Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Martin, Wohlwend"'
Autor:
Jeremy Vidal, Eric A. Fernandez, Martin Wohlwend, Pirkka‐Pekka Laurila, Andrea Lopez‐Mejia, Julien Ochala, Alexander J. Lobrinus, Bengt Kayser, Isabel C. Lopez‐Mejia, Nicolas Place, Nadège Zanou
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 6, Pp 2882-2897 (2023)
Abstract Background Decreased ryanodine receptor type 1 (RyR1) protein levels are a well‐described feature of recessive RYR1‐related myopathies. The aim of the present study was twofold: (1) to determine whether RyR1 content is also decreased in
Externí odkaz:
https://doaj.org/article/743ce0bab667448485a705bb78576a40
Autor:
Martin Wohlwend, Pirkka-Pekka Laurila, Ludger JE Goeminne, Tanes Imamura de lima, Ioanna Daskalaki, Xiaoxu Li, Giacomo von Alvensleben, Barbara Crisol, Renata Mangione, Hector Gallart-Ayala, Amelia Lalou, Olivier Burri, Stephen Butler, Jonathan C Morris, Nigel Turner, Julijana Ivanisevic, Johan Auwerx
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/c54b2c68b1ee4416b63703caea4ade82
Autor:
Martin Wohlwend, Pirkka-Pekka Laurila, Ludger JE Goeminne, Tanes Lima, Ioanna Daskalaki, Xiaoxu Li, Giacomo von Alvensleben, Barbara Crisol, Renata Mangione, Hector Gallart-Ayala, Amélia Lalou, Olivier Burri, Stephen Butler, Jonathan Morris, Nigel Turner, Julijana Ivanisevic, Johan Auwerx
Publikováno v:
eLife, Vol 12 (2024)
Age-related muscle wasting and dysfunction render the elderly population vulnerable and incapacitated, while underlying mechanisms are poorly understood. Here, we implicate the CERS1 enzyme of the de novo sphingolipid synthesis pathway in the pathoge
Externí odkaz:
https://doaj.org/article/d20d88bab189434da372a5ca93b464e3
Autor:
Jonas R Knudsen, Kaspar W Persson, Carlos Henriquez-Olguin, Zhencheng Li, Nicolas Di Leo, Sofie A Hesselager, Steffen H Raun, Janne R Hingst, Raphaël Trouillon, Martin Wohlwend, Jørgen FP Wojtaszewski, Martin AM Gijs, Thomas Elbenhardt Jensen
Publikováno v:
eLife, Vol 12 (2023)
Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and insulin resistance is unclear. Here, we used fixed and live-cell imaging to study microtubule-
Externí odkaz:
https://doaj.org/article/c8529b07c7914a5394f32d161d299fea
Autor:
Kristine Williams, Lars R. Ingerslev, Jette Bork-Jensen, Martin Wohlwend, Ann Normann Hansen, Lewin Small, Rasmus Ribel-Madsen, Arne Astrup, Oluf Pedersen, Johan Auwerx, Christopher T. Workman, Niels Grarup, Torben Hansen, Romain Barrès
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Obesity and type 2 diabetes (T2D) are metabolic disorders characterized by insulin resistance in skeletal muscle. Here, the authors map skeletal muscle enhancer elements dynamically regulated after exposure to free fatty acid palmitate or inflammator
Externí odkaz:
https://doaj.org/article/6a8adde43f8e4a568fb7abbf52f498c8
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background Exercise of patients with intermittent claudication improves walking performance. Exercise does not usually increase blood flow, but seems to increase muscle mitochondrial enzyme activities. Although exercise is beneficial in most
Externí odkaz:
https://doaj.org/article/39b668e0344a4d6291439f5a0cf3e655
Autor:
Jonas R Knudsen, Kaspar W Persson, Carlos Henriquez-Olguin, Zhencheng Li, Nicolas Di Leo, Sofie A Hesselager, Steffen H Raun, Janne R Hingst, Raphaël Trouillon, Martin Wohlwend, Jørgen FP Wojtaszewski, Martin AM Gijs, Thomas Elbenhardt Jensen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a367e84bb88270e456f5bea7bfe1aa3e
https://doi.org/10.7554/elife.83338.sa2
https://doi.org/10.7554/elife.83338.sa2
Autor:
Jeremy Vidal, Eric Fernandez, Martin Wohlwend, Pirkka-Pekka Laurila, Andrea Lopez Mejia, Julien Ochala, Isabel Christina Lopez Mejia, Johannes Alexandre Lobrinus, Bengt Kayser, Nicolas Place, Nadège Zanou
Decreased ryanodine receptor type 1 (RyR1) protein is a hallmark of recessiveRYR1-related myopathies (RyR1-RM), which are caused by recessive mutations in theRYR1gene. It is not clear how the decrease in the RyR1 protein triggers muscular disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::925ef817ae4eb1e539442ceadc0c3884
https://doi.org/10.1101/2023.02.01.23285343
https://doi.org/10.1101/2023.02.01.23285343
Autor:
Jonas R. Knudsen, Kaspar W. Persson, Carlos Henriquez-Olguin, Zhencheng Li, Nicolas Di Leo, Steffen H. Raun, Janne R. Hingst, Raphaël Trouillon, Martin Wohlwend, Jørgen F. P. Wojtaszewski, Martin A. M. Gijs, Thomas E. Jensen
Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and insulin resistance is unclear. Here, we used fixed and live-cell imaging to study microtubule-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776449b398637e1feaba3ffbac672209
https://doi.org/10.1101/2022.09.19.508621
https://doi.org/10.1101/2022.09.19.508621
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165038 (2016)
Mitochondria are essential for energy production in the muscle cell and for this they are dependent upon a sufficient supply of oxygen by the circulation. Exercise training has shown to be a potent stimulus for physiological adaptations and mitochond
Externí odkaz:
https://doaj.org/article/e493e25264a04bdfbdc6d11e302d3ad6