Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Martin Ambrož"'
Autor:
Diana Dimunová, Martina Navrátilová, Pavlína Kellerová, Martin Ambrož, Lenka Skálová, Petra Matoušková
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 19, Iss , Pp 56-64 (2022)
Albendazole (ABZ) is an anthelmintic frequently used to treat haemonchosis, a common parasitosis of ruminants caused by the gastrointestinal nematode Haemonchus contortus. This parasite is able to protect itself against ABZ via the formation of inact
Externí odkaz:
https://doaj.org/article/c645fcaf340349f6b61b66e8c3e43697
Autor:
Kristen Kurtzeborn, Hyuk Nam Kwon, Vladislav Iaroshenko, Imrul Faisal, Martin Ambrož, Xing Jin, Talha Qureshi, Jussi Kupari, Anneliis Ihermann-Hella, Juho Väänänen, Henna Tyynismaa, Iva Boušová, Sunghyouk Park, Satu Kuure
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-22 (2022)
Abstract Background MAPK/ERK signaling is a well-known mediator of extracellular stimuli controlling intracellular responses to growth factors and mechanical cues. The critical requirement of MAPK/ERK signaling for embryonic stem cell maintenance is
Externí odkaz:
https://doaj.org/article/94c1978dcb1846ffb998a1dee09b40f6
Autor:
Martin Ambrož, Iva Boušová, Adam Skarka, Veronika Hanušová, Věra Králová, Petra Matoušková, Barbora Szotáková, Lenka Skálová
Publikováno v:
Molecules, Vol 20, Iss 8, Pp 15343-15358 (2015)
The sesquiterpenes β-caryophyllene, β-caryophyllene oxide (CAO), α-humulene (HUM), trans-nerolidol (NER), and valencene (VAL) are substantial components of the essential oil from Myrica rubra leaves which has exhibited significant antiproliferativ
Externí odkaz:
https://doaj.org/article/9c4231aaf30c4499bbede29955264672
Publikováno v:
Genes, Vol 10, Iss 10, p 763 (2019)
The selection of a suitable combination of reference genes (RGs) for data normalization is a crucial step for obtaining reliable and reproducible results from transcriptional response analysis using a reverse transcription-quantitative polymerase cha
Externí odkaz:
https://doaj.org/article/3ddd7cd063f4469aaea50cf022e9b65f
Publikováno v:
Nutrients, Vol 11, Iss 4, p 879 (2019)
Beer, the most popular beverage containing hops, is also frequently consumed by cancer patients. Moreover, non-alcoholic beer, owing to its nutritional value and high content of biological active compounds, is sometimes recommended to patients by onc
Externí odkaz:
https://doaj.org/article/a48f71b835544099b4aae21b9b21058a
Autor:
Alena Špičáková, Barbora Szotáková, Diana Dimunová, Zuzana Myslivečková, Vladimír Kubíček, Martin Ambrož, Kateřina Lněničková, Kristýna Krasulová, Pavel Anzenbacher, Lenka Skálová
Publikováno v:
Molecules, Vol 22, Iss 4, p 509 (2017)
Sesquiterpenes, 15-carbon compounds formed from three isoprenoid units, are the main components of plant essential oils. Sesquiterpenes occur in human food, but they are principally taken as components of many folk medicines and dietary supplements.
Externí odkaz:
https://doaj.org/article/bb206f13e50842639876f47f57e75b1e
Autor:
Diana Dimunová, Petra Matoušková, Martina Navrátilová, Linh Thuy Nguyen, Martin Ambrož, Ivan Vokřál, Barbora Szotáková, Lenka Skálová
Publikováno v:
Science of The Total Environment. 822:153527
Veterinary anthelmintics excreted from treated animals pass to soil, subsequently to plants and then to their consumers. This circulation might have various consequences, including drug-resistance promotion in helminths. The present study was designe
Autor:
Tommy A. Karlsen, Martin Ambrož, Petra Matoušková, Lenka Skálová, Iva Boušová, Barbora Hanousková, Gabriela Vávrová
Publikováno v:
Biochimica et biophysica acta. Gene regulatory mechanisms. 1864(10)
Glutathione peroxidase 7 (GPx7) acts as an intracellular stress sensor/transmitter and plays an important role in adipocyte differentiation and the prevention of obesity related pathologies. For this reason, finding the regulatory mechanisms that con
Autor:
Veronika Hanušová, Martin Ambrož, Petra Matoušková, Tomáš Zárybnický, Kateřina Lněničková, Lucie Raisová Stuchlíková, Zdeněk Šubrt, Lenka Skálová, Věra Králová
Publikováno v:
Drug Testing and Analysis. 10:1139-1146
Flubendazole (FLU), a benzimidazole anthelmintic drug widely used in veterinary medicine, has been approved for the treatment of gut-residing nematodes in humans. In addition, FLU is now considered a promising anti-cancer agent. Despite this, informa
Autor:
Quynh Anh Vu, Roberta Rocca, Fernanda Borges, Martin Ambrož, Tiago H. Silva, Katarína Svrčková, Václav Pflégr, Stefano Alcaro, Martin Krátký, Annalisa Maruca, Šárka Štěpánková, Jarmila Vinšová
Publikováno v:
Bioorganic Chemistry. 116:105301
A combination of several pharmacophores in one molecule has been successfully used for multi-target-directed ligands (MTDL) design. New propargylamine substituted derivatives combined with salicylic and cinnamic scaffolds were designed and synthesize