Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Martin Bajecny"'
Autor:
Martin Báječný, Chia-Ling Chen, Kateřina Faltusová, Tomáš Heizer, Katarína Szikszai, Petr Páral, Luděk Šefc, Emanuel Nečas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The immense regenerative power of hematopoietic tissue stems from the activation of the immature stem cells and the progenitor cells. After partial damage, hematopoiesis is reconstituted through a period of intense regeneration when blood cell produc
Externí odkaz:
https://doaj.org/article/58bbcd4dfb8d4c64aba542309a32e488
Autor:
Kateřina Faltusová, Chia-Ling Chen, Tomáš Heizer, Martin Báječný, Katarina Szikszai, Petr Páral, Filipp Savvulidi, Nicol Renešová, Emanuel Nečas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Regeneration of severely damaged adult tissues is currently only partially understood. Hematopoietic tissue provides a unique opportunity to study tissue regeneration due to its well established steady-state structure and function, easy accessibility
Externí odkaz:
https://doaj.org/article/4939193a85364d2880cd43a3d6126484
Autor:
Betty Berezovsky, Martin Báječný, Jana Frýdlová, Iuliia Gurieva, Daniel Wayne Rogalsky, Petr Přikryl, Vít Pospíšil, Emanuel Nečas, Martin Vokurka, Jan Krijt
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8209 (2021)
Erythropoietin (EPO) downregulates hepcidin expression to increase the availability of iron; the downregulation of hepcidin is mediated by erythroferrone (ERFE) secreted by erythroblasts. Erythroblasts also express transferrin receptor 2 (TFR2); howe
Externí odkaz:
https://doaj.org/article/572a3dd4dd8340ccafce2a1d128a5e36
Autor:
Jan Krijt, Jana Frýdlová, Iuliia Gurieva, Petr Přikryl, Martin Báječný, Andrea U. Steinbicker, Martin Vokurka, Jaroslav Truksa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2650 (2021)
Matriptase-2, a serine protease expressed in hepatocytes, is a negative regulator of hepcidin expression. The purpose of the study was to investigate the interaction of matriptase-2 with hemojuvelin protein in vivo. Mice lacking the matriptase-2 prot
Externí odkaz:
https://doaj.org/article/0b7d040815df4f9b80b8dcf244771ec5
Autor:
Elena Golovina, Tomas Heizer, Lenka Daumova, Martin Bajecny, Simona Fontana, Valentina Griggio, Rebecca Jones, Marta Coscia, Chiara Riganti, Karina Savvulidi Vargova
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Hypoxia represents one of the key factors that stimulates the growth of leukemic cells in their niche. Leukemic cells in hypoxic conditions are forced to reprogram their original transcriptome, miRNome, and metabolome. How the coupling of mi
Externí odkaz:
https://doaj.org/article/7a94bdf3a2954ff5803329b72cdc9387
Autor:
Miroslav Vetrik, Jan Kucka, Libor Kobera, Rafal Konefal, Volodymyr Lobaz, Ewa Pavlova, Martin Bajecny, Tomas Heizer, Jiri Brus, Ludek Sefc, Guillem Pratx, Martin Hruby
Publikováno v:
Free Radical Biology and Medicine. 187:132-140
Radiation resistance of cancer cells represents one of the major challenges in cancer treatment. The novel self-assembled fluoralkylated diselenide nanoparticles (fluorosomes) based on seleno-l-cystine (17FSe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac2906a6063f67d354bc75cad09fa77
https://doi.org/10.1016/j.freeradbiomed.2022.05.015
https://doi.org/10.1016/j.freeradbiomed.2022.05.015
Hypoxia represents one of the key factors that stimulate the growth of leukemic cells in their niche. Leukemic cells in hypoxia are forced to reprogram their original transcriptome, miRNome, and metabolome. How the coupling of miRNAs/mRNAs helps to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c1007fac4eb4705213d6de93d64791
https://doi.org/10.20944/preprints202304.1197.v1
https://doi.org/10.20944/preprints202304.1197.v1
Autor:
Kateřina Faltusová, Martin Báječný, Tomáš Heizer, Petr Páral, Chia-Ling Chen, Katarína Szikszai, Pavel Klener, Emanuel Nečas
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In bone marrow transplantation (BMT), hematopoiesis-reconstituting cells are introduced following myeloablative treatment, which eradicates existing hematopoietic cells and disrupts stroma within the hematopoietic tissue. Both hematopoietic cells and
Externí odkaz:
https://doaj.org/article/b51d5061b3054bf6a21ac73645e44c81