Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Martin, Pilhofer"'
Autor:
Jordan Costafrolaz, Gaël Panis, Bastien Casu, Silvia Ardissone, Laurence Degeorges, Martin Pilhofer, Patrick H Viollier
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002040 (2023)
The acquisition of multidrug resistance (MDR) determinants jeopardizes treatment of bacterial infections with antibiotics. The tripartite efflux pump AcrAB-NodT confers adaptive MDR in the polarized α-proteobacterium Caulobacter crescentus via trans
Externí odkaz:
https://doaj.org/article/6b81f6251fbe409f9bb1427f0d28b037
Autor:
Ann-Katrin Kieninger, Piotr Tokarz, Ana Janović, Martin Pilhofer, Gregor L. Weiss, Iris Maldener
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The filamentous cyanobacterium Nostoc regulates communication between sister cells via a conformational change in septal junctions. Here, the authors identify and characterize protein SepN as a component of septal junctions, and highlight the importa
Externí odkaz:
https://doaj.org/article/f7d0a8202a934f9bb46192b16cffe789
Autor:
Dario Hüsler, Pia Stauffer, Bernhard Keller, Desirée Böck, Thomas Steiner, Anne Ostrzinski, Simone Vormittag, Bianca Striednig, A Leoni Swart, François Letourneur, Sandra Maaß, Dörte Becher, Wolfgang Eisenreich, Martin Pilhofer, Hubert Hilbi
Publikováno v:
eLife, Vol 12 (2023)
The amoeba-resistant bacterium Legionella pneumophila causes Legionnaires’ disease and employs a type IV secretion system (T4SS) to replicate in the unique, ER-associated Legionella-containing vacuole (LCV). The large fusion GTPase Sey1/atlastin is
Externí odkaz:
https://doaj.org/article/657f53154fbe40e1be705fd5ac2662de
Autor:
Damián Lobato-Márquez, Jingwei Xu, Gizem Özbaykal Güler, Adaobi Ojiakor, Martin Pilhofer, Serge Mostowy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Septins are cytoskeletal proteins that assemble into complexes and contribute to immunity by entrapping intracellular bacteria in cage-like structures. Here, Lobato-Márquez et al. reconstitute septin cages in vitro using purified recombinant complex
Externí odkaz:
https://doaj.org/article/7bfe02646c054d8c8ec6e9ed6237ffa9
Autor:
Désirée Böck, Dario Hüsler, Bernhard Steiner, João M. Medeiros, Amanda Welin, Katarzyna A. Radomska, Wolf-Dietrich Hardt, Martin Pilhofer, Hubert Hilbi
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Legionnaires’ disease is a life-threatening pneumonia, which is characterized by high fever, coughing, shortness of breath, muscle pains, and headaches. The disease is caused by the amoeba-resistant bacterium L. pneumophila
Externí odkaz:
https://doaj.org/article/58c72492c5834d36850e5b5fde327730
Autor:
Piotr Szwedziak, Martin Pilhofer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Bacteria use contractile injection systems, such as type VI secretion systems (T6SS), to secrete proteins that mediate cell-cell interactions. Here, Szwedziak & Pilhofer show that both ends of a T6SS can attach to opposite sides of the cell, enabling
Externí odkaz:
https://doaj.org/article/56641665227f4686ae7539b3801989fa
Autor:
Jessica J Stanisich, Dawid S Zyla, Pavel Afanasyev, Jingwei Xu, Anne Kipp, Eric Olinger, Olivier Devuyst, Martin Pilhofer, Daniel Boehringer, Rudi Glockshuber
Publikováno v:
eLife, Vol 9 (2020)
The glycoprotein uromodulin (UMOD) is the most abundant protein in human urine and forms filamentous homopolymers that encapsulate and aggregate uropathogens, promoting pathogen clearance by urine excretion. Despite its critical role in the innate im
Externí odkaz:
https://doaj.org/article/6e2010ca76a24c7c9142814a5644bbca
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The cell biology of Chloroflexota is poorly studied. We applied cryo-focused ion beam milling and cryo-electron tomography to study the ultrastructural organization of thermophilic Roseiflexus castenholzii and Chloroflexus aggregans, and mesophilic
Externí odkaz:
https://doaj.org/article/ccd06926696245b69827d9234eae3029
Autor:
Stefan A Fattinger, Desirée Böck, Maria Letizia Di Martino, Sabrina Deuring, Pilar Samperio Ventayol, Viktor Ek, Markus Furter, Saskia Kreibich, Francesco Bosia, Anna A Müller-Hauser, Bidong D Nguyen, Manfred Rohde, Martin Pilhofer, Wolf-Dietrich Hardt, Mikael E Sellin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008503 (2020)
Salmonella enterica serovar Typhimurium (S.Tm) infections of cultured cell lines have given rise to the ruffle model for epithelial cell invasion. According to this model, the Type-Three-Secretion-System-1 (TTSS-1) effectors SopB, SopE and SopE2 driv
Externí odkaz:
https://doaj.org/article/5a9d7e06a10540bb8d6ba0e1370f2e5b
Autor:
Tobias Zachs, Andreas Schertel, João Medeiros, Gregor L Weiss, Jannik Hugener, Joao Matos, Martin Pilhofer
Publikováno v:
eLife, Vol 9 (2020)
Cryo-electron tomography (cryoET) has become a powerful technique at the interface of structural biology and cell biology, due to its unique ability for imaging cells in their native state and determining structures of macromolecular complexes in the
Externí odkaz:
https://doaj.org/article/1c120550bbd54b19979c2a1593731aa2