Zobrazeno 1 - 10
of 363
pro vyhledávání: '"Martin, Michaelis"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
There is clinical evidence showing that the Pelargonium sidoides root extract EPs 7630 is a safe and effective treatment for a range of acute infectious respiratory illnesses. Moreover, EPs 7630 has been shown to reduce the use of antibiotics, which
Externí odkaz:
https://doaj.org/article/9065d3d3aa3343b0b9ee0715b66145c8
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
This poster demonstrates the development of drug-resistant cancer cell lines and their application in cancer research.
Externí odkaz:
https://doaj.org/article/44aac78983104a70bd43d0168f83b387
Publikováno v:
Pharmacological Research, Vol 199, Iss , Pp 107043- (2024)
In the life sciences, there is an ongoing discussion about a perceived ‘reproducibility crisis’. However, it remains unclear to which extent the perceived lack of reproducibility is the consequence of issues that can be tackled and to which exten
Externí odkaz:
https://doaj.org/article/87123ce9a9084f04a3b97445fb102a47
Autor:
Lisa Rösch, Sonja Herter, Sara Najafi, Johannes Ridinger, Heike Peterziel, Jindrich Cinatl, David T. W. Jones, Martin Michaelis, Olaf Witt, Ina Oehme
Publikováno v:
Molecular Oncology, Vol 17, Iss 1, Pp 37-58 (2023)
Chemotherapy resistance is a persistent clinical problem in relapsed high‐risk neuroblastomas. We tested a panel of 15 drugs for sensitization of neuroblastoma cells to the conventional chemotherapeutic vincristine, identifying tariquidar, an inhib
Externí odkaz:
https://doaj.org/article/0cc0e9cead214d9db95d54cee9506c3a
Autor:
Ria Winkelmann, Katrin Bankov, Claudia Döring, Jaroslav Cinatl, Sebastian Grothe, Florian Rothweiler, Martin Michaelis, Christina Schmitt, Peter J. Wild, Melanie Demes, Jindrich Cinatl, Stefan Vallo
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background/Introduction Penile cancer is a rare disease in demand for new therapeutic options. Frequently used combination chemotherapy with 5 fluorouracil (5-FU) and cisplatin (CDDP) in patients with metastatic penile cancer mostly results
Externí odkaz:
https://doaj.org/article/0c47687f028c4863a68fab0fed852dba
Autor:
Ankur Chakravarthy, Ian Reddin, Stephen Henderson, Cindy Dong, Nerissa Kirkwood, Maxmilan Jeyakumar, Daniela Rothschild Rodriguez, Natalia Gonzalez Martinez, Jacqueline McDermott, Xiaoping Su, Nagayasau Egawa, Christina S. Fjeldbo, Vilde Eide Skingen, Heidi Lyng, Mari Kyllesø Halle, Camilla Krakstad, Afschin Soleiman, Susanne Sprung, Matt Lechner, Peter J. I. Ellis, Mark Wass, Martin Michaelis, Heidi Fiegl, Helga Salvesen, Gareth J. Thomas, John Doorbar, Kerry Chester, Andrew Feber, Tim R. Fenton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Human papillomavirus (HPV) is a known cause of cervical cancer. Here, the authors perform a multi-omic analysis using published cervical squamous cell carcinoma cohorts from the USA, Europe, and SubSaharan Africa and identify two cervical squamous ce
Externí odkaz:
https://doaj.org/article/9a5c4607e718467ca9be497358a18ce0
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Objective: Osteoarthritis (OA) is a common joint disorder often affecting the knee. It is characterized by alterations of various joint tissues including subchondral bone and by chronic pain. Anti-nerve growth factor (NGF) antibodies have demonstrate
Externí odkaz:
https://doaj.org/article/d79314ab609c4c5884a7e98ba329889d
Autor:
Denisa Bojkova, Tamara Rothenburger, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindrich Cinatl
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/32d4ffb094894528b54b4ba4459985d6
Autor:
Linus Gohlke, Ahmad Alahdab, Angela Oberhofer, Karolina Worf, Stefan Holdenrieder, Martin Michaelis, Jindrich Cinatl, Christoph A Ritter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14742 (2023)
Despite recent advances in the treatment of non-small cell lung cancer (NSCLC), acquired drug resistance to targeted therapy remains a major obstacle. Epithelial-mesenchymal transition (EMT) has been identified as a key resistance mechanism in NSCLC.
Externí odkaz:
https://doaj.org/article/b0c2a954a9e847879adc7951339b5fce
Autor:
Denisa Bojkova, Philipp Reus, Leona Panosch, Marco Bechtel, Tamara Rothenburger, Joshua D. Kandler, Annika Pfeiffer, Julian U.G. Wagner, Mariana Shumliakivska, Stefanie Dimmeler, Ruth Olmer, Ulrich Martin, Florian W.R. Vondran, Tuna Toptan, Florian Rothweiler, Richard Zehner, Holger F. Rabenau, Karen L. Osman, Steven T. Pullan, Miles W. Carroll, Richard Stack, Sandra Ciesek, Mark N. Wass, Martin Michaelis, Jindrich Cinatl, Jr.
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105944- (2023)
Summary: Reliable, easy-to-handle phenotypic screening platforms are needed for the identification of anti-SARS-CoV-2 compounds. Here, we present caspase 3/7 activity as a readout for monitoring the replication of SARS-CoV-2 isolates from different v
Externí odkaz:
https://doaj.org/article/4a88cf04c85349bf88133734b02945c5