Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Martin A Gorovsky"'
Autor:
Wei Miao, Jie Xiong, Josephine Bowen, Wei Wang, Yifan Liu, Olga Braguinets, Jorg Grigull, Ronald E Pearlman, Eduardo Orias, Martin A Gorovsky
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4429 (2009)
The model eukaryote, Tetrahymena thermophila, is the first ciliated protozoan whose genome has been sequenced, enabling genome-wide analysis of gene expression.A genome-wide microarray platform containing the predicted coding sequences (putative gene
Externí odkaz:
https://doaj.org/article/d7b7c906226947c09ee6416981af0904
Autor:
Jonathan A Eisen, Robert S Coyne, Martin Wu, Dongying Wu, Mathangi Thiagarajan, Jennifer R Wortman, Jonathan H Badger, Qinghu Ren, Paolo Amedeo, Kristie M Jones, Luke J Tallon, Arthur L Delcher, Steven L Salzberg, Joana C Silva, Brian J Haas, William H Majoros, Maryam Farzad, Jane M Carlton, Roger K Smith, Jyoti Garg, Ronald E Pearlman, Kathleen M Karrer, Lei Sun, Gerard Manning, Nels C Elde, Aaron P Turkewitz, David J Asai, David E Wilkes, Yufeng Wang, Hong Cai, Kathleen Collins, B Andrew Stewart, Suzanne R Lee, Katarzyna Wilamowska, Zasha Weinberg, Walter L Ruzzo, Dorota Wloga, Jacek Gaertig, Joseph Frankel, Che-Chia Tsao, Martin A Gorovsky, Patrick J Keeling, Ross F Waller, Nicola J Patron, J Michael Cherry, Nicholas A Stover, Cynthia J Krieger, Christina del Toro, Hilary F Ryder, Sondra C Williamson, Rebecca A Barbeau, Eileen P Hamilton, Eduardo Orias
Publikováno v:
PLoS Biology, Vol 4, Iss 9, p e286 (2006)
The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct nuclei within a single cell. The germline-like micron
Externí odkaz:
https://doaj.org/article/05012f5a3b544655a50cce2f034ce46a
Autor:
Chunchao Zhang, Shan Gao, Yifan Liu, Zhe Wang, Anthony J. Molascon, Philip C. Andrews, Martin A. Gorovsky
Publikováno v:
Journal of Proteome Research
Systems analysis of chromatin has been constrained by complex patterns and dynamics of histone post-translational modifications (PTMs), which represent major challenges for both mass spectrometry (MS) and immuno-based approaches (e.g., chromatin immu
Publikováno v:
Genes & Development. 26:615-629
H2A.Y is an essential, divergent Tetrahymena thermophila histone variant. It has a long nonhistone N terminus that contains leucine-rich repeats (LRR) and an LRR cap domain with similarity to Sds22p, a regulator of yeast protein phosphatase 1 (PP1) a
Autor:
Joseph Fass, Eileen P. Hamilton, Eduardo Orias, Josephine Bowen, Douglas L. Chalker, Mary T. Couvillion, Kathleen Collins, Nikhil Joshi, Jonathan A. Eisen, Martin A. Gorovsky, Robert S. Coyne, Dawei Lin, Kyungah Hong
Publikováno v:
G3: Genes|Genomes|Genetics
Fass, J N, Joshi, N A, Couvillion, M T, Bowen, J, Gorovsky, M A, Hamilton, E P, Orias, E, Hong, K, Coyne, R S, Eisen, J A, Chalker, D L, Lin, D & Collins, K 2011, ' Genome-Scale Analysis of Programmed DNA Elimination Sites in Tetrahymena thermophila ', G3: Genes | Genomes | Genetics, vol. 1, no. 6, pp. 515-22 . https://doi.org/10.1534/g3.111.000927
G3 (Bethesda, Md.), vol 1, iss 6
Fass, J N, Joshi, N A, Couvillion, M T, Bowen, J, Gorovsky, M A, Hamilton, E P, Orias, E, Hong, K, Coyne, R S, Eisen, J A, Chalker, D L, Lin, D & Collins, K 2011, ' Genome-Scale Analysis of Programmed DNA Elimination Sites in Tetrahymena thermophila ', G3: Genes | Genomes | Genetics, vol. 1, no. 6, pp. 515-22 . https://doi.org/10.1534/g3.111.000927
G3 (Bethesda, Md.), vol 1, iss 6
Genetically programmed DNA rearrangements can regulate mRNA expression at an individual locus or, for some organisms, on a genome-wide scale. Ciliates rely on a remarkable process of whole-genome remodeling by DNA elimination to differentiate an expr
Autor:
Dorota Wloga, Bernard Eddé, Juliette van Dijk, Virginie Redeker, Krzysztof Rogowski, Maria Jerka-Dziadosz, Marie-Hélène Bré, Martin A. Gorovsky, Jacek Gaertig, Jianming Duan, Carsten Janke, Neeraj Sharma, Nicolette Levilliers
Publikováno v:
Eukaryotic Cell
Eukaryotic Cell, American Society for Microbiology, 2008, 7 (8), pp.1362-72. ⟨10.1128/EC.00084-08⟩
Eukaryotic Cell, American Society for Microbiology, 2008, 7 (8), pp.1362-72. ⟨10.1128/EC.00084-08⟩
Tubulin undergoes glutamylation, a conserved posttranslational modification of poorly understood function. We show here that in the ciliate Tetrahymena , most of the microtubule arrays contain glutamylated tubulin. However, the length of the polyglut
Autor:
Che-Chia Tsao, Martin A. Gorovsky
Publikováno v:
Journal of Cell Science. 121:428-436
Intraflagellar transport (IFT) moves multiple protein particles composed of two biochemically distinct complexes, IFT-A and IFT-B, bi-directionally within cilia and is essential for cilia assembly and maintenance. We identified an ORF from the Tetrah
Publikováno v:
Molecular and Cellular Biology. 26:7719-7730
In Tetrahymena, HHT1 and HHT2 genes encode the same major histone H3; HHT3 and HHT4 encode similar minor H3 variants (H3s), H3.3 and H3.4. Green fluorescent protein (GFP)-tagged H3 is deposited onto chromatin through a DNA replication-coupled (RC) pa
Autor:
Katrina J. Woolcock, Martin A. Gorovsky, Jan H. Suhren, Kensuke Kataoka, Kazufumi Mochizuki, Tomoko Noto, Azusa Hayashi
Publikováno v:
Molecular Cell
Summary Small RNAs are used to silence transposable elements (TEs) in many eukaryotes, which use diverse evolutionary solutions to identify TEs. In ciliated protozoans, small-RNA-mediated comparison of the germline and somatic genomes underlies ident
Publikováno v:
The Journal of Cell Biology
We have used in vitro mutagenesis and gene replacement to study the function of the nucleotide-binding domain (NBD) of γ-tubulin in Tetrahymena thermophila. In this study, we show that the NBD has an essential function and that point mutations in tw