
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007272 (2018)
The genetics of lifespan determination is poorly understood. Most research has been done on short-lived animals and it is unclear if these insights can be transferred to long-lived mammals like humans. Some African mole-rats (Bathyergidae) have life
Externí odkaz:
https://doaj.org/article/e88a25805a484c6d9eb8c2de3fe89c33
Autor:
Yoshiyuki Henning, Christiane Vole, Sabine Begall, Martin Bens, Martina Broecker-Preuss, Arne Sahm, Karol Szafranski, Hynek Burda, Philip Dammann
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113698 (2014)
Ansell's mole-rats (Fukomys anselli) are subterranean, long-lived rodents, which live in eusocial families, where the maximum lifespan of breeders is twice as long as that of non-breeders. Their metabolic rate is significantly lower than expected bas
Externí odkaz:
https://doaj.org/article/e741d8cd58674ef99e0a9d7700d10890
Autor:
Lena Mühlenbruch, Tsima Abou-Kors, Marissa L. Dubbelaar, Leon Bichmann, Oliver Kohlbacher, Martin Bens, Jaya Thomas, Jasmin Ezić, Johann M. Kraus, Hans A. Kestler, Adrian von Witzleben, Joannis Mytilineos, Daniel Fürst, Daphne Engelhardt, Johannes Doescher, Jens Greve, Patrick J. Schuler, Marie-Nicole Theodoraki, Cornelia Brunner, Thomas K. Hoffmann, Hans-Georg Rammensee, Juliane S. Walz, Simon Laban
Publikováno v:
British Journal of Cancer. 128:1777-1787
Background The immune peptidome of OPSCC has not previously been studied. Cancer-antigen specific vaccination may improve clinical outcome and efficacy of immune checkpoint inhibitors such as PD1/PD-L1 antibodies. Methods Mapping of the OPSCC HLA lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dced82b3d981ef6845aecbb8f9e667e6
https://doi.org/10.1038/s41416-023-02197-y
https://doi.org/10.1038/s41416-023-02197-y