Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Martin, Vokurka"'
Autor:
Maryam Golshani, Ludmila Maffei Svobodová, Lubomír Štěpánek, Jan Zeman, Petra Nytrová, Helena Posová, Petra Petrásková, Olga Novotná, Michaela Nováková, Viktor Černý, Jiří Beneš, Libuše Kolářová, Martin Vokurka, Jiří Hrdý
Publikováno v:
Vaccines, Vol 10, Iss 12, p 2038 (2022)
Background: COVID-19 pandemic has led to a loss of human life in millions and devastating socio-economic consequences worldwide. So far, vaccination is the most effective long-term strategy to control and prevent severe COVID-19 disease. The aim of t
Externí odkaz:
https://doaj.org/article/6a6b6ff52f59481797d91f4a759fb8f1
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215028 (2019)
Expression of hepcidin, the hormone regulating iron homeostasis, is increased by iron overload and decreased by accelerated erythropoiesis or iron deficiency. The purpose of the study was to examine the effect of these stimuli, either alone or in com
Externí odkaz:
https://doaj.org/article/41d652ffd7c84526973f3968bbdb36df
Autor:
Erik Vlcak, Jana Šáchová, Jiří Novotný, Jan Brábek, Petr Přikryl, Daniel Rösel, Miluše Hradilová, Lucie Pfeiferová, Barbora Dvořánková, Jana Frýdlová, Martin Vokurka, Lukáš Lacina, Michal Kolář, Karolína Strnadová, Karel Smetana, Jana Šmigová
Publikováno v:
Histochemistry and Cell Biology. 157:153-172
The incidence of cutaneous malignant melanoma is increasing worldwide. While the treatment of initial stages of the disease is simple, the advanced disease frequently remains fatal despite novel therapeutic options . This requires identification of n
Autor:
Jana Frýdlová, Zuzana Rychtarčíková, Iuliia Gurieva, Martin Vokurka, Jaroslav Truksa, Jan Krijt
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186844 (2017)
Tmprss6-mutated mask mice display iron deficiency anemia and high expression of hepcidin. The aim of the study was to determine the effect of erythropoietin administration on proteins participating in the control of iron homeostasis in the liver and
Externí odkaz:
https://doaj.org/article/cdea54ec9fe14973bd0c5ad5b4418b04
Autor:
Tereza Brogyányi, Robert Kaplánek, Zdeněk Kejík, Božena Hosnedlová, Veronika Antonyová, Nikita Abramenko, Kateřina Veselá, Pavel Martásek, Martin Vokurka, Des R. Richardson, Milan Jakubek
Publikováno v:
Biomedicine & Pharmacotherapy 155(November), nestránkováno. (2022)
Dysregulation of iron homeostasis is one of the important processes in the development of many oncological diseases, such as pancreatic cancer. Targeting it with specific agents, such as an iron chelator, are promising therapeutic methods. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fa94e4bc20c9bafa41d0c7aab14153
Autor:
Betty Berezovsky, Jana Frýdlová, Iuliia Gurieva, Daniel W. Rogalsky, Martin Vokurka, Jan Krijt
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 5899
The purpose of the study was to investigate the expression of ferroportin protein following treatments that affect systemic hepcidin. Administration of erythropoietin to C57BL/6J mice decreased systemic hepcidin expression; it also increased heart fe
Publikováno v:
Medsoft 2021. 33:8-10
Příspěvek shrnuje zkušenosti s online výukou patologické fy - ziologie i jejími dopady na úroveň znalostí studentů, nároky na organizaci, zaškolení učitelů a využití různých formátů pro tvor- bu a realizaci online výuky. Nazna
Autor:
Jana Frýdlová, Petr Přikryl, Jaroslav Truksa, Lucas L Falke, Xin Du, Iuliia Gurieva, Martin Vokurka, Jan Krijt
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148540 (2016)
Matriptase-2 (TMPRSS6) is an important negative regulator of hepcidin expression; however, the effects of iron overload or accelerated erythropoiesis on liver TMPRSS6 protein content in vivo are largely unknown. We determined TMPRSS6 protein content
Externí odkaz:
https://doaj.org/article/565129c3e11a464893851c46bafd3f6d
Publikováno v:
Medsoft 2020. 32:47-54
S využitím námi vyvinutého vývojového nástroje BodyLight.js byla vytvořena výuková simulační aplikace, která interaktivní formou vysvětluje metabolismus železa v lidském organismu. V pozadí aplikace je matematický model vytvořený