Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Martin, Wasser"'
Autor:
Tira J. Tan, W. X. Gladys Ang, Who-Whong Wang, Hui-Shan Chong, Sze Huey Tan, Rachael Cheong, John Whay-Kuang Chia, Nicholas L. Syn, Wai Ho Shuen, Rebecca Ba, Nivashini Kaliaperumal, Bijin Au, Richard Hopkins, Xinhua Li, Aaron C. Tan, Amanda O. L. Seet, John E. Connolly, Thaschawee Arkachaisri, Valerie Chew, Ahmad bin Mohamed Lajam, Dianyan Guo, Marvin Z. W. Chew, Martin Wasser, Pavanish Kumar, Salvatore Albani, Han Chong Toh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Ad-sig-hMUC1/ecdCD40L is a recombinant adenovirus vaccine comprising human MUC1 antigen fused to the extracellular domain of the CD40 ligand. Here the authors report the result of a phase I clinical trial of Ad-sig-hMUC1/ecdCD40L in patients with adv
Externí odkaz:
https://doaj.org/article/bc9966f3f06642699fbd9cc02be4f7e3
Autor:
Marie J. Y. Reolo, Masayuki Otsuka, Justine Jia Wen Seow, Joycelyn Lee, Yun Hua Lee, Phuong H. D. Nguyen, Chun Jye Lim, Martin Wasser, Camillus Chua, Tony K. H. Lim, Wei Qiang Leow, Alexander Chung, Brian K. P. Goh, Pierce K. H. Chow, Ramanuj DasGupta, Joe Poh Sheng Yeong, Valerie Chew
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionDespite recent advances in immunotherapy for hepatocellular carcinoma (HCC), the overall modest response rate underscores the need for a better understanding of the tumor microenvironment (TME) of HCC. We have previously shown that CD38 i
Externí odkaz:
https://doaj.org/article/5a4cd342a33d48c3a5625cfed3c9b0ef
Autor:
Phuong H. D. Nguyen, Martin Wasser, Chong Teik Tan, Chun Jye Lim, Hannah L. H. Lai, Justine Jia Wen Seow, Ramanuj DasGupta, Cheryl Z. J. Phua, Siming Ma, Jicheng Yang, Sheena D/O Suthen, Wai Leong Tam, Tony K. H. Lim, Joe Yeong, Wei Qiang Leow, Yin Huei Pang, Gwyneth Soon, Tracy Jiezhen Loh, Wei Keat Wan, Chung Yip Chan, Peng Chung Cheow, Han Chong Toh, Alfred Kow, Yock Young Dan, Juinn Huar Kam, Shridhar Iyer, Krishnakumar Madhavan, Alexander Chung, Glenn K. Bonney, Brian K. P. Goh, Naiyang Fu, Victor C. Yu, Weiwei Zhai, Salvatore Albani, Pierce K. H. Chow, Valerie Chew
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
In order to design cancer immune therapies, it is important to understand how tumours evade the immune response that is mounted against them. Authors here analyse the distribution and properties of immune cells in hepatocellular carcinoma and describ
Externí odkaz:
https://doaj.org/article/2648047cd2d74e93ad29e2f0557f8fa3
Autor:
Phuong H. D. Nguyen, Siming Ma, Cheryl Z. J. Phua, Neslihan A. Kaya, Hannah L. H. Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony K. H. Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred W. C. Kow, Yock Young Dan, Alexander Chung, Brian K. P. Goh, Salvatore Albani, Pierce K. H. Chow, Weiwei Zhai, Valerie Chew
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Intratumoural heterogeneity is a feature of liver cancer. Here, the authors demonstrate that heterogeneity exists at the immune cell level in liver cancer and show that tumours with high intratumoural immune heterogeneity demonstrated an immune suppr
Externí odkaz:
https://doaj.org/article/04bfa3244f6242d895349149a2c716b4
Autor:
Joo Guan Yeo, Jing Yao Leong, Shi Huan Tay, Karen Donceras Nadua, Danielle E. Anderson, Amanda Jin Mei Lim, Xiang Wen Ng, Su Li Poh, Dianyan Guo, Katherine Nay Yaung, Pavanish Kumar, Martin Wasser, Sharifah Nur Hazirah, Nursyuhadah Sutamam, Camillus Jian Hui Chua, Martin Qui, Randy Foo, Akshamal Mihiranga Gamage, Kee Thai Yeo, Lakshmi Ramakrishna, Thaschawee Arkachaisri, Barnaby E. Young, David Chien Lye, Lin-Fa Wang, Chia Yin Chong, Natalie Woon Hui Tan, Jiahui Li, Kai-Qian Kam, Florent Ginhoux, Koh Cheng Thoon, Jerry Kok Yen Chan, Chee Fu Yung, Salvatore Albani
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
An accurate depiction of the convalescent COVID-19 immunome will help delineate the immunological milieu crucial for disease resolution and protection. Using mass cytometry, we characterized the immune architecture in patients recovering from mild CO
Externí odkaz:
https://doaj.org/article/4b92e1494b784bdea9f64c9ceb274c61
Autor:
Katherine Nay Yaung, Joo Guan Yeo, Pavanish Kumar, Martin Wasser, Marvin Chew, Angelo Ravelli, Annie Hui Nee Law, Thaschawee Arkachaisri, Alberto Martini, David S Pisetsky, Salvatore Albani
Publikováno v:
The Lancet Rheumatology. 5:e151-e165
Autor:
Chun Jye Lim, Phuong Hoang Diem Nguyen, Martin Wasser, Pavanish Kumar, Yun Hua Lee, Nurul Jannah Mohamed Nasir, Camillus Chua, Liyun Lai, Sharifah Nur Hazirah, Josh Jie Hua Loh, Li Yan Khor, Joe Yeong, Tony Kiat Hon Lim, Alvin Wei Xiang Low, Salvatore Albani, Tsung Wen Chong, Valerie Chew
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Intravesical Bacillus Calmette-Guerin (BCG) is an effective immunotherapy for non-muscle invasive bladder cancer (NMIBC). However, recurrence and progression remain frequent warranting deeper insights into its mechanism. We herein comprehensively pro
Externí odkaz:
https://doaj.org/article/d5434b2cea8f4fb39dce053aefa2e177
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background Many human muscle wasting diseases are associated with abnormal nuclear localization. During metamorphosis in Drosophila melanogaster, multi-nucleated larval dorsal abdominal muscles either undergo cell death or are remodeled to t
Externí odkaz:
https://doaj.org/article/0e995de241d84c71b051648b703a5284
Publikováno v:
Biology Open, Vol 6, Iss 3, Pp 390-401 (2017)
Time-lapse microscopy is a powerful tool to investigate cellular and developmental dynamics. In Drosophila melanogaster, it can be used to study division cycles in embryogenesis. To obtain quantitative information from 3D time-lapse data and track pr
Externí odkaz:
https://doaj.org/article/85249c1844fa46faa60510993cb22310
Autor:
Phuong H. D. Nguyen, Siming Ma, Cheryl Z. J. Phua, Neslihan A. Kaya, Hannah L. H. Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony K. H. Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred W. C. Kow, Yock Young Dan, Alexander Chung, Glen K. Bonney, Brian K. P. Goh, Salvatore Albani, Pierce K. H. Chow, Weiwei Zhai, Valerie Chew
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21556-y.
Externí odkaz:
https://doaj.org/article/08ad460145fc4cdeaa1c1a80cb3d6247