Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Martin Bartošík"'
Autor:
Andrea Martisova, Jitka Holcakova, Nasim Izadi, Ravery Sebuyoya, Roman Hrstka, Martin Bartosik
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4247 (2021)
DNA methylation, i.e., addition of methyl group to 5′-carbon of cytosine residues in CpG dinucleotides, is an important epigenetic modification regulating gene expression, and thus implied in many cellular processes. Deregulation of DNA methylation
Externí odkaz:
https://doaj.org/article/cbed9493b14d4569bee142cb53a9f43c
Autor:
Roman Hrstka, Hana Skoupilová, Martin Bartošík, Lucia Sommerová, Jindřich Karban, Jiří Pinkas
Publikováno v:
Proceedings, Vol 22, Iss 1, p 16 (2019)
Chemotherapy is an essential treatment that still plays a vital role in cancer treatment worldwide. The ferrocene derivatives of the general formula [Fe{(η5‑C5H4CH2(p‑C6H4)CH2(N‑het)}2] bearing modified six and five membered N-heterocycles wer
Externí odkaz:
https://doaj.org/article/c473c538cb2647139c435c1c2a3070cc
Publikováno v:
Diagnostics.
Autor:
Tomáš Vaculovič, Donát Gelle, Karel Mach, Andrea Martisova, Roman Hrstka, Viktor Kanický, Lucia Sommerova, Martin Lamač, Ludmila Šimková, Jiří Pinkas, Róbert Gyepes, Martin Bartošík
Publikováno v:
ChemPlusChem. 85:1034-1043
Publikováno v:
Analytical Methods. 12:822-829
Cervical cancer is caused by a persistent infection with high-risk types of human papillomaviruses (HPVs), especially HPV16 and HPV18. HPV testing therefore represents an important alternative to standard cytological screening. However, existing HPV
Autor:
Martin Bartošík, Juan José Montoya, María Pedrero, Susana Campuzano, Maria Gamella, Eloy Povedano, Víctor Ruiz-Valdepeñas Montiel, Verónica Serafín, Paloma Yáñez-Sedeño, Ludmila Moranova, José M. Pingarrón
Publikováno v:
Analytical and Bioanalytical Chemistry. 412:5031-5041
This paper reports a simple electrochemical strategy for the determination of microRNAs (miRNAs) using a commercial His-Tag-Zinc finger protein (His-Tag-ZFP) that binds preferably (but non-sequence specifically) RNA hybrids over ssRNAs, ssDNAs, and d
Publikováno v:
Talanta. 238(Pt 2)
Current molecular diagnostics of prostate cancer relies on detection of elevated levels of PSA protein in serum, but its specificity has been questioned due to its higher levels also in non-malignant prostate diseases. A long non-coding RNA biomarker
Publikováno v:
Analytica chimica acta. 1187
Electrochemical (EC) detection of DNA biomarkers represents an interesting tool in molecular oncology due to its sensitivity, simplicity, low cost or rapid times of measurement. However, majority of EC assays, same as most optical-based techniques, r
Publikováno v:
Electroanalysis. 31:1895-1900
Autor:
Ludmila Jiráková, Martin Bartošík
Publikováno v:
Current Opinion in Electrochemistry. 14:96-103
In recent years, a huge progress has been made regarding the development of electrochemical (EC) assays for detection of nucleic acids — DNA or RNA — as potential cancer biomarkers. Various ingenious strategies for determination of DNA methylatio