Zobrazeno 1 - 10
of 537
pro vyhledávání: '"Martin, Schaller"'
Autor:
Nicolas Joly-Tonetti, Raphael Legouffe, Aurore Tomezyk, Clémence Gumez, Mathieu Gaudin, David Bonnel, Martin Schaller
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 6, Pp 1281-1290 (2024)
Abstract Introduction Amorolfine 5% lacquer is an established topical treatment for fungal infection of the nails. The success of topical therapy for onychomycosis depends on whether the permeated drug concentration in the deep nail bed is retained a
Externí odkaz:
https://doaj.org/article/22f496657ce4414c826ad0828f950ae6
Autor:
Nicolas Joly-Tonetti, Raphael Legouffe, Aurore Tomezyk, Clémence Gumez, Mathieu Gaudin, David Bonnel, Martin Schaller
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 6, Pp 1269-1279 (2024)
Abstract Introduction Onychomycosis is a fungal infection of the nails that can be challenging to treat. Here, matrix-assisted laser desorption ionization–Fourier transform ion cyclotron resonance (MALDI-FTICR) imaging was applied to the quantitati
Externí odkaz:
https://doaj.org/article/017a068c282947998a65a2f42184fd9d
Autor:
Francisco Meraz-Torres, Heike Niessner, Sarah Plöger, Simon Riel, Barbara Schörg, Nicolas Casadei, Manfred Kneilling, Martin Schaller, Lukas Flatz, Boris Macek, Thomas Eigentler, Olaf Rieß, Claus Garbe, Teresa Amaral, Tobias Sinnberg
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background MEK inhibitors (MEKi) were shown to be clinically insufficiently effective in patients suffering from BRAF wild-type (BRAF WT) melanoma, even if the MAPK pathway was constitutively activated due to mutations in NRAS or NF-1. Thus,
Externí odkaz:
https://doaj.org/article/35307e889f494a0d91d148dbfa645149
Autor:
Christian Beck, Janes Krusche, Anna Notaro, Axel Walter, Lara Kränkel, Anneli Vollert, Regine Stemmler, Johannes Wittmann, Martin Schaller, Christoph Slavetinsky, Christoph Mayer, Cristina De Castro, Andreas Peschel
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTThe species- and clone-specific susceptibility of Staphylococcus cells for bacteriophages is governed by the structures and glycosylation patterns of wall teichoic acid (WTA) glycopolymers. The glycosylation-dependent phage-WTA interactions i
Externí odkaz:
https://doaj.org/article/00260f1e15e944578a9349b13820b6cd
Autor:
Philipp Knopf, Dimitri Stowbur, Sabrina H. L. Hoffmann, Natalie Hermann, Andreas Maurer, Valentina Bucher, Marilena Poxleitner, Bredi Tako, Dominik Sonanini, Balaji Krishnamachary, Sanhita Sinharay, Birgit Fehrenbacher, Irene Gonzalez-Menendez, Felix Reckmann, David Bomze, Lukas Flatz, Daniela Kramer, Martin Schaller, Stephan Forchhammer, Zaver M. Bhujwalla, Leticia Quintanilla-Martinez, Klaus Schulze-Osthoff, Mark D. Pagel, Marieke F. Fransen, Martin Röcken, André F. Martins, Bernd J. Pichler, Kamran Ghoreschi, Manfred Kneilling
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L
Externí odkaz:
https://doaj.org/article/b3fa661fa2c8409a83b991ccda94efe7
Autor:
Jule Focken, Jasmin Scheurer, Annika Jäger, Christian M. Schürch, Sofie Kämereit, Simon Riel, Martin Schaller, Bettina Weigelin, Birgit Schittek
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113148- (2023)
Summary: Staphylococcus aureus is the most common cause of bacterial skin infections in humans, including patients with atopic dermatitis (AD). Polymorphonuclear neutrophils (PMNs) are the first cells to infiltrate an infection site, where they usual
Externí odkaz:
https://doaj.org/article/18ee08d62d964e14bd212678ec2667c9
Autor:
Lucas Mix, Manuel Knoll, Max-Felix Häring, Wolfgang Andreas Bethge, Jan C. Schröder, Stephan Forchhammer, Patrick Krumm, Christian M. Schürch, Martin Schaller, Claudia Lengerke
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Thymic carcinomas are exceedingly rare and very aggressive malignancies of the anterior mediastinum. While thymomas exhibit a high association with paraneoplastic syndromes, these phenomena are a rarity in thymic carcinomas. In general, acanthotic sy
Externí odkaz:
https://doaj.org/article/379809a67b5c4a34ab01df8955ac9c81
Autor:
Katharina Welsch, Martin Schaller
Publikováno v:
Journal of Dermatological Treatment, Vol 32, Iss 8, Pp 941-944 (2021)
Morbihan disease is characterized by erythema and solid edema in the two upper thirds of the face. Underlying factors are an imbalance in lymphatic drainage, chronic inflammation, and mast cells leading to fibrosis. Treatment options known thus far h
Externí odkaz:
https://doaj.org/article/bd1229810f2c49d681a552e4b9dda882
Autor:
Diana J. Vaca, Arno Thibau, Matthias S. Leisegang, Johan Malmström, Dirk Linke, Johannes A. Eble, Wibke Ballhorn, Martin Schaller, Lotta Happonen, Volkhard A. J. Kempf
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Bacterial adhesion to the host is the most decisive step in infections. Trimeric autotransporter adhesins (TAA) are important pathogenicity factors of Gram-negative bacteria. The prototypic TAA Bartonella adhesin A (BadA) from human-pathogen
Externí odkaz:
https://doaj.org/article/1fbcc65acb81458abd9396b4f2acebd2
Autor:
Ellen Brenner, Barbara F. Schörg, Fatima Ahmetlić, Thomas Wieder, Franz Joachim Hilke, Nadine Simon, Christopher Schroeder, German Demidov, Tanja Riedel, Birgit Fehrenbacher, Martin Schaller, Andrea Forschner, Thomas Eigentler, Heike Niessner, Tobias Sinnberg, Katharina S. Böhm, Nadine Hömberg, Heidi Braumüller, Daniel Dauch, Stefan Zwirner, Lars Zender, Dominik Sonanini, Albert Geishauser, Jürgen Bauer, Martin Eichner, Katja J. Jarick, Andreas Beilhack, Saskia Biskup, Dennis Döcker, Dirk Schadendorf, Leticia Quintanilla-Martinez, Bernd J. Pichler, Manfred Kneilling, Ralph Mocikat, Martin Röcken
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
The growth of cancer cells can be stably arrested by cytokine-induced senescence. Here, the authors show that cancers with defects in senescence-inducing cell cycle regulator pathways are resistant to immune checkpoint blockade.
Externí odkaz:
https://doaj.org/article/ffeefb0c18174583b0c353a1c64a24f9