Zobrazeno 1 - 10
of 800
pro vyhledávání: '"Martin, Reincke"'
Autor:
Zheng Fan, Mara Karakone, Shunmugam Nagarajan, Nadine Nagy, Wiebke Mildenberger, Ekaterina Petrova, Laura Catharina Hinte, Mitchell Bijnen, Philipp Häne, Eric Nelius, Jing Chen, Irina Ferapontova, Ferdinand von Meyenn, Francesco Trepiccione, Mesut Berber, David Penton Ribas, Anne Eichmann, Maria-Christina Zennaro, Norihiko Takeda, Jens W. Fischer, Ariadni Spyroglou, Martin Reincke, Felix Beuschlein, Johannes Loffing, Melanie Greter, Christian Stockmann
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114395- (2024)
Summary: Macrophages play crucial roles in organ-specific functions and homeostasis. In the adrenal gland, macrophages closely associate with sinusoidal capillaries in the aldosterone-producing zona glomerulosa. We demonstrate that macrophages preser
Externí odkaz:
https://doaj.org/article/02b69b219d364673aaf81f6bfedf2bb0
Autor:
Sonja Kunz, Xiao Wang, Uta Ferrari, Michael Drey, Marily Theodoropoulou, Katharina Schilbach, Martin Reincke, Margit Heier, Annette Peters, Wolfgang Koenig, Tanja Zeller, Barbara Thorand, Martin Bidlingmaier
Publikováno v:
Endocrine Connections, Vol 13, Iss 1, Pp 1-13 (2023)
Objective: Measurements utilizing commercially available sets of reagents for determination of steroid hormone profiles by liquid chromatography–tandem mass spectrometry (LC-MS/MS) have become increasingly important for routine laboratories. Howeve
Externí odkaz:
https://doaj.org/article/e5c662beeeee4acda3054b385de41eed
Autor:
Jessica Frey, Leah T. Braun, Laura Handgriff, Benjamin Kendziora, Martin R. Fischer, Martin Reincke, Laura Zwaan, Ralf Schmidmaier
Publikováno v:
BMC Medical Education, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Diagnostic errors in internal medicine are common. While cognitive errors have previously been identified to be the most common contributor to errors, very little is known about errors in specific fields of internal medicine such
Externí odkaz:
https://doaj.org/article/cb482d59b9784d2eafccd8f2ee097a72
Autor:
Leah T. Braun, Andrea Osswald, Stephanie Zopp, German Rubinstein, Frederick Vogel, Anna Riester, Jürgen Honegger, Graeme Eisenhofer, Georgiana Constantinescu, Timo Deutschbein, Marcus Quinkler, Ulf Elbelt, Heike Künzel, Hanna F. Nowotny, Nicole Reisch, Michaela F. Hartmann, Felix Beuschlein, Jörn Pons-Kühnemann, Martin Reincke, Stefan A. Wudy
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104907- (2024)
Summary: Background: Diagnosing Cushing’s syndrome (CS) is highly complex. As the diagnostic potential of urinary steroid metabolome analysis by gas chromatography-mass spectrometry (GC-MS) in combination with systems biology has not yet been fully
Externí odkaz:
https://doaj.org/article/150c72c68c42466f90f11b1e75850b6a
Autor:
Sharmilee Vetrivel, Mariangela Tamburello, Andrea Oßwald, Ru Zhang, Ali Khan, Sara Jung, Jessica E. Baker, William E. Rainey, Elisabeth Nowak, Barbara Altieri, Mario Detomas, Deepika Watts, Tracy Ann Williams, Ben Wielockx, Felix Beuschlein, Martin Reincke, Silviu Sbiera, Anna Riester
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundWe performed a transcriptomic analysis of adrenal signaling pathways in various forms of endogenous Cushing’s syndrome (CS) to define areas of dysregulated and druggable targets.MethodologyNext-generation sequencing was performed on adren
Externí odkaz:
https://doaj.org/article/06a80babc7d747e8a08bb4d32b7074de
