Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Martin, Pass"'
Autor:
Kristoffer Valerie, Stephen T. Durant, Martin Pass, Kan Chen, Yingchun Wang, Tianwei Zhang, Li Zheng, Ian P. Barrett, Aaron Smith, Joanne Wilson, Nicola Colclough, Jason Kettle, Sebastien L. Degorce, Bernard Barlaam, Nitai Mukhopadhyay, Jason M. Beckta, Jenna Kahn, Laura Biddlestone-Thorpe, Nicholas C.K. Valerie, Amrita Sule, Thomas A. Hunt, Kurt G. Pike, Alan Lau, Jennifer Vincent, Bhavika Patel, Andrew G. Thomason, Antonio Garcia-Trinidad, Lucy C. Riches, Elaine B. Cadogan, Paul Farrington, Rajesh Odedra, Victoria Sheridan, Gareth Hughes, Syed F. Ahmad, Jasmine Allen, Jeremy Karlin
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393ee016739d4d6ff0e2ec657589845d
https://doi.org/10.1158/1535-7163.22504764.v1
https://doi.org/10.1158/1535-7163.22504764.v1
Autor:
Kristoffer Valerie, Stephen T. Durant, Martin Pass, Kan Chen, Yingchun Wang, Tianwei Zhang, Li Zheng, Ian P. Barrett, Aaron Smith, Joanne Wilson, Nicola Colclough, Jason Kettle, Sebastien L. Degorce, Bernard Barlaam, Nitai Mukhopadhyay, Jason M. Beckta, Jenna Kahn, Laura Biddlestone-Thorpe, Nicholas C.K. Valerie, Amrita Sule, Thomas A. Hunt, Kurt G. Pike, Alan Lau, Jennifer Vincent, Bhavika Patel, Andrew G. Thomason, Antonio Garcia-Trinidad, Lucy C. Riches, Elaine B. Cadogan, Paul Farrington, Rajesh Odedra, Victoria Sheridan, Gareth Hughes, Syed F. Ahmad, Jasmine Allen, Jeremy Karlin
U87/Centrin2-EGFP/H2B-mCherry/puro cells were seeded on dishes with cover slip bottoms, treated with AZ32 (3 uM), and irradiated (5 Gy). Time-lapse videos were recorded intermittently (every 7 min) over 16 hrs. Treatment results in 11% aberrant mitos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d9bad2471d6722b3a914316ea1d053
https://doi.org/10.1158/1535-7163.22504755
https://doi.org/10.1158/1535-7163.22504755
Autor:
Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
PDF file - 73K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9ea91e81a67f3f040a1bb9626f1a13
https://doi.org/10.1158/1535-7163.22498635
https://doi.org/10.1158/1535-7163.22498635
Autor:
Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
PDF file - 84K, Correlation of AZD5363 activity in cell lines from different tumor types with RAS, PIK3CA and PTEN status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26adbc826f9cc85329a52ca84cf29cd2
https://doi.org/10.1158/1535-7163.22498644.v1
https://doi.org/10.1158/1535-7163.22498644.v1
Autor:
Sabina C. Cosulich, Stephen Green, Oona Delpuech, Robert McEwen, Urszula M. Polanska, Christine M. Chresta, Martin Pass, Kurt G. Pike, Teresa Klinowska, Graham Bigley, Barry R. Davies, Zoe Howard, Michael Grondine, James W.T. Yates, Celina M. D'Cruz, Teeru Bihani, Jon Curwen, Sylvie M. Guichard
Pharmacokinetics modelling of AZD2014 intermittent dosing schedule.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aab7bc29f3860fec33ee0af943823b0
https://doi.org/10.1158/1535-7163.22505970.v1
https://doi.org/10.1158/1535-7163.22505970.v1
Autor:
Kristoffer Valerie, Stephen T. Durant, Martin Pass, Kan Chen, Yingchun Wang, Tianwei Zhang, Li Zheng, Ian P. Barrett, Aaron Smith, Joanne Wilson, Nicola Colclough, Jason Kettle, Sebastien L. Degorce, Bernard Barlaam, Nitai Mukhopadhyay, Jason M. Beckta, Jenna Kahn, Laura Biddlestone-Thorpe, Nicholas C.K. Valerie, Amrita Sule, Thomas A. Hunt, Kurt G. Pike, Alan Lau, Jennifer Vincent, Bhavika Patel, Andrew G. Thomason, Antonio Garcia-Trinidad, Lucy C. Riches, Elaine B. Cadogan, Paul Farrington, Rajesh Odedra, Victoria Sheridan, Gareth Hughes, Syed F. Ahmad, Jasmine Allen, Jeremy Karlin
