Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Martin A. Apple"'
3
Creating a strategy for science-based national policy: Addressing conflicting views on the health risk of low-level ionizing radiation. Final report, Wingspread Conference
Autor: Roger O. McClellan, Martin A. Apple
Significant cancer risk for adults exposed to more than 100 millisieverts (10 REM) of ionizing radiation. More research on low-level ionizing radiation is needed in molecular and cellular mechanisms of injury and ongoing exposed populations. Implemen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1cf9ea8fa202b4595a44b236c2a92469
https://doi.org/10.2172/755413
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5
An NMR study of the interaction of daunomycin with dinucleotides and dinucleoside phosphates
Autor: Peter A. Kollman, Thomas L. James, Merrill E. Nuss, Martin A. Apple
Publikováno v: Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 609:136-147
The mode of action of the widely used anticancer drug daunomycin was studied by 360 MHz and 100 MHz proton NMR. Information obtained from scalar coupling constants indicates that the conformation of the A ring of the aglycone moiety of daunomycin is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa4b4c2a5d21bd5000f087239fbd80f
https://doi.org/10.1016/0005-2787(80)90207-5
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6
New Anticancer Drug Design: Past and Future Strategies
Autor: Martin A. Apple
Publikováno v: Chemotherapy ISBN: 9781461566304
The current strategies we have used for the conquest of the advanced cancer, i.e., one big enough to see, have involved less planned strategy and more the historical accretion of procedures such as surgery (Veronesi, 1973), radiation therapy (Kligerm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b24406707c237caed0029f833a0aee31
https://doi.org/10.1007/978-1-4615-6628-1_20
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7
Production, Isolation, and Properties of Azetomycins
Autor: Joseph V. Formica, Martin A. Apple
Streptomyces antibioticus synthesizes five actinomycins that differ in the “proline site” of the molecule. When cultured in the presence of azetidine-2-carboxylic acid (AzC), antibiotic synthesis was stimulated 40 to 50%, synthesis of actinomycin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8671793b9338504a040d6b6ee3d06e
https://europepmc.org/articles/PMC429506/
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9
Refractory megaloblastic anemia with myeloperoxidase-deficient neutrophils
Autor: N. Paul Rosenthal, Martin A. Apple, Leonard S. Goldberg, Robert I. Lehrer
Publikováno v: Annals of internal medicine. 76(3)
The enzyme myeloperoxidase contributes to the ability of human leukocytes to kill fungi and bacteria. We studied a 61-year-old man with megaloblastic anemia and two populations of neutroph...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9064c3918d2b58ae69f514aa90655ee5
https://pubmed.ncbi.nlm.nih.gov/5015919
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