Autor:
Hanna F. Nowotny, Thomas Marchant Seiter, Jing Ju, Adrian Gottschlich, Holger Schneider, Stephanie Zopp, Frederick Vogel, Lea Tschaidse, Matthias K. Auer, Christian Lottspeich, Sebastian Kobold, Simon Rothenfusser, Felix Beuschlein, Martin Reincke, Leah Braun, Nicole Reisch
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPatients with primary adrenal insufficiency (PAI) suffer from increased risk of infection, adrenal crises and have a higher mortality rate. Such dismal outcomes have been inferred to immune cell dysregulation because of unphysiological co
Externí odkaz:
https://doaj.org/article/31411e1bff0346db9eb92c284fd78142
Autor:
Wei Zhang, Hanna Nowotny, Marily Theodoropoulou, Julia Simon, Charlotte M. Hemmer, Martin Bidlingmaier, Matthias K. Auer, Martin Reincke, Henriette Uhlenhaut, Nicole Reisch
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
PurposeE47 has been identified as a modulating transcription factor of glucocorticoid receptor target genes, its loss protecting mice from metabolic adverse effects of glucocorticoids. We aimed to analyze the role of E47 in patients with endogenous g
Externí odkaz:
https://doaj.org/article/d1bf79e6bbda49499398c3a1de9924ab
Autor:
Claudia Irene Maushart, Wenfei Sun, Alaa Othman, Adhideb Ghosh, Jaël Rut Senn, Jonas Gabriel William Fischer, Philipp Madoerin, Rahel Catherina Loeliger, Robyn Melanie Benz, Martin Takes, Christoph Johannes Zech, Alin Chirindel, Felix Beuschlein, Martin Reincke, Damian Wild, Oliver Bieri, Nicola Zamboni, Christian Wolfrum, Matthias Johannes Betz
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104771- (2023)
Summary: Background: Glucocorticoids (GCs) are widely applied anti-inflammatory drugs that are associated with adverse metabolic effects including insulin resistance and weight gain. Previous research indicates that GCs may negatively impact brown ad
Externí odkaz:
https://doaj.org/article/a6d01e6088a14d76a5d17b2b4c537a7a
Autor:
Nabeel Mansour, Andreas Mittermeier, Roman Walter, Balthasar Schachtner, Jan Rudolph, Bernd Erber, Vanessa F. Schmidt, Daniel Heinrich, Denise Bruedgam, Lea Tschaidse, Hanna Nowotny, Martin Bidlingmaier, Sonja L. Kunz, Christian Adolf, Jens Ricke, Martin Reincke, Nicole Reisch, Moritz Wildgruber, Michael Ingrisch
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectivesThe aim of this study was to investigate an integrated diagnostics approach for prediction of the source of aldosterone overproduction in primary hyperaldosteronism (PA).Methods269 patients from the prospective German Conn Registry with PA
Externí odkaz:
https://doaj.org/article/6f56cb01492147f6b9f6b34905fcae46
Autor:
Luis Gustavo Perez-Rivas, Julia Simon, Adriana Albani, Sicheng Tang, Sigrun Roeber, Guillaume Assié, Timo Deutschbein, Martin Fassnacht, Monica R. Gadelha, Ad R. Hermus, Günter K. Stalla, Maria A. Tichomirowa, Roman Rotermund, Jörg Flitsch, Michael Buchfelder, Isabella Nasi-Kordhishti, Jürgen Honegger, Jun Thorsteinsdottir, Wolfgang Saeger, Jochen Herms, Martin Reincke, Marily Theodoropoulou
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-10 (2022)
Abstract Corticotroph macroadenomas are rare but difficult to manage intracranial neoplasms. Mutations in the two Cushing’s disease mutational hotspots USP8 and USP48 are less frequent in corticotroph macroadenomas and invasive tumors. There is evi
Externí odkaz:
https://doaj.org/article/69ae7cb40ac1485db967aa56b5648d80