Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Martin A. Javors"'
Autor:
Dennis M. Minton, Christian J. Elliehausen, Martin A. Javors, Kelly S. Santangello, Adam R. Konopka
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background The objective of this study was to determine if mechanistic target of rapamycin (mTOR) inhibition with or without AMP-activated protein kinase (AMPK) activation can protect against primary, age-related OA. Design Dunkin-Hartley gu
Externí odkaz:
https://doaj.org/article/daa2a283515e4fd284e082004e71767e
Autor:
Richard A. Miller, David E. Harrison, David B. Allison, Molly Bogue, Lucas Debarba, Vivian Diaz, Elizabeth Fernandez, Andrzej Galecki, W. Timothy Garvey, Hashan Jayarathne, Navasuja Kumar, Martin A. Javors, Warren C. Ladiges, Francesca Macchiarini, James Nelson, Peter Reifsnyder, Nadia A. Rosenthal, Marianna Sadagurski, Adam B. Salmon, Daniel L. Smith Jr., Jessica M. Snyder, David B. Lombard, Randy Strong
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Canagliflozin (Cana) is an FDA-approved diabetes drug that protects against cardiovascular and kidney diseases. It also inhibits the sodium glucose transporter 2 by blocking renal reuptake and intestinal absorption of glucose. In the context of the m
Externí odkaz:
https://doaj.org/article/8346a43abd5742d2afbdcea95b0aa4d1
Autor:
Dennis M. Minton, Christian J. Elliehausen, Martin A. Javors, Kelly S. Santangelo, Adam R. Konopka
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/693ef9745a2447b6a34c3b6b410e2075
Autor:
Julianne D. Jett, Rachael Beck, Diana Tyutyunnyk, Jesus Sanchez, Marisa Lopez‐Cruzan, Brett C. Ginsburg, Sterling M. McPherson, Martin A. Javors, Michael G. McDonell, Nathalie Hill‐Kapturczak
Publikováno v:
Alcohol: Clinical and Experimental Research. 47:748-755
Autor:
Alan L, Peterson, Tabatha H, Blount, Edna B, Foa, Lily A, Brown, Carmen P, McLean, Jim, Mintz, Richard P, Schobitz, Bryann R, DeBeer, Joseph, Mignogna, Brooke A, Fina, Wyatt R, Evans, Samantha, Synett, Brittany N, Hall-Clark, Timothy O, Rentz, Christian, Schrader, Jeffrey S, Yarvis, Katherine A, Dondanville, Hunter, Hansen, Vanessa M, Jacoby, Jose, Lara-Ruiz, Casey L, Straud, Willie J, Hale, Dhiya, Shah, Lauren M, Koch, Kelsi M, Gerwell, Stacey, Young-McCaughan, Brett T, Litz, Eric C, Meyer, Abby E, Blankenship, Douglas E, Williamson, John D, Roache, Martin A, Javors, Allah-Fard M, Sharrieff, Barbara L, Niles, Terence M, Keane
Publikováno v:
JAMA network open. 6(1)
Improved, efficient, and acceptable treatments are needed for combat-related posttraumatic stress disorder (PTSD).To determine the efficacy of 2 compressed prolonged exposure (PE) therapy outpatient treatments for combat-related PTSD.This randomized
Autor:
Randy Strong, Richard A. Miller, Catherine J. Cheng, James F. Nelson, Jonathan Gelfond, Shailaja Kesaraju Allani, Vivian Diaz, Angela Olsen Dorigatti, Jonathan Dorigatti, Elizabeth Fernandez, Andrzej Galecki, Brett Ginsburg, Karyn L. Hamilton, Martin A. Javors, Kerry Kornfeld, Matt Kaeberlein, Suja Kumar, David B. Lombard, Marisa Lopez‐Cruzan, Benjamin F. Miller, Peter Rabinovitch, Peter Reifsnyder, Nadia A. Rosenthal, Molly A. Bogue, Adam B. Salmon, Yousin Suh, Eric Verdin, Herbert Weissbach, John Newman, Francesca Maccchiarini, David E. Harrison
Publikováno v:
Aging Cell. 21
Mice bred in 2017 and entered into the C2017 cohort were tested for possible lifespan benefits of (R/S)-1,3-butanediol (BD), captopril (Capt), leucine (Leu), the Nrf2-activating botanical mixture PB125, sulindac, syringaresinol, or the combination of
Autor:
Martin A. Javors, Randy Strong, Gene Hubbard, James F. Nelson, Jonathan Gelfond, Elizabeth Fernandez, James D. Lechleiter, Yuji Ikeno, Veronica Galvan, Adam B. Salmon, Marisa Lopez-Cruzan, Nicolas Musi, Brett C. Ginsburg, Peter J. Hornsby
Publikováno v:
GeroScience
With evolving cores, enrichment and training programs, and supported research projects, the San Antonio (SA) Nathan Shock Center has for 26 years provided critical support to investigators locally, nationally, and abroad. With its existing and growin
Autor:
Kathleen A. Grant, Martin A. Javors, Brett C. Ginsburg, Wouter Koek, Nicole A.R. Walter, Jesus J. Sanchez, Vanessa A. Jimenez, Marisa Lopez-Cruzan
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND Phosphatidylethanol (PEth) homologs are ethanol metabolites used to identify and monitor alcohol drinking in humans. In this study, we measured levels of the 2 most abundant homologs, PEth 16:0/18:1 and PEth 16:0/18:2, in whole blood sampl
Autor:
Manish Parihar, Randy Strong, Martin A. Javors, Zelton D Sharp, Paul Hasty, Gene Hubbard, Sherry G. Dodds
Publikováno v:
Clin Colorectal Cancer
MICRO: Rapamycin extends life and health span in wild type mice suggesting prevention of cancer. We show rapamycin extends survival in colon cancer prone mice and that crypt cells are primary targets of mTOR inhibition that mediate tumor prevention o
Autor:
Julianne L. Price, David Leonard, Carol S. North, Bryon Adinoff, Alice Zhang, Martin A. Javors, Alina M Suris
Publikováno v:
Alcoholism: Clinical and Experimental Research. 44:1192-1203
BACKGROUND Individuals with alcohol use disorder (AUD) and those who have experienced traumas or chronic stress exhibit dysregulated hypothalamic-pituitary-adrenal (HPA) axis reactivity. Whether and how trauma and stress histories interact with AUD t