Zobrazeno 1 - 10 of 210 pro vyhledávání: '"Martin A, Taubman"'
1
Akademický článek
Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer’s disease
Autor: Ingar Olsen, Martin A. Taubman, Sim K. Singhrao
Publikováno v: Journal of Oral Microbiology, Vol 8, Iss 0, Pp 1-13 (2016)
Porphyromonas gingivalis, a keystone pathogen in chronic periodontitis, has been found to associate with remote body organ inflammatory pathologies, including atherosclerosis and Alzheimer’s disease (AD). Although P. gingivalis has a plethora of vi
Externí odkaz: https://doaj.org/article/267f72301d6f4915aa048f12dc837406
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2
Akademický článek
Lipopolysaccharides-Induced Suppression of Innate-Like B Cell Apoptosis Is Enhanced by CpG Oligodeoxynucleotide and Requires Toll-Like Receptors 2 and 4.
Autor: Xiaoqian Yu, Yuhua Wang, Jiang Lin, Yang Hu, Toshihisa Kawai, Martin A Taubman, Xiaozhe Han
Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0165862 (2016)
Innate-like B lymphocytes play an important role in innate immunity in periodontal disease through Toll-like receptor (TLR) signaling. However, it is unknown how innate-like B cell apoptosis is affected by the periodontal infection-associated innate
Externí odkaz: https://doaj.org/article/d6f81e0ad82b4a71a900e8e15daee534
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3
Akademický článek
Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease
Autor: Mikihito Kajiya, Gabriela Giro, Martin A. Taubman, Xiaozhe Han, Marcia P.A. Mayer, Toshihisa Kawai
Publikováno v: Journal of Oral Microbiology, Vol 2, Iss 0, Pp 1-16 (2010)
Accumulated lines of evidence suggest that hyperimmune responses to periodontal bacteria result in the destruction of periodontal connective tissue and alveolar bone. The etiological roles of periodontal bacteria in the onset and progression of perio
Externí odkaz: https://doaj.org/article/5fcddc063480478e88763af662bd9fe9
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4
Akademický článek
Aggregatibacter actinomycetemcomitans Omp29 is associated with bacterial entry to gingival epithelial cells by F-actin rearrangement.
Autor: Mikihito Kajiya, Hitoshi Komatsuzawa, Annatoula Papantonakis, Makoto Seki, Seicho Makihira, Kazuhisa Ouhara, Yutaka Kusumoto, Shinya Murakami, Martin A Taubman, Toshihisa Kawai
Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18287 (2011)
The onset and progressive pathogenesis of periodontal disease is thought to be initiated by the entry of Aggregatibacter actinomycetemcomitans (Aa) into periodontal tissue, especially gingival epithelium. Nonetheless, the mechanism underlying such ba
Externí odkaz: https://doaj.org/article/b1d9fb49330241028f16be3f7e2cd73d
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5
Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor
Autor: Xiaozhe Han, Ayman Al-Dharrab, Frank C. Nichols, Abdulghani I. Mira, Hajime Sasaki, Alexandru Movila, Mohammed Howait, Kenji Egashira, Floyd E. Dewhirst, Toshihisa Kawai, Martin A. Taubman, Rayyan A. Kayal, Marcelo Henrique Napimoga, Hiroyuki Kanzaki
Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1862:452-462
Among several virulence factors produced by the periodontal pathogen Porphyromonas gingivalis (Pg), a recently identified novel class of dihydroceramide lipids that contains a long acyl-chain has the potential to play a pathogenic role in periodontit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73b803ab848db0b56f53dc27e100da7
https://doi.org/10.1016/j.bbalip.2017.01.008
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6
Toll-like receptor agonists Porphyromonas gingivalis LPS and CpG differentially regulate IL-10 competency and frequencies of mouse B10 cells
Autor: Grace Huang, Mei Lin, Martin A. Taubman, Toshihisa Kawai, Pei Yu, Zuomin Wang, Han Xiaozhe, Yang Hu, Zhiqiang Liu
Publikováno v: Journal of Applied Oral Science v.25 n.1 2017
Journal of applied oral science
Universidade de São Paulo (USP)
instacron:USP
Journal of Applied Oral Science
Journal of Applied Oral Science, Vol 25, Iss 1, Pp 90-100
Journal of Applied Oral Science, Volume: 25, Issue: 1, Pages: 100-90, Published: FEB 2017
IL-10 expressing regulatory B cells (B10) play a key role in immune system balance by limiting excessive inflammatory responses. Effects of toll-like receptor signaling and co-stimulatory molecules on B10 activity during innate and adaptive immune re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b907a2af89eee556cc3319b29ee7ff0c
https://doi.org/10.1590/1678-77572016-0277
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7
Soluble RANKL Cleaved from Activated Lymphocytes by TNF-α–Converting Enzyme Contributes to Osteoclastogenesis in Periodontitis
Autor: Toshihisa Kawai, Hani Mawardi, Takenobu Ishii, Maiko Suzuki, Alexandru Movila, Seicho Makihira, Hiroyuki Kanzaki, Xiaozhe Han, Martin A. Taubman, Xiaoping Lin, Josefine Hirschfeld
Publikováno v: The Journal of Immunology. 197:3871-3883
Host immune responses play a key role in promoting bone resorption in periodontitis via receptor activator of NF-κB ligand (RANKL)–dependent osteoclastogenesis. Both membrane-bound RANKL (mRANKL) expressed on lymphocytes and soluble RANKL (sRANKL)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a343888a1be172b81f9012710b504beb
https://doi.org/10.4049/jimmunol.1601114
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8
Robert J. Genco: Pioneer in Oral Science Advancement
Autor: Martin A. Taubman
Publikováno v: Journal of dental research. 97(7)
Professor Robert J. Genco made extraordinary research advances in immunology, periodontology, and microbiology research, pioneering major advances in oral science. In addition to his extraordinary research advancements in oral biology, his pioneering
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe21dc3dfed1d5336864855f7826d708
https://pubmed.ncbi.nlm.nih.gov/29856682
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9
OC-STAMP promotes osteoclast fusion for pathogenic bone resorption in periodontitis via up-regulation of permissive fusogen CD9
Autor: Toshihisa Kawai, Rayyan A. Kayal, Kenji Egashira, Xiaozhe Han, Montserrat Ruiz-Torruella, Satoru Shindo, Wichaya Wisitrasameewong, Alexandru Movila, Hani Mawardi, Takeshi Miyamoto, Takenobu Ishii, Abdullah Albassam, Ayman Al-Dharrab, Martin A. Taubman, Kenta Yamamoto, Kenji Sueishi, Atsushi Ikeda, Abdulghani I. Mira
Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(7)
Cell fusion–mediated formation of multinuclear osteoclasts (OCs) plays a key role in bone resorption. It is reported that 2 unique OC-specific fusogens [i.e., OC-stimulatory transmembrane protein (OC-STAMP) and dendritic cell–specific transmembra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b518bc3d83b264c6d9bcebba553ed910
https://pubmed.ncbi.nlm.nih.gov/29533736
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