Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Martin Filipits"'
Autor:
Viktoria Knöbl, Lukas Maier, Stefan Grasl, Carmen Kratzer, Felix Winkler, Vanessa Eder, Hubert Hayden, Maria Amparo Sahagun Cortez, Monika Sachet, Rudolf Oehler, Sophie Frantal, Christian Fesl, Karin Zehetner, Georg Pfeiler, Rupert Bartsch, Florian Fitzal, Christian F. Singer, Martin Filipits, Michael Gnant, Christine Brostjan
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Monocytes comprise subsets of classical, intermediate and non-classical monocytes with distinct anti- or pro-tumor effects in breast cancer (BC). They are modulated by estrogen, and can contribute to BC control by endocrine therap
Externí odkaz:
https://doaj.org/article/67d59ab9099a49d8987574d7fbdf4ebb
Autor:
Kerstin Wimmer, Monika Sachet, Cristiano Ramos, Sophie Frantal, Hanna Birnleitner, Christine Brostjan, Ruth Exner, Martin Filipits, Zsuzsanna Bago-Horvath, Margaretha Rudas, Rupert Bartsch, Michael Gnant, Christian F. Singer, Marija Balic, Daniel Egle, Rudolf Oehler, Florian Fitzal
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Background Epirubicin/cyclophosphamide (EC) and docetaxel (D) are commonly used in a sequential regimen in the neoadjuvant treatment of early, high-risk or locally advanced breast cancer (BC). Novel approaches to increase the response rate c
Externí odkaz:
https://doaj.org/article/472702d7c4da4a55985a14b3016a1c91
Autor:
Klaus Hackner, Anna Buder, Maximilian J Hochmair, Matthaeus Strieder, Christina Grech, Hannah Fabikan, Otto C. Burghuber, Peter Errhalt, Martin Filipits
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 15 (2021)
Background: Proof of the T790M resistance mutation is mandatory if patients with EGFR -mutated non-small cell lung cancer (NSCLC) progress under first- or second-generation tyrosine kinase inhibitor therapy. In addition to rebiopsy, analysis of plasm
Externí odkaz:
https://doaj.org/article/b8a7594e6de848eeacd5b8e890ad5a50
Autor:
Christian F. Singer, Frederik Holst, Stefan Steurer, Eike Burandt, Sigurd Lax, Raimund Jakesz, Margaretha Rudas, Herbert Stöger, Richard Greil, Guido Sauter, Martin Filipits, Ronald Simon, Michael Gnant
Publikováno v:
Cancer Research. 83:P2-11
Purpose: Estrogen receptor (ER) expression predicts response to endocrine therapy and is a prognostic biomarker. However, no ER-associated biomarker is able to identify patients with particularly favorable outcome among ER+ tumors. We investigated th
Autor:
Carsten Denkert, Miguel Martín, Michael Untch, Hervé R. Bonnefoi, Erik S. Knudsen, Seock-Ah Im, Angela DeMichele, Agnieszka Witkiewicz, Laura Van ’t Veer, Sung-Bae Kim, Harry D. Bear, Nicole McCarthy, Karen Gelmon, Frederik Marmé, José Ángel García-Sáenz, Nicholas Turner, Federico Rojo, Martin Filipits, Lesley-Ann Martin, Peter A. Fasching, Christian Schem, Catherine M. Kelly, Toralf Reimer, Masakazu Toi, Hope Rugo, Michael Gnant, Andreas Makris, Yuan Liu, Karsten Weber, Sivaramakrishna Rachakonda, Sibylle Loibl
Publikováno v:
Cancer Research. 83:HER2-06
Background: Breast cancer with low HER2 expression (HER2-low) is of high clinical relevance because of new therapeutic options with antibody-drug conjugates. We have recently shown in a large cohort from neoadjuvant clinical trials that HER2-low brea
Autor:
Martin Filipits, Eva Maria Jäger, Anna Glechner, Elisabeth Zwickl-Traxler, Gabriele Schmoranzer, Martin Pecherstorfer, Gudrun Kreye
Publikováno v:
ESMO Open, Vol 5, Iss 5 (2020)
Background Patients with metastatic breast cancer (MBC) have a considerable symptom burden and may require extensive care for a long period of time. Palliative care (PC) has the potential to improve their quality of care and reduce their use of medic
Externí odkaz:
https://doaj.org/article/599c7c02ae694d1f8787295d9226afe1
Autor:
Christian F, Singer, Frederik, Holst, Stefan, Steurer, Eike C, Burandt, Sigurd F, Lax, Raimund, Jakesz, Margaretha, Rudas, Herbert, Stöger, Richard, Greil, Guido, Sauter, Martin, Filipits, Ronald, Simon, Michael, Gnant
Publikováno v:
Clinical Cancer Research. 28:4112-4120
Purpose: Estrogen receptor (ER) expression is a prognostic parameter in breast cancer, and a prerequisite for the use of endocrine therapy. In ER+ early breast cancer, however, no receptor-associated biomarker exists that identifies patients with a p
Autor:
Robert Pirker, Martin Filipits
Publikováno v:
ESMO Open, Vol 4, Iss 5 (2019)
Externí odkaz:
https://doaj.org/article/184fd5521fe049b7971db76d04cc140f
Autor:
Group, Martin Filipits, Verena Kainz, Viktor Sebek, Herwig Zach, on behalf of the Liquid Biopsy Collaborative Study Group on behalf of the Liquid Biopsy Collaborative Study
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3528
Background: The detection of the EGFR T790M (T790M) mutation in non-small cell lung cancer (NSCLC) patients who progressed under treatment with first- or second-generation EGFR-tyrosine kinase inhibitors (TKIs) is important to offer a subsequent ther
Autor:
Anna Buder, Ellen Heitzer, Julie Waldispühl-Geigl, Sabrina Weber, Tina Moser, Maximilian J. Hochmair, Klaus Hackner, Peter Errhalt, Ulrike Setinek, Martin Filipits
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 618 (2021)
Background: To assess the clinical relevance of genome-wide somatic copy-number alterations (SCNAs) in plasma circulating tumor DNA (ctDNA) from advanced epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma patients. Methods: We includ
Externí odkaz:
https://doaj.org/article/3e8f9f1125e24cf695bf8860e871d55e