Zobrazeno 1 - 10
of 403
pro vyhledávání: '"Martin Schmelz"'
Publikováno v:
PAIN Reports, Vol 9, Iss 5, p e1190 (2024)
Abstract. Introduction:. Injection of recombinant human nerve growth factor (rhNGF) evokes acute heat and prolonged “polymodal” (mechanosensitive [CM]) and “silent” (mechanoinsensitive [CMi]) C-nociceptor sensitization. Both nociceptor classe
Externí odkaz:
https://doaj.org/article/2994ab5a8e3245a198dc715cf4a6701e
Publikováno v:
PLoS ONE, Vol 19, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/177a3430a7094343a74ff73a619cb077
Autor:
Lina Renkhold, Henning Wiegmann, Bettina Pfleiderer, Aysenur Süer, Claudia Zeidler, Manuel P. Pereira, Martin Schmelz, Sonja Ständer, Konstantin Agelopoulos
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
BackgroundChronic scratching imposes a major stress on the skin and can lead to itch intensity worsening, and consequently, patients may enter an itch–scratch cycle. This repetitive mechanical stress can result in lichenification, worsening of epid
Externí odkaz:
https://doaj.org/article/4a8f456812bc43c19ae399213cef7cd6
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Single intradermal injections of nerve growth factor (NGF) evoke prolonged but temporally distinct sensitization patterns to somatosensory stimuli. Focal administration of the non-histaminergic pruritogen cowhage but not histamine resulted i
Externí odkaz:
https://doaj.org/article/8d4c5dba13f946068dab5b501ebb67c2
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
TRPM3 is a calcium-permeable cation channel expressed in a range of sensory neurons that can be activated by heat and the endogenous steroid pregnenolone sulfate (PS). During inflammation, the expression and function of TRPM3 are both augmented in so
Externí odkaz:
https://doaj.org/article/d79b765d087d4085aebc141836c1fd28
Autor:
Gunther Landmann, Lenka Stockinger, Benjamin Gerber, Justus Benrath, Martin Schmelz, Roman Rukwied
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271327 (2022)
We explored whether increased C-nociceptor excitability predicts analgesic effects of topical lidocaine in 33 patients with mono- (n = 15) or poly-neuropathy (n = 18). Excitability of C-nociceptors was tested by transcutaneous electrical sinusoidal (
Externí odkaz:
https://doaj.org/article/96e5321fab424a328a9541ddcc60e91f
Autor:
Simon Rohner, Martina Gramer, Ivo Wiesweg, Oliver Scherf-Clavel, Peter Wohlsein, Martin Schmelz, Ursula Siebert, Franziska Richter, Manuela Gernert
Publikováno v:
Toxics, Vol 11, Iss 4, p 338 (2023)
Emerging contaminants are produced globally at high rates and often ultimately find their way into the aquatic environment. These include substances contained in anti-seizure medication (ASM), which are currently appearing in surface waters at increa
Externí odkaz:
https://doaj.org/article/3a873981753e48c185d9580bcbebbde9
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/489ade93acc84140b77ec45cc44823b5
Autor:
Gil Yosipovitch, Laurent Misery, Ehrhardt Proksch, Martin Metz, Sonja Ständer, Martin Schmelz
Publikováno v:
Acta Dermato-Venereologica, Vol 99, Iss 13, Pp 1201-1209 (2019)
Barrier damage, dry skin and itch are intricately linked and form the basis of many common skin diseases. Damage from environmental insults, or genetic or inflammatory causes, can impair the skin barrier, resulting in an increase in transepidermal wa
Externí odkaz:
https://doaj.org/article/869d5dc95e6647779db747349aff82f4
Autor:
Manuel P. Pereira, Konstantin Agelopoulos, Johannes Köllner, Gitta Neufang, Martin Schmelz, Sonja Ständer
Publikováno v:
Acta Dermato-Venereologica, Vol 99, Iss 11, Pp 1009-1015 (2019)
Central sensitization induces pain augmentation in chronic pain states. An analogous mechanism is speculated for chronic pruritus. This study compared patients with chronic pruritus (n = 79) of different origins (atopic dermatitis, chronic pruritus o
Externí odkaz:
https://doaj.org/article/79e8985858104db29738c711c3c9099a