Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Martin, Schlitzer"'
Autor:
Marc Kaethner, Georg Rennar, Tom Gallinger, Tobias Kämpfer, Andrew Hemphill, Patrick Mäder, Ana Luque-Gómez, Martin Schlitzer, Britta Lundström-Stadelmann
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 8, Iss 12, p 517 (2023)
The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the severe zoonotic disease alveolar echinococcosis. New treatment options are urgently needed. Disulfiram and dithiocarbamates were previously shown to exhibit activity aga
Externí odkaz:
https://doaj.org/article/a20891c0f6bc47f3831ea5e45a151b6e
Autor:
Tom L. Gallinger, Samuel Y. Aboagye, Wiebke Obermann, Michael Weiss, Arnold Grünweller, Carlo Unverzagt, David L. Williams, Martin Schlitzer, Simone Haeberlein
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 119 (2022)
Schistosomiasis is a neglected tropical disease caused by blood flukes of the genus Schistosoma. In silico screenings of compounds for the identification of novel anti-parasitic drug candidates have received considerable attention in recent years, in
Externí odkaz:
https://doaj.org/article/29a5cf11c1a04b6bbf5a32fd2c925484
Autor:
Martin Schlitzer, Susanne Michels, Rolf Erik Emmerich, Carsten Culmsee, Anna Lena Pfaff, Lukas Hinder
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 378:184-196
Ferroptosis is a form of oxidative cell death that is increasingly recognized as a key mechanism not only in neurodegeneration but also in regulated cell death, causing disease in other tissues. In neurons, major hallmarks of ferroptosis involve the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b534780907915972124e52ad65f32b
https://doi.org/10.1124/jpet.121.000534
https://doi.org/10.1124/jpet.121.000534
Autor:
Mandy Beutler, Julie Harnischfeger, Michael H.W. Weber, Steffen R. Hahnel, Thomas Quack, Ariane Blohm, Monique E. Ueberall, Thomas Timm, Günter Lochnit, Georg A. Rennar, Tom L. Gallinger, Hicham Houhou, Stefan Rahlfs, Franco H. Falcone, Katja Becker, Martin Schlitzer, Simone Haeberlein, Peter Czermak, Denise Salzig, Christoph G. Grevelding
Publikováno v:
European Journal of Medicinal Chemistry. 251:115179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c73f32d77e20562429eadbbb40b979f1
https://doi.org/10.1016/j.ejmech.2023.115179
https://doi.org/10.1016/j.ejmech.2023.115179
Autor:
Georg A. Rennar, Tom L. Gallinger, Patrick Mäder, Kerstin Lange-Grünweller, Simone Haeberlein, Arnold Grünweller, Christoph G. Grevelding, Martin Schlitzer
Publikováno v:
European journal of medicinal chemistry. 242
Schistosomiasis is a neglected tropical disease with more than 200 million new infections per year. It is caused by parasites of the genus Schistosoma and can lead to death if left untreated. Currently, only two drugs are available to combat schistos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45d7c8d1a31c9fd252023f67a107243
https://pubmed.ncbi.nlm.nih.gov/36027862
https://pubmed.ncbi.nlm.nih.gov/36027862
Autor:
Tom L. Gallinger, Wiebke Obermann, Kerstin Lange‐Grünweller, Nina Schmidt, Simone Haeberlein, Arnold Grünweller, Christoph G. Grevelding, Martin Schlitzer
Publikováno v:
Archiv der Pharmazie. 356:2200491
Schistosomiasis or bilharzia is caused by blood flukes of the genus Schistosoma and represents a considerable health and economic burden in tropical and subtropical regions. The treatment of this infectious disease relies on one single drug: praziqua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67980eb4935ee81c9dffceb1226ac0bd
https://doi.org/10.1002/ardp.202200491
https://doi.org/10.1002/ardp.202200491
Autor:
Martin Schlitzer, Alejandra M. Peter Ventura, Simone Haeberlein, Arnold Grünweller, Kerstin Lange-Grünweller, Roland K. Hartmann, Christoph G. Grevelding
Publikováno v:
Chemmedchem
The parasitic disease schistosomiasis is the cause of more than 200 000 human deaths per year. Although the disease is treatable, there is one major shortcoming: praziquantel has been the only drug used to combat these parasites since 1977. The risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a4aa722b2aca538e01d971bd0463c0
https://doi.org/10.1002/cmdc.201900423
https://doi.org/10.1002/cmdc.201900423
Autor:
Martin Schlitzer, David H. Drewry, Christoph G. Grevelding, Reimar Krieg, Patrick Mäder, Nelly El-Sakkary, Jonathan L. Vennerstrom, Katja Becker, Conor R. Caffrey
Publikováno v:
Neglected Tropical Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c771c08ddc7d76b47fa598bc2a78a0
https://doi.org/10.1002/9783527808656.ch8
https://doi.org/10.1002/9783527808656.ch8
Autor:
Isabell Schencking, Roland K. Hartmann, Rolf Erik Emmerich, Wibke E. Diederich, Torsten Steinmetzer, Martin Schlitzer, Eva Maria Schäfer, J H William Scanlan, Benjamin M Wenzel
Publikováno v:
Antimicrob Agents Chemother
RNase P is an essential enzyme responsible for tRNA 5′-end maturation. In most bacteria, the enzyme is a ribonucleoprotein consisting of a catalytic RNA subunit and a small protein cofactor termed RnpA. Several studies have reported small-molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62157dcf268c1025f587fc467010624
https://pubmed.ncbi.nlm.nih.gov/33972249
https://pubmed.ncbi.nlm.nih.gov/33972249
Autor:
Christoph G. Grevelding, Georg Alexander Rennar, Alejandra M. Peter Ventura, Patrick Mäder, Martin Schlitzer
Publikováno v:
ChemMedChem. 13:2374-2389
Chemotherapy based on repeated doses of praziquantel remains the most effective control strategy against schistosomiasis, a neglected tropical disease caused by platyhelminths of the genus Schistosoma spp. Its long-term use, however, raises serious c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06515e6e06902a636fa7ec4711bf8ac2
https://doi.org/10.1002/cmdc.201800572
https://doi.org/10.1002/cmdc.201800572