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of 10
pro vyhledávání: '"Martin, Vo"'
Autor:
Anda Stan, Korey Bosart, Mehak Kaur, Martin Vo, Wilber Escorcia, Ryan J Yoder, Renee A Bouley, Ruben C Petreaca
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0299114 (2024)
Analyzed endometrial cancer (EC) genomes have allowed for the identification of molecular signatures, which enable the classification, and sometimes prognostication, of these cancers. Artificial intelligence algorithms have facilitated the partitioni
Externí odkaz:
https://doaj.org/article/a4a18f88152c45d390984926a9ef0412
Autor:
Meghan Graber, Hayley Barta, Ryan Wood, Amrit Pappula, Martin Vo, Ruben C. Petreaca, Wilber Escorcia
Publikováno v:
Biology, Vol 10, Iss 8, p 714 (2021)
DGAT2 is a transmembrane protein encoded by the DGAT2 gene that functions in lipid metabolism, triacylglycerol synthesis, and lipid droplet regulation. Cancer cells exhibit altered lipid metabolism and mutations in DGAT2 may contribute to this state.
Externí odkaz:
https://doaj.org/article/033fe6c62d664faf8811ed86006797b3
Autor:
Martin, Vo, Lance, Kuo-Esser, Mauricio, Dominguez, Hayley, Barta, Meghan, Graber, Alex, Rausenberger, Ryan, Miller, Nathan, Sommer, Wilber, Escorcia
Cell metrics such as area, length, and width provide informative data about cell cycle dynamics. Factors that affect these dimensions include environmental conditions and genotypic differences. Fission yeast (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3ba2681992e2601efd3129a3c80182
Autor:
Ruben C Petreaca, Ryan Wood, Amrit L. Pappula, Martin Vo, Wilber Escorcia, Meghan Graber, Hayley Barta
Publikováno v:
Biology
Biology, Vol 10, Iss 714, p 714 (2021)
Volume 10
Issue 8
Biology, Vol 10, Iss 714, p 714 (2021)
Volume 10
Issue 8
Simple Summary Cellular metabolism including lipid metabolism is often altered in cancer cells. To keep up with the high energetic demand of cancer cells lipid metabolism is increased. Thus, mutations, changes in gene expression or other alterations
Publikováno v:
Cancer Research. 73:2794-2794
Current strategies for developing new anticancer drugs rely heavily on preclinical testing in cancer cell lines and their derived in vivo cell line xenograft models. The value of a predictive assay is heavily dependent on the extent to which it can r
Autor:
Steve Hoffmaster, Kesavan Nair Praveen, Bhavya Murali, Cyrus Mirsaidi, Kenna Anderes, Thomas Broudy, Tatiana Ruiz-Larroya, Martin Vo, Nicole Streiner
Publikováno v:
Cancer Research. 72:881-881
Combination therapy, with rare exception, is a requirement for successfully treating cancer patients. Advances in genetic characterization coupled with a growing understanding of tumor heterogeneity are poised to revolutionize future strategies for c
Autor:
Kenna Anderes, Koichi Yokota, Nicole Streiner, Kesavan Nair Praveen, Martin Vo, Takeshi Ikeya
Publikováno v:
Cancer Research. 72:5270-5270
Tumor cell microenvironment has significant impact on growth kinetics, cell signaling and response to drug treatments. 3D models are more biologically relevant models compared to 2D models and have gained preference among researchers and drug develop
Autor:
Kesavan Praveen Nair, Steve Hoffmaster, Cyrus Mirsaidi, Kenna Anderes, Erica I. Livingston, Megan Laurance, Sandeep Sanga, Thomas Broudy, Martin Vo
Publikováno v:
Cancer Research. 72:3611-3611
Chemotherapy has a well-established history of checkered success for treatment in a number of solid and hematological malignancies alike. Numerous reports have demonstrated heightened levels of response to some of these agents within subpopulations o
Autor:
Patrick M. O'Connor, Steve Hoffmaster, Thomas Broudy, Kenna Anderes, Kesavan Praveen Nair, Martin Vo, Cyrus Mirsaidi, Nicole Streiner
Publikováno v:
Molecular Cancer Therapeutics. 10:B123-B123
The purpose of this study is to investigate whether the chemosensitivity of patient-derived primary tumor tissue when coupled with molecular characterization provides a stronger correlation to clinical outcomes than conventional preclinical anticance
Autor:
Martin VO; School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, United Nations Rd., Dar Es Salaam 11103, Tanzania., Tesha NA; School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, United Nations Rd., Dar Es Salaam 11103, Tanzania., Sunguya BF; School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, United Nations Rd., Dar Es Salaam 11103, Tanzania.
Publikováno v:
Viruses [Viruses] 2023 Oct 20; Vol. 15 (10). Date of Electronic Publication: 2023 Oct 20.