Zobrazeno 1 - 10 of 129 pro vyhledávání: '"Martin Oudega"'
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Akademický článek
The Effects of the Combination of Mesenchymal Stromal Cells and Nanofiber-Hydrogel Composite on Repair of the Contused Spinal Cord
Autor: Agnes E. Haggerty, Ines Maldonado-Lasunción, Yohshiro Nitobe, Kentaro Yamane, Megan M. Marlow, Hua You, Chi Zhang, Brian Cho, Xiaowei Li, Sashank Reddy, Hai-Quan Mao, Martin Oudega
Publikováno v: Cells, Vol 11, Iss 7, p 1137 (2022)
A bone marrow-derived mesenchymal stromal cell (MSC) transplant and a bioengineered nanofiber-hydrogel composite (NHC) have been shown to stimulate nervous tissue repair in the contused spinal cord in rodent models. Here, these two modalities were co
Externí odkaz: https://doaj.org/article/aa22a86eeecd4ac7860a7b887676db52
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3
Electrospun fiber-mediated delivery of neurotrophin-3 mRNA for neural tissue engineering applications
Autor: Devan L. Puhl, Jessica L. Funnell, Tanner D. Fink, Anuj Swaminathan, Martin Oudega, R. Helen Zha, Ryan J. Gilbert
Publikováno v: Acta Biomaterialia. 155:370-385
Aligned electrospun fibers provide topographical cues and local therapeutic delivery to facilitate robust peripheral nerve regeneration. mRNA delivery enables transient expression of desired proteins that promote axonal regeneration. However, no prio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b61f778ef2bf5adaf4862be089f4ab0
https://doi.org/10.1016/j.actbio.2022.11.025
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4
Akademický článek
Aligned Fingolimod-Releasing Electrospun Fibers Increase Dorsal Root Ganglia Neurite Extension and Decrease Schwann Cell Expression of Promyelinating Factors
Autor: Devan L. Puhl, Jessica L. Funnell, Anthony R. D’Amato, Jonathan Bao, Dmitri V. Zagorevski, Yelena Pressman, Daniel Morone, Agnes E. Haggerty, Martin Oudega, Ryan J. Gilbert
Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Researchers are investigating the use of biomaterials with aligned guidance cues, like those provided by aligned electrospun fibers, to facilitate axonal growth across critical-length peripheral nerve defects. To enhance the regenerative outcomes fur
Externí odkaz: https://doaj.org/article/40a8c5c463fd45b18cea759c8f74c6c1
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5
Akademický článek
The Effect of Inflammatory Priming on the Therapeutic Potential of Mesenchymal Stromal Cells for Spinal Cord Repair
Autor: Inés Maldonado-Lasunción, Agnes E. Haggerty, Akinori Okuda, Tokumitsu Mihara, Natalia de la Oliva, Joost Verhaagen, Martin Oudega
Publikováno v: Cells, Vol 10, Iss 6, p 1316 (2021)
Mesenchymal stromal cells (MSC) are used for cell therapy for spinal cord injury (SCI) because of their ability to support tissue repair by paracrine signaling. Preclinical and clinical research testing MSC transplants for SCI have revealed limited s
Externí odkaz: https://doaj.org/article/c99f95eb7fff4931b4b8499b4b0a58c4
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7
Contributors
Autor: Ana A. Aldana, Morgan R. Alexander, Anthony Atala, Stephen F. Badylak, Matthew B. Baker, Jurica Bauer, Cameron Black, Sharan Bobbala, Mats Brittberg, Gary A. Brook, Fraser Buchanan, Aurélie Carlier, Saray Chen, Evan Claes, Smadar Cohen, John Connelly, Matthew J. Dalby, Paul D. Dalton, Jonathan I. Dawson, Jan de Boer, Tim Desmet, Hannah Donnelly, Filip Donvil, Jenna L. Dziki, Dominik Egger, Miriam Filippi, Marius Gensler, David Gibbs, Susan Gibbs, Rosalind Hannen, Jan Hansmann, Alan R. Harvey, Tommy Heck, Marietta Herrmann, Andrew L. Hook, Jeffrey A. Hubbell, Dietmar W. Hutmacher, Clara Grace Hynes, Johan Joly, Adam M. Jorgensen, Janos Kanczler, Marcel Karperien, Cornelia Kasper, Candace L. Kerr, Kristopher A. Kilian, Sebastian Kreß, Vanessa LaPointe, Matthias W. Laschke, Anders Lindahl, Ricardo Londono, Frank P. Luyten, Marina Marechal, Mikaël M. Martino, Malcolm Moos, Lorenzo Moroni, Emily Morra, Simon Myers, Sabrina Nebel, Minghao Nie, David R. Nisbet, Kelly L. O'Neill, Nkemcho Ojeh, Richard OC. Oreffo, Martin Oudega, Robert Passier, Ana Paula Pêgo, Mark F. Pittenger, Giles W. Plant, Jeffrey J. Rice, Bernard A.J. Roelen, Anaïs Schaschkow, Arnaud Scherberich, Jan Schrooten, Evan A. Scott, Brian M. Sicari, Maarten Sonnaert, Thomas Später, Shoji Takeuchi, Biranche Tandon, Rahul Tare, Roman Truckenmüller, Monica Tsimbouri, Jorge Alfredo Uquillas, Dieter Van Assche, Steven Vermeulen, Sophie Verrier, Pamela Walsh, David A. Winkler
Publikováno v: Tissue Engineering ISBN: 9780128244593
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b428686cabf006087fc936a5d12d8d57
https://doi.org/10.1016/b978-0-12-824459-3.01002-7
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9
Distinct patterns of spasticity and corticospinal connectivity following complete spinal cord injury
Autor: Steven Kirshblum, Martin Oudega, Monica A. Perez, James D. Guest, Sina Sangari
Publikováno v: J Physiol
Key points Damage to corticospinal axons have implications for the development of spasticity following spinal cord injury (SCI). Here, we examined to which extent residual corticospinal connections and spasticity are present in muscles below the inju
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fdce1dfcb56d65b53d2ae8f2f57ff7
https://doi.org/10.1113/jp281862
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10
Paired corticospinal-motoneuronal stimulation and exercise after spinal cord injury
Autor: Martin Oudega, Monica A. Perez, Hang Jin Jo, Michael S.A. Richardson
Publikováno v: The journal of spinal cord medicine. 44(sup1)
CONTEXT Rehabilitation after spinal cord injury (SCI) relies on the use of exercise training, which has limited functional gains. There is a need to develop more efficient approaches to facilitate recovery after SCI. METHODS This review focuses on a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c398326df1936618ba4c75e75cb766f7
https://pubmed.ncbi.nlm.nih.gov/34779722
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