Zobrazeno 1 - 10
of 366
pro vyhledávání: '"Martin A Maier"'
Publikováno v:
ChemistryOpen, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Among the natural tetramic acids with a decalinoyl part, signermycin B is unique because it contains a cis‐decalin. In this paper, we demonstrate that the cis‐decalin section of signermycin B can be accessed by an anionic oxy‐Cope rear
Externí odkaz:
https://doaj.org/article/e7d4ed1d4c6147a299a2722ba76c9da8
Autor:
Martin G. Maier
Publikováno v:
Zeitschrift für Rechtsextremismusforschung, Vol 4, Iss 1-2024, Pp 119-135 (2024)
In jüngster Zeit beziehen sich Querfrontkonzepte weniger nur auf organisationsbezogene Überlegungen, sondern werden als Teil einer rechtspopulistischen Mobilisierungsstrategie der ‚hart arbeitenden normalen Leute‘ gegen die ‚korrupten interna
Externí odkaz:
https://doaj.org/article/a8180a87537d41c08d4d6357aebe4483
Autor:
Barbara L Mui, Ying K Tam, Muthusamy Jayaraman, Steven M Ansell, Xinyao Du, Yuen Yi C Tam, Paulo JC Lin, Sam Chen, Jayaprakash K Narayanannair, Kallanthottathil G Rajeev, Muthiah Manoharan, Akin Akinc, Martin A Maier, Pieter Cullis, Thomas D Madden, Michael J Hope
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Lipid nanoparticles (LNPs) encapsulating short interfering RNAs that target hepatic genes are advancing through clinical trials, and early results indicate the excellent gene silencing observed in rodents and nonhuman primates also translates to huma
Externí odkaz:
https://doaj.org/article/f5677ebf4c334dbe9c9d38a4979393bb
Autor:
Megha Subramanian, James McIninch, Ivan Zlatev, Mark K. Schlegel, Charalambos Kaittanis, Tuyen Nguyen, Saket Agarwal, Timothy Racie, Martha Arbaiza Alvarado, Kelly Wassarman, Thomas S. Collins, Tyler Chickering, Christopher R. Brown, Karyn Schmidt, Adam B. Castoreno, Svetlana Shulga-Morskaya, Elena Stamenova, Kira Buckowing, Daniel Berman, Joseph D. Barry, Anna Bisbe, Martin A. Maier, Kevin Fitzgerald, Vasant Jadhav
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Here the authors propose an RNA interference-based switch for dynamic control of AAV transgene expression. In this approach, transgene expression may be silenced by RNAi and subsequently recovered using REVERSIR oligonucleotides.
Externí odkaz:
https://doaj.org/article/0fc8fb8623c24daabbd0601f2495d2bc
Autor:
Jan G. Felber, Lena Poczka, Karoline C. Scholzen, Lukas Zeisel, Martin S. Maier, Sander Busker, Ulrike Theisen, Christina Brandstädter, Katja Becker, Elias S. J. Arnér, Julia Thorn-Seshold, Oliver Thorn-Seshold
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Cyclic five-membered disulfides (1,2-dithiolanes) have been reported either as nonspecific redox motifs, or as highly specific cellular probes for thioredoxin reductase (TrxR). Here the authors show that 1,2-dithiolane probes are nonspecifically redu
Externí odkaz:
https://doaj.org/article/d91e7f3ce64641b1a587ffd99090ce7f
Autor:
Marc Halang, Prof. Dr. Martin E. Maier
Publikováno v:
ChemistryOpen, Vol 11, Iss 10, Pp n/a-n/a (2022)
Abstract The generation of the quaternary stereocenter at the C9 position of salvinorin A precursors by the Claisen rearrangement was investigated. The required allyl alcohol was prepared from a Wieland‐Miescher ketone using a known γ‐hydroxylat
Externí odkaz:
https://doaj.org/article/ca50bd4168444a569d7c2b777341ef09
Autor:
Laura de Andrade Souza, Edson Luiz Francisquetti, Rafael Domingos Dalagnol, Celso Roman Junior, Maria Telma Gomes Schanz, Martin Edmund Maier, Cesar Liberato Petzhold
Publikováno v:
Polímeros, Vol 31, Iss 2 (2021)
Abstract A new oleic acid derivative plasticizer, epoxidized trimethylolpropane trioleate (EPO), has been synthesized and its application in PVC formulations compared with di(2-ethylhexyl) 1,2-cyclohexanoate (DOCH/DEHCH), a commercial phthalate-free
Externí odkaz:
https://doaj.org/article/21c76129143d4315b60e902f6e730629
Autor:
Jan G. Felber, Annabel Kitowski, Lukas Zeisel, Martin S. Maier, Constanze Heise, Julia Thorn-Seshold, Oliver Thorn-Seshold
Publikováno v:
ACS Central Science. 9:763-776
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d829392534ca41fcf0f8ccc517c5b0f4
https://doi.org/10.1021/acscentsci.2c01465
https://doi.org/10.1021/acscentsci.2c01465
Autor:
Pachamuthu Kandasamy, Shohei Mori, Shigeo Matsuda, Namrata Erande, Dhrubajyoti Datta, Jennifer L. S. Willoughby, Nate Taneja, Jonathan O’Shea, Anna Bisbe, Rajar M. Manoharan, Kristina Yucius, Tuyen Nguyen, Ramesh Indrakanti, Swati Gupta, Jason A. Gilbert, Tim Racie, Amy Chan, Ju Liu, Renta Hutabarat, Jayaprakash K. Nair, Klaus Charisse, Martin A. Maier, Kallanthottathil G. Rajeev, Martin Egli, Muthiah Manoharan
Publikováno v:
Journal of Medicinal Chemistry. 66:2506-2523
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::815ae0fb669898f37b1e2ab925b10193
https://doi.org/10.1021/acs.jmedchem.2c01337
https://doi.org/10.1021/acs.jmedchem.2c01337
Autor:
Maja M. Janas, Mark K. Schlegel, Carole E. Harbison, Vedat O. Yilmaz, Yongfeng Jiang, Rubina Parmar, Ivan Zlatev, Adam Castoreno, Huilei Xu, Svetlana Shulga-Morskaya, Kallanthottathil G. Rajeev, Muthiah Manoharan, Natalie D. Keirstead, Martin A. Maier, Vasant Jadhav
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
A subset of chemically-modified siRNAs conjugated to trivalent GalNAc may fail during nonclinical development due to rat hepatotoxicity. Here, the authors show that hepatotoxicity may be accounted for by microRNA-like off-target effects of siRNA and
Externí odkaz:
https://doaj.org/article/c6e811a8256f42f19ee8c93f99cf1382