U87/shp53/Centrin2-EGFP/H2B-mCherry/shp53 cells were seeded on dishes with cover slip bottoms and irradiated (5 Gy). Time-lapse videos were recorded intermittently (every 7 min) over 16 hrs. Treatment results in 12% aberrant mitoses (see Fig. 3F).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e59ae0a5bd1c69ae1a3cc400be18041
https://doi.org/10.1158/1535-7163.22504752
https://doi.org/10.1158/1535-7163.22504752
Autor:
Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
PDF file - 81K, Correlation of AZD5363 activity in cell lines from different tumor types with PIK3CA and PTEN mutation status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58aca16ca8976daf5767839bc44394ac
https://doi.org/10.1158/1535-7163.22498647
https://doi.org/10.1158/1535-7163.22498647
Autor:
Sabina C. Cosulich, Stephen Green, Oona Delpuech, Robert McEwen, Urszula M. Polanska, Christine M. Chresta, Martin Pass, Kurt G. Pike, Teresa Klinowska, Graham Bigley, Barry R. Davies, Zoe Howard, Michael Grondine, James W.T. Yates, Celina M. D'Cruz, Teeru Bihani, Jon Curwen, Sylvie M. Guichard
HCC1428-eveR and HCC1428-LTED-eveR cell lines resistant to everolimus remain sensitive to dual mTORC1/2 inhibitor AZD2014.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbbecc1501da9a57ed9b2de4b62242f
https://doi.org/10.1158/1535-7163.22505973
https://doi.org/10.1158/1535-7163.22505973
Autor:
Kristoffer Valerie, Stephen T. Durant, Martin Pass, Kan Chen, Yingchun Wang, Tianwei Zhang, Li Zheng, Ian P. Barrett, Aaron Smith, Joanne Wilson, Nicola Colclough, Jason Kettle, Sebastien L. Degorce, Bernard Barlaam, Nitai Mukhopadhyay, Jason M. Beckta, Jenna Kahn, Laura Biddlestone-Thorpe, Nicholas C.K. Valerie, Amrita Sule, Thomas A. Hunt, Kurt G. Pike, Alan Lau, Jennifer Vincent, Bhavika Patel, Andrew G. Thomason, Antonio Garcia-Trinidad, Lucy C. Riches, Elaine B. Cadogan, Paul Farrington, Rajesh Odedra, Victoria Sheridan, Gareth Hughes, Syed F. Ahmad, Jasmine Allen, Jeremy Karlin
U87/Centrin2-EGFP/H2B-mCherry/puro cells were seeded on dishes with cover slip bottoms and irradiated (5 Gy). Time-lapse videos were recorded intermittently (every 7 min) over 16 hrs. Treatment results in 2.7% aberrant mitoses (see Fig. 3F).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8597de5b360dbd2701d63db0a2d2f9a5
https://doi.org/10.1158/1535-7163.22504758
https://doi.org/10.1158/1535-7163.22504758
Autor:
Martin Pass, Donald Ogilvie, Richard Luke, Rebecca Watson, Clare Lane, James Yates, Ken Page, Christine C. Chresta, Sabina Cosulich, Darren Cross, Sally-Ann Ricketts, Juliana Maynard, Qunsheng Ji, Beirong Gao, Jing Li, Jingchuan Zhang, De-Hua Yu, Claire Crafter, Phillippa Dudley, Hannah Greenwood, Barry R. Davies
PDF file - 88K, Quantification of cleaved caspase 3 activity in HCC-1187 xenografts following chronic dosing with 5 mg/kg once weekly docetaxel (taxotere), 150 mg/kg bid AZD5363, or a combination of these two agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3112b5ae732cb14b1fb9210be4bf92
https://doi.org/10.1158/1535-7163.22498638.v1
https://doi.org/10.1158/1535-7163.22498638.v1