Výsledky vyhledávání - "Martin A, Lodge"

Akademický článek

Dynamic 18F-Pretomanid PET imaging in animal models of TB meningitis and human studies

Autor: Filipa Mota, Camilo A. Ruiz-Bedoya, Elizabeth W. Tucker, Daniel P. Holt, Patricia De Jesus, Martin A. Lodge, Clara Erice, Xueyi Chen, Melissa Bahr, Kelly Flavahan, John Kim, Mary Katherine Brosnan, Alvaro A. Ordonez, Charles A. Peloquin, Robert F. Dannals, Sanjay K. Jain

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)

Pretomanid has been approved for use in cases of multi-drug resistant pulmonary tuberculosis, yet the penetration of this antibiotic into other target tissues is not well established. Authors provide insight on pretomanid pharmacokinetics in the cent

Externí odkaz: https://doaj.org/article/f0a782321c4e4e36aa37ab969660b2e2

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Akademický článek

High SUVs Have More Robust Repeatability in Patients with Metastatic Prostate Cancer: Results from a Prospective Test-Retest Cohort Imaged with 18F-DCFPyL

Publikováno v: Molecular Imaging, Vol 2022 (2022)

Objectives. In patients with prostate cancer (PC) receiving prostate-specific membrane antigen- (PSMA-) targeted radioligand therapy (RLT), higher baseline standardized uptake values (SUVs) are linked to improved outcome. Thus, readers deciding on RL

Externí odkaz: https://doaj.org/article/5bfc1256bc1347abb2e5c98b1daffdae

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Test–retest repeatability of organ uptake on PSMA‐targeted 18 F‐DCFPyL PET/CT in patients with prostate cancer

Autor: Rudolf A. Werner, Susanne Lütje, Bilêl Habacha, Lena Bundschuh, Takahiro Higuchi, Andreas K. Buck, Aleksander Kosmala, Constantin Lapa, Markus Essler, Martin A. Lodge, Kenneth J. Pienta, Mario A. Eisenberger, Mark C. Markowski, Michael A. Gorin, Martin G. Pomper, Steven P. Rowe, Ralph A. Bundschuh

Publikováno v: The Prostate.

Objectives We evaluated 18F-DCFPyL test–retest repeatability of uptake in normal organs. Methods Twenty-two prostate cancer (PC) patients underwent two 18F-DCFPyL PET scans within 7 days within a prospective clinical trial (NCT03793543). In both PE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b554bce88166ce3d0431c4dd27bf0c04
https://doi.org/10.1002/pros.24577

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Akademický článek

Effect of Point-Spread Function Reconstruction for Indeterminate PSMA-RADS-3A Lesions on PSMA-Targeted PET Imaging of Men with Prostate Cancer

Autor: Wajahat Khatri, Hyun Woo Chung, Rudolf A. Werner, Jeffrey P. Leal, Kenneth J. Pienta, Martin A. Lodge, Michael A. Gorin, Martin G. Pomper, Steven P. Rowe

Publikováno v: Diagnostics, Vol 11, Iss 4, p 665 (2021)

Purpose: Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) is emerging as an important modality for imaging patients with prostate cancer (PCa). As with any imaging modality, indeterminate findings will arise. The PSMA repo

Externí odkaz: https://doaj.org/article/3818064d15f54a54a0eb6d53e234179a

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Dynamic

Autor: Filipa, Mota, Camilo A, Ruiz-Bedoya, Elizabeth W, Tucker, Daniel P, Holt, Patricia, De Jesus, Martin A, Lodge, Clara, Erice, Xueyi, Chen, Melissa, Bahr, Kelly, Flavahan, John, Kim, Mary Katherine, Brosnan, Alvaro A, Ordonez, Charles A, Peloquin, Robert F, Dannals, Sanjay K, Jain

Publikováno v: Nature communications. 13(1)

Pretomanid is a nitroimidazole antimicrobial active against drug-resistant Mycobacterium tuberculosis and approved in combination with bedaquiline and linezolid (BPaL) to treat multidrug-resistant (MDR) pulmonary tuberculosis (TB). However, the penet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::678e2ebe32005ff8afbcf7782e9e9ca1
https://pubmed.ncbi.nlm.nih.gov/36581633

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Prospective Within-Patient Assessment of the Impact of an Unlabeled Octreotide Pre-dose on the Biodistribution and Tumor Uptake of 68Ga DOTATOC as Assessed by Dynamic Whole-body PET in Patients with Neuroendocrine Tumors: Implications for Diagnosis and Therapy

Autor: Lilja B. Solnes, Muhammad A. Chaudhry, Martin A. Lodge, Richard L. Wahl

Publikováno v: Molecular Imaging and Biology. 23:766-774

Gastroenteropancreatic neuroendocrine tumors (GEP NETs) are often associated with high expression of somatostatin receptors (SSTRs) which allows for PET/CT imaging with radiolabeled somatostatin analogs such as 68Ga-DOTATOC. The interplay between 68G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbfeefbdeb1161e0682fc5c6b03a13fb
https://doi.org/10.1007/s11307-021-01600-5

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PET Imaging of the cannabinoid receptor type 2 in humans using [11C]MDTC

Autor: Yong Du, Jennifer M. Coughlin, Mary Katherine Brosnan, Allen Chen, Laura K. Shinehouse, Rehab Abdallah, Martin A. Lodge, William B. Mathews, Chen Liu, Yunkou Wu, Andrew Hall, Wojciech Lesniak, Robert Dannals, Andrew Horti, Martin Pomper

Purpose: We report findings from the first-in-human study of [ 11 C]MDTC, a radiotracer developed to image the cannabinoid receptor type 2 (CB2R) with positron emission tomography (PET). Methods: Ten healthy adults were imaged according to a 90 min d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::621ad5840c34a6250cd0d1343675e3e5
https://doi.org/10.21203/rs.3.rs-1479303/v1

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