Rationale for phosphodiesterase-4 inhibition as a treatment strategy for interstitial lung diseases associated with rheumatic diseases

Autor: Elizabeth R Volkmann, Oliver Distler, Martin Aringer, Anna-Maria Hoffmann-Vold, Masataka Kuwana, Helmut Prosch

Publikováno v: RMD Open, Vol 10, Iss 4 (2024)

Interstitial lung disease (ILD) associated with rheumatoid arthritis or with connective tissue diseases such as systemic sclerosis can be collectively named systemic autoimmune rheumatic disease-associated ILDs (SARD-ILDs) or rheumatic musculoskeleta

Externí odkaz: https://doaj.org/article/c64d9325ec0848f38fc2fa938bd12b66

P6 Increased interleukin-6 (IL-6) receptor shedding under interferon-α and IL-6 explains the relatively low C-reactive protein (CRP) levels in SLE patients

Autor: Martin Aringer, Nicolai Leuchten, Adelheid Korb-Pap, Babett Heschel, Annika Krause, Martyna Hempel, Erik Klapproth, Ali El-Amouche

Publikováno v: Lupus Science and Medicine, Vol 11, Iss Suppl 1 (2024)

Externí odkaz: https://doaj.org/article/392d8230f84b4b15b88e3ceb41b54386

Severe methotrexate toxicity in elderly patients under diuretics

Autor: Martin Aringer, Nicolai Leuchten, Kristine Herrmann, Cara Kumar, Matthias Kuhn

Publikováno v: RMD Open, Vol 10, Iss 1 (2024)

Objectives To explore the toxicity of low-dose methotrexate (MTX), an uncommon, but life-threatening event.Methods We analysed the presentation, course and risk factors of all patients admitted to the rheumatology ward with severe low-dose MTX toxici

Externí odkaz: https://doaj.org/article/148cd26e87cb46b2af0c0a60dcd22c58

Burden of systemic lupus erythematosus in clinical practice: baseline data from the SLE Prospective Observational Cohort Study (SPOCS) by interferon gene signature

Autor: Richard Furie, Raj Tummala, Laurent Arnaud, Eric F Morand, Martin Aringer, Barnabas Desta, Bo Ding, Christine Peschken, Jacob Knagenhjelm, Heide A Stirnadel-Farrant, Eleni Rapsomaniki, Jonatan Hedberg, Caroline Seo, Tina Grünfeld Eén, Alessandro Sorrentino

Publikováno v: Lupus Science and Medicine, Vol 10, Iss 2 (2023)

Objective The longitudinal Systemic Lupus Erythematosus Prospective Observational Cohort Study (SPOCS) aims to assess SLE disease course overall and according to type I interferon 4 gene signature (IFNGS). Here, we describe SPOCS patient characterist

Externí odkaz: https://doaj.org/article/55d6932a80014f9ca045e484dc68a166

Characteristics and outcomes of SARS-CoV-2 breakthrough infections among double-vaccinated and triple-vaccinated patients with inflammatory rheumatic diseases

Autor: Tobias Alexander, Hendrik Schulze-Koops, Ulf Müller-Ladner, Rebecca Fischer-Betz, Martin Aringer, Rieke Alten, Petra Saar, Tim Schmeiser, Marina Backhaus, Stephanie Finzel, Cornelia Glaser, Hildrun Haibel, Hanns-Martin Lorenz, Gamal Chehab, Christof Specker, Reinhard E Voll, Anja Strangfeld, Norbert Blank, Matthias Braun, Alexander Pfeil, Rebecca Hasseli, Andreas Krause, Anne Constanze Regierer, Peer Aries, Ioana Andreica, Jacqueline Detert, Elvira Decker, Urs Hartmann, Joerg Henes, Kirsten de Groot, JOACHIM GEORGI, Hans Bastian, Christoph Fiehn, Martin Feuchtenberger, Martin Fleck, Christian Blum, Mathias Grunke, Martin Bohl-Bühler, Georg Gauler, Bimba Franziska Hoyer, Guido Hoese, Janine Günther, Matthias Braunisch, Jutta G. Richter, Sabine Reckert, Anett Gräßler, Andreas Kapelle, Silke Osiek, Anna Knothe, Jan Brandt-Jürgens, Anja Maltzahn, Fredrik Albach, Annette Alberding, Susanne Aman, Christopher Amberger, Michaela Amberger, Bianka Andermann, Nils Anders, Jan Andresen, Nikolaos Andriopoulos, Elizabeth Arauj, Uta Arndt, Sarah Avemarg, Christoph Baerwald, Erich Bärlin, Nora Bartholomä, Michael Bäuerle, Jutta Bauhammer, Christine Baumann, Klaus Becker, Heidemarie Becker, Michaela Bellm, Sylvia Berger, Andrea Berghofen, Gerhard Birkner, Daniel Blendea, Hans Bloching, Sebastian Blötz, Stephanie Boeddeker, Susanne Bogner, Lara Bohnen, Ilka Bösenberg, Nicole Böttcher, Diana Braun, Jan Philipp Bremer, Matthias Broll, Andreas Bruckner, Veronika Brumberger, Martin Brzank, Sahra Büllesfeld, Sandra Burger, Michaela Christenn, Anne Claußnitzer, Frank Demtröder, Rainer Dörfler, Elke Drexler, Valeria Dudics, Edmund Edelmann, Roman Eder, Christina Eisterhues, Joachim Michael Engel, Brigitte Erbslöh-Möller, Miriam Feine, Samantha Ferdinan, Claudia Franke, Stefanie Freudenberg, Christian Fräbel, Petra Fuchs, Regina Gaissmaier, Ino Gao, Oliver Gardt, Katrin Geißler, Karolina Gente, Jasmin Gilly, Yannik Gkanatsas, Agnes Gniezinski- Schwister, Rahel Gold, Norman Görl, Ralf Görlitz, Karl-Heinz Göttl, Beate Göttle, Ricardo Grieshaber Bouyer, Gisela Grothues, Florian Günther, Mirjam Haag, Linda Haas, Anna Haas-Wöhrle, Denitsa Hadjiski, Till Hallmann-Böhm, Peter Härle, Charlotte Hasenkamp, Maura-Maria Hauf, Matthias Hauser

Publikováno v: RMD Open, Vol 9, Iss 2 (2023)

Objective To analyse the clinical profile of SARS-CoV-2 breakthrough infections in at least double-vaccinated patients with inflammatory rheumatic diseases (IRDs).Methods Data from the physician-reported German COVID-19-IRD registry collected between

Externí odkaz: https://doaj.org/article/bcd65462c49f49369021f75255aee09c